#cw: medical abuse | Explore Tumblr Posts and Blogs

msfcatlover · 1 year

Text

Changeling!Tim’s childhood is... actually kinda horrifying, when anyone looks into it.

(CW for forced medical procedures, and abuse in the form of temporary imprisonment. Also, minor self-harm, and… I don’t know what you call “eating something that will make you sick so your parents don’t get mad at you,” but I know it ain’t good.)

Tim had pretty pronounced fangs when he was younger, which his parents were just planning to wait out... until he was fast coming up on 10 and it was clear Tim wasn’t going to lose his teeth. A quick x-ray proved that Tim didn’t have adult teeth to grow in, just the one set he came with, and the fangs were only getting more obvious. His parents found an orthodontist willing to yank the fangs & wire up the rest of Tim’s teeth with braces to force them to look smooth & even as he grew up. (The doctor kept the teeth as a curiosity, and a decade later Damian will track that doctor down to steal them back.)

Something even Tim didn’t realize until he had to undergo a full Justice League-grade medical exam in preparation for becoming Robin, is that the tiny points on his ears aren’t natural. They have no idea what the ears of the baby Jack & Janet received looked like, but Tim’s points are actually mostly scar tissue. (Bruce puts it down as “a cosmetic procedure not dissimilar to ear cropping in canines” and tries not to feel sick.)

(There was also a period where the Drakes did an awful lot of research into cosmetic eye surgeries, but they eventually gave up. Apparently, it was a bigger concern that their son might end up blinded than that his eyes glowed in the dark and/or were the wrong color.)

As I mentioned before, Tim’s parents trim his thorns so that nobody goes to ruffle Tim’s hair and realizes he’s not human. He... actually started doing it himself when he decided to become Robin, because Tim has seen Bruce ruffle Jason & Dick’s hair so many times and didn’t want to hurt Bruce (or experience the absolute agony of having a thorn get caught in Bruce’s gloves and end up ripped out of Tim’s scalp,) as well as not wanting to give away Tim’s own inhuman nature with the single most obvious trait he has. (When the rest of the family find out, they are horrified and insist that Tim stop doing that. Instead of hair-ruffles, Tim gets hair-strokes that go only in one direction, bumping harmlessly over the curved outer edges of his thorns; it’s actually very soothing for both parties. Everyone absolutely uses Tim’s thorns as a stim toy, as long as Tim’s okay with it.)

Tim’s parents also hire an in-house barber to cut Tim’s hair, so they can make sure it’s “properly disposed of.” (Tim’s nightmares always smell faintly of burning hair.)

Tim wears fancy dress gloves to all dinners, because with the uppercrust you never know if someone’s going to bring out the real silverware. (If someone tells him to take off the gloves or Tim’s skin happens to brush up against somebody’s jewelry, Tim just sorta has to... deal. It’s rude to rush out or refuse your hosts, after all.) (Fortunately, Dick and the Titans all prefer reusable plastic silverware. And as soon as any Bat finds out about Tim’s fae nature, Wayne Manor quickly switches to stainless steel.)

It’s nearly impossible to know if a meal was prepared with iodized salt or non-iodized salt until it’s already in Tim’s mouth and the burning-itching discomfort of coming in contact with an anti-fae substance begins. It’s rude not to at least try the food someone offers you, and it’s even ruder to just spit something out, especially out in public. At least Tim doesn’t usually have to fake it when he says he’s not feeling well in order to stop eating. (Tim doesn’t tell the Waynes about this until that medical exam, where he kinda jokes about being allergic to salt and someone’s like, “Wait, how do you eat? Everything has salt in it nowadays.” Alfred rather forlornly puts his sea salt up on the top shelf and buys a jar of iodized table salt on the next grocery run.)

Tim’s blood is immediately identifiable because it has chloroplasts in it. No, he’s not actually a plant; yes, he can perform limited photosynthesis. No, Tim was not aware of this about himself, he’s never been allowed to give blood before, and like??? Sure, he figured out he was a changeling, but that does not immediately translate to, “Oh, I should test my blood for plant cells!”

Tim’s room doesn’t look any different from any other boy his age... except for three nails over the door on the outside. For the iron horseshoe Tim’s parents hang there sometimes, when they don’t want him to bother them or when he’s grounded. (Thankfully, it's been very rare for Tim to actually be trapped in his room, as setting up a salt line on his windowsills has always been... well, he's not sure. A step too far, even for his parents? A step too many to remember and/or perform in the heat of the moment? Something they don’t even realize is necessary, assuming the horseshoe prevents Tim from leaving the room at all rather than simply crossing that one threshold? Tim doesn’t like to think about it. Tim typically stays in his room anyway when he feels the swooping nausea of it hanging over his door, if only so his parents don’t find him missing and decide sealing the windows is something they ought to be doing. Trapped not by any law or binding ritual, but by Tim’s own admittedly rare fear of consequences.) (After Tim is snatched by faerie hunters, Jason and Dick are the ones who search Tim’s house. There’s a moment of silence when they find the horseshoe and realize what the nails are for. “I really hope I don’t have to point this out,” Jason says, in the tone of someone who’s going to do it anyway, “but it’s never a good sign when a kid’s bedroom has a lock on the outside.”)

81 notes · View notes

immediatebreakfast · 10 months

Text

I cannot begin to think about the... Everything that happened in this entry. It's either the death of the sparrows, Seward's unethical ramblings about how the future of science is maybe in his hands, or what could possibly come next.

Or the extreme disregard for Renfield's well being, and health after he completed his experiment. An experiment that shouldn't have happened because this old man's caretaker is far too interested in how he conducts a façade of madness that ends up worsening the mental problems that he already had.

Even if Renfield ate all of the sparrows, and even if I'm sad for the little creatures, what he goes through after he eats them is bad enough.

"The attendant has just been to me to say that Renfield has been very sick and has disgorged a whole lot of feathers." - Jack Seward, july 20.

"Oh yeah doctor that old patient that you have obssesing about for the last few weeks? Yeah he puked a bunch of dead birds, and is now sick." Is Seward going to do something about that, or is he just going to send a cleaning worker to clean up the mess? I don't know, and neither the text answers that. However, I really don't like the possible subtextual comment of Seward not helping Renfield with his physical illness.

And then this:

"I gave Renfield a strong opiate to-night, enough to make even him sleep, and took away his pocket-book to look at it." - Jack Seward, july 20.

The disregard, and violation of Renfield's privacy for "science" was sick. This old man has been coughing up feathers, and dead bird remains for almost an entire day, and the only thing that apparently matters is what is written in a diary. To the point of druggging Renfield without even checking if he was at least less sick than before.

Is Renfield now a patient in only name Seward? Is his well being an after thought to your ramblings about science? How the cage holds the man, and even if he tries to get free from the walls with his mind, at the end of the day there is no escape.

#This entry is too much #How did I not notice how bad it was last year?????#dracula daily #dracula #renfield #r.m. renfield #jack seward #cw: medical abuse

41 notes · View notes

nny11writes · 1 month

Text

WiP Wednesday - The Research Hall

“I- I am sorry.” The patient on the bed speaks, their voice higher, more feminine than the last she passed. “I’m, you see, better now. I won’t do it again, I promise. I promise!”

Catra stood frozen over their bed, sword shaking in her hand as she stared down at their emaciated, mangled body.

“And I could send you there, you know.” Shadow Weaver was drunk but at least tonight she was a happy drunk, for what little that was worth. “You think you have a difficult life now? Ha! You’d be strapped down tight to your bed up there, stewing in your own filth as they take and take or give and give. And- and! Eventually you’d end up like the rest too.”

Catra clenched her jaw as she pulled uselessly at the thick leather straps keeping her on Weaver’s table out of nervousness. It wasn’t difficult for her to imagine the life of a patient. No. Not anymore.

Shadow Weaver pitched her voice into a pathetic, mewling imitation that Catra flushed with shame to hear. Her own cadence and voice thrown back in her face. “Oh Lady Weaver, OH Lady Weaver! Please, help me, Lady Weaver! Ha! HA! Wouldn’t that be a sight, hmm? I might even go back to watch you squirm, child.”

She dissolved into giggles as if it was the silliest, funniest joke she could conceive.

Catra’s fingers felt numb with cold at the thought.

She had assumed it was exaggerated in some way. Minister Weaver always told a version of the truth, but rarely was she honest. What else had she promised that Catra would find to ring true?

“I am so very sorry,” the patient gasped and writhed, kicking their feet just enough to squish through the remains of their own excrement. “I’m guilty, I know it, but I- I’m better now! You can see it for yourself, I’m much better now. I won’t do it again, I p-promise, L-lady Wea-”

Catra gasped for air, choking on the ammonia and rot and decay as she stared at the pulsing head below her. Her sword sunk to the hilt into the patient’s throat cut off their words, but their skin still pulsated. A soft sloshing sound back and forth, back and forth, back and forth.

#catra #melog #she ra #spop #bloodborne AU #cw: medical torture #cw: medical abuse #cw: child abuse

6 notes · View notes

sinclair-wax-fan · 2 years

Text

I don’t think Victor actually saw patients at the Sinclair’s home during his time as a doctor.

I think all the medical equipment we saw only came later, when Trudy was very sick, with Victor investing in some last ditch off the book medical experiments to try and save her.

And when I say “save her”--there’s actually three versions of how that could be interpreted:

1) Victor kept attempting medical solutions long past when other doctors would have just said “all we can do is make her comfortable,” partially out of co-dependency and largely out of professional pride--and probably greatly to the detriment of his wife’s quality of life in those last few months.

2) Trudy was not actually in immediate danger of dying due to the tumor, rather that it just altered her personality so drastically (delusions, outburst of violent rages, ongoing disorientation, even possible neurological affects that caused her to loose partial use of her hands or vision--thus requiring her be physically cared for) that he decided to “fix her”/”bring back” the woman he loved--in a manner involving deeply unethical and likely unnecessary medical treatments.

(This is the interpretation I tend to gravitate to personally--because I think it most reflects how Victor and Trudy saw the world, as extrapolated by their handling of Bo: utilizing any method available--no matter how extreme or unethical or abusive--they thought would make a person behave “the right way.”)

3) The darkest timeline: Trudy never had a tumor. She simply had a severe mental/personality disorder Victor grew tired of dealing with and he decided to try and “fix her.”

(I personally find this a little too extreme for my taste, but it would be in-line with HoW’s schlocky over the top melodrama.)

Regardless of how it went down:

I personally headcanon that at the end--whether due to affects of Victor’s medical experiments or him simply being unable to stop growth of the tumor--Trudy was largely gone mentally, nearly reduced to catatonia, but still very much alive. Possibly--though possibly not, depending on how you want to spin it--with months or even years ahead of her.

I think Victor killed himself partially out of shame and largely out of not wanting to deal with the reality of the situation.

He didn’t want to be left the single father of three high-needs teenagers, while forced to care for his now disabled wife, who he now viewed as nothing more than a testament of his professional and personal failures.

So he killed himself, and left his kids to deal with the fallout.

And this is all a very long way of sharing this final headcanon:

I don’t think Trudy simply passed away on her own.

I think Vincent euthanized her.

Now--as I said above, I personally like to believe Trudy really did have a tumor and I think it’s clear that Vincent genuinely loved his mother. So, I don’t think this would have been his go too option right out of the gate--I think he would have tried to carrying on care for her on his own for several months. Eventually, however, I think it would quickly wear him down to the point he could no longer continue doing so.

And at that point--after all the behavior that had been modeled for him, with the emphasis that you never revealed “family matters” to outside people and the glaring fact that Bo was likely actively beginning to kill people at this point--I think he would have seen euthanizing her as the only option available to him, and likely the kindest thing to do, in his mind.

I think he also never told Bo what he did.

(For many complicated reasons.)

At the end of the day, I think Trudy’s death is the one death Vincent has caused that he harbors real guilt over.

#vincent sinclair #trudy sinclair #victor sinclair #House of Wax #cw: abelism #cw: suicide #cw: medical abuse #cw: assisted suicide

16 notes · View notes

maximumsunshine · 2 years

Text

Man. Speaking of cancer trauma. I really was a cancer patient for 6 fucking years. And only 6 years because when they couldn't immediately find the tumor with like 1 CT and some scopes in year 1, they just stopped looking, no matter how much i begged, and just kept on giving me iron infusions and blood transfusions to treat the severe anemia the cancer attached to the outside of my small intestine (where scopes couldn't see it) caused, telling me for years I just didn't make my own blood. This doctor telling me this was a hemotologist (blood) oncologist (cancer) specialist. He just... refused to look for cancer.

Once someone actually LOOKED for cancer last year (so 6 years in) they found it and completely removed it within like 48 hours of me showing up to the ER (of a different system entirely) with a hemoglobin of 4.

I get that in year 1 the tumor was too small to be easily found by a CT scan, i guess. And i get it was on the outside wall amd thus all the cameras shoved through my system top to bottom bottom to top were never going to find it. But i just feel like. It was a lot of effort for a year. And then they just fucking gave up, told me my blood making machine was broken, and asked if I had tried weight loss about it.

Something Something fat female presenting patients not being taken seriously.

#cw: medical trauma #cw: medical abuse #cw: medical neglect #got a whole new crew of followers so y'all don't know the Max lore #so i guess i should tag and warn y'all there is medical abuse found within these walls

25 notes · View notes

leebird-simmer · 1 year

Text

All About: Schizophrenia

[Note: If you have schizophrenia/are schizophrenic (not sure if the community prefers person-first or identity-first language, so I’m giving y’all both), please feel free to chime in with corrections or additions in the comments. I don’t know what I don’t know, but I’m always willing to learn.]

Pathology = Study of Disease

Pathology addresses the following components of disease:

cause/etiology

mechanisms of development (pathogenesis)

structural alterations of cells, tissues, and organs

functional alterations of cells, tissues, and organs (pathophysiology)

the consequences of those changes (clinical symptoms)

Characteristics

The most typical feature of schizophrenia is psychosis:

severe distortions of reality and perception

disturbances in intellectual function, affect, motivation, social relationships, and motor behavior

relapsing episodes

- This can be so incapacitating that voluntary or involuntary hospitalization is required.

Classification of Mental Disorders in the DSM-5

Psychiatric disorders are listed in the DSM = Diagnostic and Statistical Manual of Mental Disorders.

- published by the American Psychiatric Association (APA)

- currently on 5th edition (2013)

1.2 Section II: diagnostic criteria and codes

- 1.2.1 Neurodevelopmental disorders

- 1.2.2 Schizophrenia spectrum and other psychotic disorders

- 1.2.3 Bipolar and related disorders

- 1.2.4 Depressive disorders

- 1.2.5 Anxiety disorders

- 1.2.6 Obsessive-compulsive and related disorders

- 1.2.7 Trauma- and stressor-related disorders

- 1.2.8 Dissociative disorders

- 1.2.9 Somatic symptom and related disorders

- 1.2.10 Feeding & eating disorders

- 1.2.11 Sleep-wake disorders

- 1.2.12 Sexual dysfunctions

- 1.2.13 Gender dysphoria

- 1.2.14 Disruptive, impulse-control, and conduct disorders

- 1.2.15 Substance-related and addictive disorders

- 1.2.16 Neurocognitive disorders

- 1.2.17 Paraphilic disorders

- 1.2.18 Personality disorders

Diagnosis

Criterion A: Characteristic Symptoms

- Two or more of the following, each present for a significant portion of time during a 1-month period (or less if successfully treated). At least one of these should include symptoms 1-3 (positive symptoms).

Delusions

Hallucinations

Disorganized speech

Disorganized or catatonic behavior

Negative symptoms (e.g. blunted emotions)

Cognitive deficits

Criterion B: Social/Occupational Dysfunction

Criterion C: Duration of Six Months or More

Criterion D: Schizoaffective and Mood Disorder Exclusion

Criterion E: Substance/General Mood Condition Exclusion

Criterion F: Relationship to Global Development Delay or Autism Spectrum Disorder

[Note: If you’ve been misdiagnosed with schizophrenia when you were actually dealing with schizoaffective disorder, autism, substance use, a mood disorder, etc., please feel free to share your experience in the comments.]

Delusion: a belief that is held with strong conviction, despite superior evidence to the contrary.

- Karl Jaspers (1913) established three main criteria for a belief to be considered delusional:

certainty (held with absolute conviction)

incorrigibility (not changeable by compelling counter-argument or proof to the contrary)

impossibility or falsity of content (implausible, bizarre, or patently untrue)

- Examples:

Delusion of persecution involving the individual’s belief that others are spying on or planning to harm them

Delusions that thoughts are imposed from an outside source, such as outer space

Hallucinations: pathological forms of perception.

- Auditory hallucinations are frequent and are usually voices that are insulting or commanding.

- Visual hallucinations are rarer (in catatonic schizophrenia). More typical with epilepsy or hallucinogen use.

- Gustatory, olfactory, and somatic sensations also occur [note: I don’t have stats on the frequency of these; please share them if you got ‘em.]

Disorganized Speech

- sometimes called “word salad”

- frequent change of conversation topics with no connection between sentences

- speech can follow grammatical rules, but content makes little sense

Disorganized or Catatonic Behavior

- Motor activity is reduced and characterized by inappropriate and bizarre postures, rigidity, or “purposeless” and stereotyped movements (e.g. rocking or pacing).

- At times, people with schizophrenia (particularly the paranoid type) can become agitated and/or violent.

Catatonia: motor immobility and behavioral abnormality manifested by stupor.

- Stupor = lack of critical cognitive function and a level of consciousness wherein the person is almost entirely unresponsive and only responds to base stimuli such as pain.

Negative Symptoms

Blunted emotions = emotions may be absent or totally inappropriate to the situation. Sudden and unpredictable changes of emotion are also common.

Inability to experience pleasure

Social withdrawal

Lack of eye contact

Lack of motivation

Poverty of speech

Cognitive Deficits

Schizophrenia is classified as a thought disorder, characterized by illogical thinking, lack of reasoning, and inability to recognize reality.

Cognitive symptoms include impaired working memory, executive functioning, and attention. Many cognitive deficits impair the ability to function at school, at work, etc.

Onset of Schizophrenia

- Symptoms most often begin during the late teenage years and early twenties, but there are gender differences. After age 36, more women than men experience their first episode.

Etiology of Schizophrenia

- Although schizophrenia was described as early as 1000 BC, its causes remain unknown.

- It is increasingly regarded as a neurodevelopmental disorder with a strong genetic component.

Importance of genetics is shown by many family, twin, and adoption studies.

Other factors must be involved as well; we’re still figuring those out.

Lifetime risks of developing schizophrenia among relatives of an affected individual

Events during perinatal brain development can contribute to the occurrence of schizophrenia.

- These complications include:

brain injury during pregnancy or delivery caused by oxygen deprivation

drug use

exposure to viral infection (ex. measles) in the 2nd trimester

endocrine disorders

severe malnutrition

- During adolescence, a period of significant brain development, excessive synaptic pruning can result in loss of cortical gray matter.

- Cannabis use during adolescence might increase the risk.

Neurobiology of Schizophrenia: Structural Changes

- Recent advances in technology have revealed abnormalities of brain structure and function in individuals with schizophrenia.

- Many studies show cerebral atrophy and enlargement of fluid-filled ventricles following cell loss.

Brain Imaging & Mental Disorders

- Brain imaging techniques are currently not used to diagnose mental disorders.

- Imaging is currently used for research purposes and is helping to identify the brain regions involved in different pathologies.

- Numerous studies show that hippocampal cells of patients with schizophrenia are more disorganized than those of healthy subjects.

Neurobiology of Schizophrenia: Functional Changes

- Brain functional changes include reduced function of the prefrontal cortex (PFC), called hypofrontality.

- Reduced blood flow is associated with less glucose use, which indicates how active the brain cells are.

- Imaging studies show less blood flow to the frontal cortex when people with schizophrenia are performing cognitive tasks, such as the Wisconsin Card Sorting Test (WCST).

Neurobiology of Auditory Hallucinations

- Reduced gray matter volume in the temporal lobe

- Impaired processing in a prefrontal and temporal lobe neuronal network, due to hyper-activation of temporal lobe regions, including the auditory cortex, which is not inhibited due to impairment of prefrontal executive inhibitory functions.

Neurobiology of Schizophrenia: Functional Changes

- Eye-movement dysfunctions such as inability to visually track an object.

- Failure to track is also common in relatives of schizophrenic patients. The defective eye-tracking gene may be inherited along with the genes for schizophrenia.

The dopamine hypothesis = excess DA function results in positive symptoms of schizophrenia.

- It was suggested by the fact that amphetamine (which increases dopamine) can produce a psychotic reaction in healthy individuals, which can be reversed by DA antagonists.

- There is a strong correlation between D2 receptor blockade and reduction of schizophrenic symptoms.

DA imbalance hypothesis:

reduced DA function in mesocortical neurons (negative symptoms and impaired thinking) = D1 receptors

excess DA function in mesolimbic neurons (positive symptoms) = D2 receptors

Hypoglutamate hypothesis:

- Blocking NMDA receptors with PCP or ketamine produces schizophrenia-like symptoms in healthy individuals and exacerbates symptoms in schizophrenic patients.

- PCP and ketamine produce both the positive and negative symptoms.

- Antipsychotic drug clozapine interacts with the glutamate receptor and increases glutamate levels in the PFC of rats.

Schizophrenia: Treatments

- Before drug therapy, patients were confined to mental hospitals where treatment was limited to isolation or restraint, “shock” therapy using insulin-induced seizures or electrical currents, and surgery such as prefrontal lobotomy.

Lobotomy: consists of cutting the connections to and from the prefrontal cortex.

- controversial procedure accompanied by frequent and serious side effects

- was used to treat psychiatric (and occasionally other) conditions from 1935 till mid-1950s [note: gay men and lesbians were subjected to lobotomies in an attempt to “cure” them during this time period.]

- The dramatic decrease in the number of resident patients in state and municipal mental hospitals in the United States began after 1955, when psychoactive drugs were introduced into widespread therapeutic use.

Anti-psychotic Drugs

Neuroleptics = older term for anti-psychotic drugs

- Typical anti-psychotics: have motor side effects (ex. Chlorpromazine, Haloperidol)

- Atypical anti-psychotics (2nd generation): fewer side effects (ex. Clozapine, Risperidone)

- Effectiveness of these drugs has been demonstrated hundreds of times, especially for positive symptoms.

- Negative and cognitive symptoms are more resistant to treatment.

- The law of thirds = 1/3 of patients respond well to treatment, 1/3 shows significant improvements but is vulnerable to relapse, and 1/3 fails to respond.

After initial recovery, anti-psychotic drugs are prescribed as maintenance therapy to prevent relapse.

- Unpleasant side effects cause many patients to stop treatment.

- Psychotherapy and group therapy are important additions to drug therapy.

Anti-psychotic drugs block D2 receptors.

- A strong correlation exists between ability of a drug to displace a radio-labeled ligand on DA receptors and average clinical daily dose required.

- D2 receptors are located in the basal ganglia, nucleus accumbens, amygdala, hippocampus, and less in the cerebral cortex.

PET images show replacement of radio-labels on striatal D2 receptors by different anti-psychotic drugs.

The drugs also bind to other receptors, but there is no clear relationship between clinical effectiveness and binding to serotonin, adrenergic, histamine, or D1 receptors.

Anti-psychotics: Side Effects

Side effects depend on which receptor the drug binds to.

- Dopamine pathways in the brain are important for understanding drug action:

Nigrostriatal pathway (Substantia nigra ---> Striatum): Motor side effects

Hypothalamus ---> Pituitary gland pathway (regulates pituitary hormone secretion): Hormonal side effects

Parkinsonism: motor side effects that resemble symptoms of Parkinson’s disease:

tremors

akinesia (slowing or loss of voluntary movement)

muscle rigidity

restlessness (inability to sit still)

loss of facial expressions

- Parkinson’s is caused by loss of cell bodies in the substantia nigra, which gives rise to the nigrostriatal pathway.

- Lack of DA function in the striatum causes the motor effects.

Tardive dyskinesia (TD) is characterized by stereotyped involuntary movements, particularly of the face and jaw, quick and uncontrolled movements of the arms and legs, and other motor effects.

- Incidence of TD increases with duration of treatment.

Woman with tardive dyskinesia (TD)

- Neuroendocrine effects:

decreased sex drive

no menstruation

increased prolactin release

inhibition of growth hormone release

- Metabolic effects (typically significant weight gain)

- Inability to regulate body temperature

Neuroleptic malignant syndrome (NMS) is serious and life-threatening.

- characterized by fever, rigidity, altered consciousness, and autonomic nervous system inability (including rapid heart rate and fluctuations in blood pressure)

- Rapid diagnosis and immediate action have significantly reduced mortality risk.

Other side effects of anti-psychotics:

Blocking cholinergic synapses produces dry mouth, blurred vision, difficulty in urination, GI problems

Anti-adrenergic action leads to dizziness or blacking out

Many drugs also cause sedation

Anti-psychotics: Dependence

Anti-psychotic drugs causes little or no tolerance, physical dependence, or abuse potential, and have high therapeutic index.

- Lack of abstinence syndrome may be due to long half-life:

Haloperidol (20 hours)

Olanzapine (30 hours)

Aripiprazole (75 hours)

Atypical Anti-psychotics

“Atypical” or “second-generation” drugs reduce positive symptoms of schizophrenia as well as classical drugs, but without significant motor side effects.

- Some new drugs do not produce TD or increase prolactin secretion.

- Three types:

Selective D2 receptor antagonists

Dopamine system stabilizers

Broad-spectrum anti-psychotics

Dopamine system stabilizers:

Partial DA agonists compete with DA for receptors and reduce DA effect (ex. aripiprazole, trade name: Abilify)

Has few side effects

Little evidence of cardio-toxicity, weight gain, or motor side effects

Adverse effects such as headache, agitation, insomnia, and nervousness are minor.

Broad-spectrum anti-psychotics block other receptor types in addition of D2 receptors (ex. Clozapine, risperidone)

- Clozapine has weak affinities for D1 and D2 and strong affinities for serotonergic, muscarinic, histaminergic, and D4 receptors.

- It is more effective for patients who do not respond to total anti-psychotics.

- Clozapine has fewer motor side effects. However, it does have many other side effects because of its action on multiple receptors, including:

weight gain

sedation

agranulocytosis (a rare blood disorder that severely reduces number of white blood cells)

cardiac toxicity

- Clinical trials in the UK found that clozapine was superior to the other anti-psychotics in the treatment of negative symptoms.

- Clozapine can improve cognitive symptoms.

appears to be the only true “atypical” anti-psychotic, because no other 1st or 2nd generation anti-psychotics have this positive effect

The Search for a New Drug: Possible Approaches

(1) Enhance Acetylcholine: Clozapine is the only drug currently in use that enhances cognition. It does this by increasing acetylcholine release in the hippocampus.

(2) Selectively enhance D1 receptor signaling in PFC with D1 agonists.

Hypofrontality is associated with reduced DA function in PFC, especially at D1 receptors.

(3) Enhancing glutamate activity at NMDA receptors might reverse negative and cognitive symptoms.

Blocking NMDA receptors by ketamine can induce psychosis, cognitive deficit. So maybe stimulating NMDA receptors can have the opposite effect.

#drugs and behavior #Neuroscience #my notes #study blog #schizophrenia #cw: medical torture #cw: medical abuse #cw: homophobia

6 notes · View notes

t0rschlusspan1k · 2 years

Text

I found out a man in my friends list who had an experience very similar to mine committed suicide while I was inpatient, two years ago. I think it was the exact day I entered the hospital. He had been institutionalised because he was paranoid, instead of curing him they only made him more insane and came out of the mental health facility utterly traumatised, on top of his paranoia. After 9 years he still had not recovered. They ruined him mentally and physically. Just like they did with me.

#cw: medical abuse #cw: suicide mention

2 notes · View notes

neuroticboyfriend · 8 months

Text

i know us schizos can be relatively lax about the word schizo... but for people who aren't on the schizophrenia spectrum, please remember... it is a slur, or at the very least, a derogatory term. maybe don't say it (unless we're okay with you calling us it), especially not to separate yourselves from us.

context: i just saw someone say "i'm not a fucking schizo" when talking about their misdiagnosis and resulting trauma. this could have been done without using a slur, especially given how much we also face misdiagnosis and medical/psychiatric trauma. we're in this together, not apart.

562 notes · View notes

medicalunprofessional · 4 months

Text

life is wasted

#psychonauts #caligosto loboto #medical abuse cw #<-yeah i think.That covers it #nightmaretheater #so sorry if you were innocently checking my blog after the crowment and were blasted with this #i was going to do a bit of artistic censoring but.Nahhh #time on canvas : 6 hours #i had to watch some videos of a transorbital lobotomy being preformed for refference 😁#god forbid i had my photos app open and someone looked over my shoulder and saw several screenshots #also Yes thats text from berenice. I cant be stopped #ohhh im so hungry.Chili for dinner……#wait. i forgot my watermark #thats okay. Theyll know its me from the berenice quote /nsrs #also yeah the orbitoclast looks a bit small. its the angle. Trust me. Okay.#I dont know how to paint flowers . I….Kind of my first time.Sooorry #Sorry guys . Had to post Horrifiying Upsetting Art again. Will continue to happen #its kind of funny this barely looks like fanart #good. Cant wait for someone to stumble upon this and freak out when they realize it is indeed fanart #surprised this was. 6 hours? Looks down at my hands… Woah…#reminder: I am drawing on my phone i did not go to art school💞#Okay time to collapse . Im really hungry #sorry . Just had to give my artists commentary

178 notes · View notes

vaspider · 1 year

Note

Dr Sidhbh Gallagher almost killed your friend??? I thought she was beloved by the trans community and her patients???

I'll let Rylan speak for himself.

#cw transphobia #medical abuse #medical neglect

823 notes · View notes

chrollohearttags · 6 months

Text

y’all gone jump me if I post this?

135 notes · View notes

autumnhobbit · 6 months

Text

They would have lost nothing in allowing this child to be treated. There was absolutely no reason to deny a request to help her. They did this willingly and without remorse.

God comfort her family.

#medical abuse cw #child death cw

139 notes · View notes

dajo42 · 2 months

Text

long post about substance abuse and addiction

the thing about me is i was dependent on alcohol for a few years and refused to admit it to myself forever until one morning when something clicked and i stopped but for the past three years its been... difficult. like. i still have dreams where im drinking but justifying it to myself like "this one doesnt count". i hate them

but im sober!!! and thats amazing of me

the other thing about me is i was also smoking whenever i could for a few years but also stopped doing that because i recognised it was another unhealthy dependency and... yeah the dreams happen with that too. the buying a pack of cigarettes and being like well these dont count these are a treat or whatever

but i still dont!! and thats also good!!!!

a third thing about me is for a while i was reliant on self harm to process feelings and i stopped that over a decade ago now!!!! thats so amazing of me

but

the most important thing about me for the sake of this post is that throughout uni i also developed an addiction to painkillers and would take numerous different kinds in dosages way above the recommended numerous times a day and it took a life changing conversation with a best friend in a train station for me to realise how unhealthy it was and how it was affecting people who cared about me to see me basically destroying myself like that

and thats

still ongoing!! i havent drank i havent smoked but i have at numerous points relapsed into full painkiller addiction and it fucks me up and my family still think i went to the hospital for food poisoning this time in 2022 but in reality i had been regularly near fatally overdosing for weeks

and its not like i can cut them out entirely because. they are prescribed to me for chronic pain. like. theres this painful line between taking the right amount to function and... feeling like i have to take more because i cant function without them. its like having an addiction to fucking.... water. i need it to live but its so often hard to tell if thats a real thought or if i think i need way more than i actually do in order to live and i fucking drown because the metaphor is about water

and right now i feel like im on the edge of relapsing again!! recognisable feelings and behaviours are creeping in!! and i dont want that!!!!!!

so im just posting about it on the internet i guess? to get the thoughts out of my head? to vent? to hold myself accountabld by screaming into the void? to ask for advice or reassurance? for somebody to tell me gently but firmly not to take more meds than i should. i took my normal dosage today. taking more would be bad and i recognise that but. i dont know. i dont know if i can trust myself not to tonight without being directly told not to by somebody who cares

#substance abuse #alcohol cw #medication cw #self harm cw

82 notes · View notes

doomspaniels · 1 year

Text

Folks

Gwyn's at the specialist

Tristan's Fetch and Tug Buddy carted her out of town so we could get her in sooner, try to figure this intermittent pain out, try to see why her bloodwork is Not Quite Right

and the specialist

thinks it's BEHAVIORAL.

🎉Behavioral🎉

Behavioral fake pain. Because it "shouldn't come and go."

She's a DOG.

This is her pain (the video I took as I was trying to determine where exactly it hurts, the pain is at her right side, last few ribs). Sound on.

#vet visits #cw medical abuse #incandescent fury

257 notes · View notes

slowandsteddie · 1 month

Text

Lazy Petals

AO3

Okay. This work is NOT completed. I cannot guarantee an update schedule because only the first chapter is completed. However, I DO have everything plotted out (assuming it doesn’t get a mind of its own) and the goal is to be 50k+ words.

This story is very personal to me. I’ve taken my grandparents love/live story and made it Steddie. The characters are going to be OOC. Just letting you know right off the bat in case that is something you aren’t interested in. Also, this is a No Upsidedown AU.

My grandparents were immediately obsessed with each other, but didn’t date until after they had graduated high school. Which means that while this isn’t a slow burn, it is going to be slower than the stuff I usually write.

I don’t want to give too, too much stuff away. There there is a post where I described the main highlights and asked your opinion on reading it. There is also a poll where I asked if I should start posting before it was finished, and I got a pretty definite yes.

I saved the divider that I plan on using for this series back when I first started talking about it. I have since lost my note that told me whom to give credit to. If you know who made it (or know how to find that information on mobile!!) please let me know.

I think that’s enough of a preamble. Without further ado, here be the CW’s and the first 3,489 words.

Content Warnings: Steve was hit by a car and in a full body cast for over a year - he makes a bowling joke about it, his parents are very distant, his grandparents got very distant after his injury and he doesn’t understand why, Wayne is very careful while babysitting to make sure that no one can accuse him of being inappropriate, mentions of his mom overmedicating him so he’s easier to deal with, mentions of how weak he got from being in the cast. And as always, let me know if I missed anything.

Steve didn’t remember much about that night.

His mother said that it was a blessing and refused to fill in any blanks for him under any circumstances.

His father, however, if he had drunk enough whiskey, would look at the six year old Steve as though he were a much older man and sigh before telling him anything he wanted to know.

Which meant that Steve knew that the car that hit him swerved in order to do so. (He didn’t know if the lady in the little blue car did it on purpose, or if she was a distracted driver. He wasn’t sure if he wanted to know that.) He knew that she had to have been going over forty miles per hour because the impact sent him flying at least a dozen feet before he slammed into that bus stop. He knew that the driver kept going and that at least half a dozen people ran to his aid and that one of the women had screamed because he was unconscious and she was so certain that he was dead. His little body was so broken and bloody and they couldn’t see him breathe.

He also knew that his father got to his hospital room before his mother, sweat pouring down the older male’s body as though he had showered in his clothes because he had run there from work. His mother showed up over twenty minutes later, all put together like she had taken the time to clean herself up before appearing. Something his father wasn’t sure if he could forgive her for. (This was one of the few times that his father would express just how much that he loved Steve, and he would carry that warmth with him forever.)

He knew that they had to revive him four times, that they had done twelve surgeries, that they had put him in a full body cast because nearly every bone in his body had been broken, including parts of his spine. He knew that his parents had been told that he would likely never walk again. He knew that a specialist had pulled his father aside to inform him that his brain wouldn’t develop normally after all of the trauma that it had been through after being smacked around in his skull. They’d have to be careful, and that they’d have to understand if he never progressed much past the age that he was now. That he could be in his fifties and still acting five and that there was nothing that could be done beyond what they had already done – remove a small part of bone behind his ear to help relieve the pressure and pray for the best while preparing for the worst.

And, while he couldn’t remember the absolute agony that he must have been in. He did have the descriptions that he used to tell his father. That there was lava in his veins and his bones were shards of ice cold glass threatening to tear him apart completely. His father had only told him that part once, with tears in his eyes. “There wasn’t anything I could do to help you, boy. I couldn’t take the pain away. I would have died to save you even a fraction of that.”

That was one of the few times that he could remember his dad hugging him. He had been so careful and gentle while pressing his face into his hair. He inhaled deeply and he cried. And Steve had done his best to hug him back despite the plaster that made it near-impossible to move his arms at all.

At first, Steve had thought that it was really cool to be stuck in bed all the time. He didn’t have to do anything. That got boring within a week and he still had at least a year ahead of him where he was meant to stay in bed unless he was in the bathroom or at a doctor’s appointment.

Even eating in bed, something that had once been unacceptable and even punishable before, lost its novelty pretty quickly.

He liked having his mom read him notes from the teacher and his classmates. He liked her reading him his homework assignments and writing down his answers for him so that he would still be on track. It made him feel like an important man, like his dad was going to be, with a secretary.

The thing is, though, that he really missed going outside. He missed playing in the woods outside of the trailer park where he lived. He missed going to his grandparents house with the pool and the stairs that he’d probably never be able to walk again. He could climb them, though, after the cast was removed. He was pretty sure. He might not have a lot of muscle left at that point, but that would just mean that he was lighter and had less to have to move anyway.

When Steve brought that up to his mother, her lips would turn into a very tight, thin line and something he couldn’t name would flash in her eyes. “You are not going to go to that house any time soon, young man. It’s best to let those ideas go.”

“But I miss Grandma Marty and Grandpa Pete, and they won’t come here,” he whined.

“The Harrington’s won’t come to the trailer park and you know that.”

“We’re Harrington’s too,” he’d say defiantly.

She’d leave the room at that. Effectively ending an argument that they had had multiple times before. But what else did Steve have to talk about? He didn’t really have anyone else to talk to either, other than their neighbor that he had taken to calling Mister Wayne.

Wayne was probably a few years older than his dad and lived alone in a trailer that had always seemed so lively despite the quiet man who lived in it. He always had the tv or the radio on when he was home and Steve lived for that. Because his window was always cracked open for the breeze, which meant the sound could drift to him as well.

It was better than the quiet of his house that only seemed to get broken up with arguments and slamming doors. He was so used to it, but he still flinched every time and did his best to pull the blanket over his head as though that would muffle the sounds.

Sometimes, Wayne would come to his window and read him a book that his own nephew liked. The Hobbit. Steve fell in love with the adventure of it, and Wayne never seemed to mind reading him the same book over and over, a few pages at a time while he smoked.

More often than not, Wayne was the one who came over to babysit once he noticed that Steve had been left alone. He never once complained about it, never once gave someone else the chance despite all the ladies who would come over with food. And wine for his mom, when they could spare it.

Sometimes, Wayne would talk about his nephew. He was a scrawny kid, a few years older than Steve, named Eddie. Had a dark mop of long curly hair, and eyes that always seemed to have mischief in them. They’d like each other, Wayne was pretty sure, and he’d introduce them the next time that Eddie came to visit.

Steve would want to ask when that would be, but he never did. He had Mister Wayne and that was more than enough for him. His dad was staying later at the office, trying to prove that he deserved that promotion that would get them the hell out of the trailer park, without his parents' money. His mother was getting into yoga and book clubs, and Steve was being left alone a lot. Because, what kind of trouble could he get into when he was stuck in bed? Besides, the neighbors could hear if he shouted for anything and Wayne seemed very invested in making sure that he was okay.

Steve never knew why the older man made sure that his curtains were always wide open and that his light was on so that others could see that he was reading to him, or talking with him, from a chair that was always at least three feet away. Maybe it was so they would know he wasn’t alone? He wasn’t going to ask about it, not wanting to chance scaring away the one adult who never raised his voice at him, who never abandoned him when things got hard like his grandparents seemed to.

Months went by like this. His parents not being home, his grandparents not even calling about him, and Wayne doing his best to fill in the difference despite his own job. The other neighbors would come on occasion, but Steve was very sullen with them where he would laugh with Wayne. That didn’t deter them from coming over as he would have liked, and begrudgingly he found himself becoming friendly with a few of them.

It was the beginning of summer when Steve was finally able to get the casts removed. His father took him to the appointment, and he tried to not be disappointed that his mother wasn’t there at first. By the time he was wheeled out to the front of the office, though, his mother was sitting where his father had been.

He did his best to not look at himself. He was pale and scrawny and kind of stinky from not being able to wash himself properly because of all the plaster that had basically covered him for over a year. Most of his bones had healed great, according to the doctor. He wouldn’t know because he still hadn’t looked.

His father came back from wherever he had been, paid the bill with tight lips, and then took Steve out to the car. His mother helped him into the seat before covering him with a blanket that he was grateful for. It wasn’t that he was cold, he just didn’t want the chance to look at himself yet. He wanted to do that when he was home, where if he broke down and cried, no one else would know. Or, he wouldn’t have to see them knowing in any case. And that was enough for him.

They stopped for ice cream on the way and Steve asked for a small strawberry cone. Strawberry wasn’t his favorite, but it was what Grandma Marty had all the time, and he missed her even though she didn’t acknowledge him anymore. Wouldn’t answer his calls, wouldn’t call him back. He didn’t even know if she got the letters that Wayne had helped him write.

When they got home, Wayne wasn’t home. Not for the first time, Steve found himself deeply upset by that. He’d never voice it. Adults had responsibilities outside of him. And he knew that he only got about an hour with Wayne a day, maybe two if he was incredibly lucky.

His father came to help him out of the car, because he had more muscle if Steve should happen to fall. He clung to his father’s arm with all the strength that could muster as he walked like a baby giraffe toward their trailer. Well, he called it walking. It was more like wiggling his lower spine and hips while throwing his legs forward. After maybe five steps like that, he found himself being lifted into his father’s impatient arms as he was carried the rest of the way in and sat on the couch.

“Thank you,” Steve said instead of complaining about not being able to use his legs. He had wanted to walk, to prove that he could.

His father simply grunted in response before going to the kitchen to grab a drink. The same way he always did when he was home for the night.

His mother was inside a few minutes behind them, having stopped to talk to a neighbor briefly. She looked at Steve on the couch and tilted her head at him with a calculating look in her eyes.

“Would you like a bath?”

“Yes, please.”

This time, Steve did get to walk on his own two feet to the destination. He was leaning heavily on the wall, almost gripping on to it with one hand as he practically threw himself forward. He was breathless by the time that he got to the bathroom and pain seemed to radiate out through his entire body, starting at his tail bone.

“You can have some meds after your bath,” his mother said gently. “And I’ll get you your refill before dinner, okay? So you don’t have to worry about running out.”

Steve didn’t think it was time to refill his medicine yet, but he didn’t question it. His mom was on top of it. He was a kid who lost track of time a lot.

He sat on the toilet and he watched his mom prepare the bath for him, knowing that she would only let him have the water a little above room temperature. His skin was sensitive and the steam wouldn’t be good for him with the medicine that he was taking. He couldn’t even have hot food without the steam making him nauseous.

Carefully, he was pulled back to his feet and stripped of his clothes before he was helped into the tub that seemed to be more bubble than water. He sat down carefully, wincing a bit as he did so, before letting himself lean back in the water that felt warmer than it probably was because of his weakened, cool skin.

He sighed in contentment as his mother washed his body for the first time in what seemed like years. He was nearing seven years old and thinking about years in the past, it would make his dad laugh if he shared that thought with him, an idea that made him smile.

His mom washed his hair, tilting his head back and using a hand to make sure that no soap got in his eyes that he had squeezed tight. He got to play in the bubbles for a few minutes, his dad standing at the door as his mom got him some comfy clothes and a towel.

It was his dad who dried him off and helped him get into his clothes.

“Thank you, Daddy,” he said softly. He knew he was expected to thank his dad for everything he did that was above and beyond, which meant he ended up thanking him for everything.

Steve was carried back to his bed, something that he would have whined about if he wasn’t so tired and in so much pain. He was tucked in and his mom came to give him some toast and juice to take his pills with. He knew he was only meant to have one, but he took both that his mother gave him anyway. He washed it away with grape juice and half of the slice of toast she had brought him.

“Thank you, Mommy,” he murmured.

“Get some rest, love,” she replied while kissing his forehead. “You had a big day today.”

Steve nodded in agreement, wishing that it could be that easy to just let the sleep overtake him. He closed his eyes as his mom left the room.

His father checked on him once a day, his mother gave him two pills instead of one, and made sure he at least had breakfast and dinner. One of the neighbors made sure he had lunch and new puzzles to work on, new toys to play with. Steve would wander around the trailer as best as he was able, and Wayne would read to him before he went to bed.

Days turned to weeks like that.

One day, Wayne wasn’t at work and both of Steve’s parents were gone. He wandered over to his bedroom window and opened it wide.

“Mister Wayne, if I can get to the front door, can you help me out?”

His walking was still unsteady and stairs were very difficult for him.

“Are your parents okay with you being outside?” Wayne asked sympathetically.

“Uh. Dad said I could as long as I either finished my puzzle or put it up first.”

Wayne gave him a knowing look. “Okay, you little hellion. But only because I know you’d hurt yourself trying to do it anyway.”

Steve beamed and closed his window most of the way before making his way to the front door. It was a struggle to unlock the door because of the latch chain, but he managed. Wayne was waiting there for him with an unlit cigarette hanging between his lips.

“Getting outside used to be easier,” he sighed before reaching out.

“Maybe it’s the weight of knowing that you’re doing something you shouldn’t be,” Wayne teased as he picked Steve up and set him back down on the ground.

“No idea what that means, but thank you for helping me pass the stairs.” Steve grinned widely, the dirt and grass squishing slightly beneath his toes. It felt so good.

“You’re welcome, brat.”

Steve giggled before doing his version of walking. He took maybe ten steps, very much aware of how closely he was being watched. His breath came a little harder from the effort, the times between walking so close together. Shakily, he sat down as carefully as he was able. Movement caught his attention and made his head snap up to look toward Wayne’s trailer.

“You gotta ghost!” He exclaimed.

Wayne laughed at that, shaking his head. “That’s the nephew I’ve been telling you about. He’s staying with me for awhile. Treat him like a skittish cat until he’s used to ya, and I’m sure y’all would be good friends.”

“Eddie,” Steve said happily. “Can he come out so I can meet him?”

“I’ll send him out after I smoke my cigarette,” he said as he put more distance between them before lighting up.

“Thank you!”

Steve laid down flat on the grass, spreading his arms and legs out as much as he could without the pain becoming unbearable. It wasn’t very far, but he didn’t care. He got to grip the green strands in his fingers. He got to feel the light and heat of the sun soaking into his skin and settling into his bones. He was beyond convinced that the bright yellow thing in the sky was much more healing than the meds that made him feel tingly from his head to his toes.

He must have fallen asleep like that, because next thing he knew he was being awoken by a toe nudging his shoulder. His eyes flashed open and he was met by the most dark, beautiful brown eyes he had ever seen.

“Uncle Wayne said you just got released from the mummy’s curse.”

“He said that?”

“Well. He said your name was Steve and you just got a full body cast removed a few weeks ago.”

“That sounds more like him.”

“So…What happened?”

“A lady tried to go bowling with me and her car. The only pin she knocked down was me.”

Eddie snorted. “Shoulda planted your feet more firmly, she woulda gotten a strike.”

Steve’s lips tugged into the widest smile that he had ever had on his face. “My parents don’t like it when I joke about it.”

“Parents are stupid.”

“Yeah. How long are you stayin’?”

“As long as I can.”

Steve hummed in thought. “You any good at reading out loud?”

“Depends. What book?”

“The Hobbit.”

Eddie’s entire face lit up, his huge smile showing off the chipped front tooth. “My favorite book in the entire world? Yeah, I’m pretty good at reading it out loud.”

“We should read to each other. I have troubles with some words, but I am trying.”

“I’d like having someone to read and play with.”

“Oh, uh. Playing is hard for me right now. I’m still trying to get my strength back.”

“It’s okay. We read The Hobbit, we gotta have a pretty good imagination. We can pretend to play.”

Steve blushed and looked away. He never had someone his own age willing to work around his limitations before.

“I heard about a game with dice where we can talk out stuff and the dice decide how well it goes,” Steve said suddenly.

“Dungeons and Dragons!” Eddie apparently decided that he was tired of standing because he flopped down next to him at that. He rolled around in the grass before eventually settling on his side, propping his head up on his hand. “I can find a way to make that work with just two people.”

“Oh.”

“Turn that frown upside down, friend. I like a challenge. We’ll make this work because it sounds like fun.”

Steve beamed.

Taglist (let me know if you want added or removed! I was just trying to get who I remembered to seem interested!):

@estrellami-1 @eriquin @epiclazershark @morganski-19 @ellaelsinore @y4r3luv @valinwonderland @thespaceantwhowrites @jackiemonroe5512 @spectrum-spectre @princessstevemunson @ghost--enthusiast @gothwifehotchner @kas-eddie-munson @auroraplume @salisbury-at-the-stake @currently-steddiebrainrot @finntheehumaneater @marshmellowpaint @littlewildflowerkitten @perseus-notjackson @sapphirecobalt-1 @xxfiction-is-my-realityxx @gloomysoup @anne-bennett-cosplayer

#stranger things #steddie #steve harrington #eddie munson #steve stranger things #eddie stranger things #steve x eddie #taking my grandparents love story and making it steddie #grandparents love story #lazy petals #no upside down au #read the cw #car accident aftermath #mention of medical abuse #let me know if i missed anything

49 notes · View notes