#cw tumor
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Teratoma
#cw body horror#cw tumor#teratoma#tumor#tumour#cw tumour#pixel art#pixel artist#pixel horror#horror art#body horror
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Nothing really distracts me from the fact my mother got cancer and our old dogs tumor getting so bad she starts having seizures. I act all cheery or some bullshit but i am not well. At least my mothers cancer is very well treatable with a 96% chance of no regrow. But i am not prepared to coming to my parents home knowing i cant be around my old lady and comfort her until the end. But i just can't leave with two jobs. And i am holding it together for the kids i am looking out for right now. But i haven't slept a lot lately and my health is bullshit as well so i just dunno what to do. Distraction only works so much.
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Pic from my old college campus, reblogs appreciated
—
ko-fi
neocities
artfol
#stoner art#punk art#punk#punk aesthetic#digital art#tapeworm#cw tumor#tumors#unreality#cw unreality
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Well I just spend a good amount of time lying in the dark on the floor next to my cat, while also crying and almost sobbing out loud. But it was in that weird depressed way of crying. Like aftershock before the catastrophic event even happens. Where if I took the time to think deeply about it, I would bawl. But if I looked at my surroundings, I would instantly stop crying and feel nothing again. Almost as though the crying never happened
I remember hearing about that kind of on-and-off grief in one of doodlevloggle’s videos on YouTube. I think she discussed it briefly in “yeah ow (sept)”. But I’ve never experienced it before until now. Perhaps it’s a sign that my depression might be more that moderate at this point…
According to this source I found, the lack of feeling emotions (mainly that of happinesses) is called social anhedonia? Often associated with depression, social anhedonia causes a lack of ability to feel pleasure when engaging in social interactions. You often feel the need to fake emotions, since your feeling of enjoyment is unresponsive/diminished. This often results in social withdraw and lack of care for your loved ones. That would explain why I feel so detached from emotions and social situations, finding myself zoning out all the time. But I’m not sure if that term is dated or not. And it doesn’t have any correlation to the on-and-off crying, so I’m still not sure what that’s about
But this isn’t mean to be about depression terms. This is about spending time with my cat. Maybe the final moments I’ll get to have with her aside from the brief moments tomorrow. Yesterday I was able to get her to purr again when I pet her, but tonight she was silent. It’s unreal how quiet she’s become, when just last month she was still her talkative self. I don’t understand how things changed so quickly, and why my parents faced such sudden urgency with putting her down. They say it’s because (even though we received medication for Nia last week, so we haven’t even given it enough time to determine if the effects work in the long run) the medication only helps numb her pain rather then help her get better. It’s not going to help heal her, and her condition has already debilitated her and can’t be reversed or stopped from growing. I don’t think I’ve come to terms with that idea, what do you mean we are just giving up on her? I know logically it makes sense to put her down before things get worse and the pain becomes unbearable, but…I don’t want to say goodbye. I don’t want to feel like I’m giving up on the chances she could recover (even though it’s impossible with her tumors)
As I’m writing this its getting late, but I don’t want to go to sleep. Because that means I’ll wake up to see tomorrow. When my cat (Nia) will be put to sleep. And I’ll have to bear witness to it. And I’ll most likely feel nothing…and that would kill me internally. I’ve been so disconnected from this situation ever since the news plagued me last week. And I don’t like how unemotional I am about this terrible situation. I should be feeling terrible. But I’m not. Even though I grew up with this cat, even though her brother already died so now that she’s gone we won’t have anymore cats around. She’s the only sister I’ll ever have. And yet….I don’t feel like I’m feeling anymore or any less then I did weeks prior. It makes me seem as though I’m being dismissive to the severity of the situation. I’m NOT TRYING to be. If I could, I would choose to feel all the sadness and pain that comes with experiencing death. Even though it’s awful to feel those things, at least I’d know I actually care. That her death holds significance to me. Maybe then I wouldn’t think I’m so cold or emotionally broken
I want her to know I love her, and that I will miss her. I want my family to recognize that I share their grief. But if I don’t shed any tears, or feel sad for days on end, how can they know? The last thing I want is for my Dad to question me about it. Ask stupid things like “don’t you feel bad about it?” when that’s a given already. I know he doesn’t mean ill by phrasing words like that. But last week, he wouldn’t stop shoving the older photos of Nia in my face and saying “this is how she looked in her prime” when he knows I was THERE. I already know that she has been suffering recently. I know she was in better health when she was younger. It’s almost like he thinks I have a terrible memory and forgot about it?? I know that my attentiveness has been lacking because depression, but that doesn’t mean I have a faulty memory. It seems like, by mentioning Nia’s condition over and over, he wants an emotional reaction out of me…some acknowledgment or confrontation that I feel sad about it. Or perhaps it’s just his own way of grieving and coming to terms with how things are in the present. I know it must be really hard for him, being reminded of Niko’s passing while also loosing Nia. Both of them had tumors which spread throughout their bodies. And now Nia is going to be put to sleep tomorrow as well. But at least this time, we will be there for when she passes. I’m terrified if witnessing her go limp and stop breathing. This is the first time I’ve witnessed death in person, despite having been surrounded by it in the past
And I hate how I’m making this all about me and my parents rather then Nia. The center of all of this. Maybe later on I will write a proper memoir/tribute to her life, and give her death the significance, compassion, and respect deserved. While remembering her life and reminiscing on how many memories we shared. But as of now I don’t know what the proper corse of action is. I still haven’t even written a proper goodbye for my cousins passing. I don’t know if I’d be able to write such an emotionally charged tribute without lacking. I get that it’s the thought that counts, but even so, I don’t want to be doing it for the sake of doing it. I want it to come from genuine heart and give myself time to compose my thoughts in a meaningful way. So most likely I’ll hold off from it
It makes me somewhat anxious how I’m only a few more hours away from tomorrow. Only a few more hours away from a final goodbye. And still, even after writing all of this, even after crying on the floor next to Nia and petting her fur, I remain unmoved. Resistant to accepting reality. So detached from the situation that I don’t know how I’m meant to react. I’m scared. Terrified even. None of this feels real. I hate goodbyes. I hate how incomplete all of this feels. And yet again, I made it about me. Fuck
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"In a first-ever human clinical trial, an mRNA cancer vaccine developed at the University of Florida successfully reprogrammed patients’ immune systems to fiercely attack glioblastoma, the most aggressive and lethal brain tumor.
The results in four adult patients mirrored those in 10 pet dog patients suffering from brain tumors whose owners approved of their participation.
The discovery represents a potential new way to recruit the immune system to fight treatment-resistant cancers using an iteration of mRNA technology and lipid nanoparticles, similar to COVID-19 vaccines, but with two key differences: use of a patient’s own tumor cells to create a personalized vaccine, and a newly engineered complex delivery mechanism within the vaccine.
“Instead of us injecting single particles, we’re injecting clusters of particles that are wrapping around each other like onions,” said senior author Elias Sayour, M.D., Ph.D., a UF Health pediatric oncologist who pioneered the new vaccine, which like other immunotherapies attempts to “educate” the immune system that a tumor is foreign.
“These clusters alert the immune system in a much more profound way than single particles would.”
Among the most impressive findings was how quickly the new method spurred a vigorous immune-system response to reject the tumor, said Sayour, principal investigator at the University’s RNA Engineering Laboratory and McKnight Brain Institute investigator who led the multi-institution research team.
“In less than 48 hours, we could see these tumors shifting from what we refer to as ‘cold’—very few immune cells, very silenced immune response—to ‘hot,’ very active immune response,” he said.
“That was very surprising given how quick this happened, and what that told us is we were able to activate the early part of the immune system very rapidly against these cancers, and that’s critical to unlock the later effects of the immune response,” he explained in a video (below).
Glioblastoma is among the most devastating diagnoses, with median survival around 15 months. Current standard of care involves surgery, radiation and some combination of chemotherapy.
The new report, published May 1 in the journal Cell, is the culmination of seven years of promising studies, starting in preclinical mouse models.
In the cohort of four patients, genetic material called RNA was extracted from each patient’s own surgically removed tumor, and then messenger RNA (mRNA)—the blueprint of what is inside every cell, including tumor cells—was amplified and wrapped in the newly designed high-tech packaging of biocompatible lipid nanoparticles, to make tumor cells “look” like a dangerous virus when reinjected into the bloodstream to prompt an immune-system response.
The vaccine was personalized to each patient with a goal of getting the most out of their unique immune system...
While too early in the trial to assess the clinical effects of the vaccine, the patients either lived disease-free longer than expected or survived longer than expected. The 10 pet dogs lived a median of 4.5 months, compared with a median survival of 30-60 days typical for dogs with the condition.
The next step, with support from the Food and Drug Administration and the CureSearch for Children’s Cancer foundation, will be an expanded Phase I clinical trial to include up to 24 adult and pediatric patients to validate the findings. Once an optimal and safe dose is confirmed, an estimated 25 children would participate in Phase 2."
-via Good News Network, May 11, 2024
youtube
-video via University of Florida Health, May 1, 2024
#cw cancer#cw death#cw animal death#medical news and technology#cancer#brain cancer#cancer treatment#tumor#brain tumor#florida#university of florida#medicine#biology#cell biology#mrna#mrna vaccine#vaccines#oncology#good news#hope#Youtube
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Short preface:
I like to learn different sorts of new things about medicine and how interesting diseases or injuries can be. And one day I came across a post about melanin and cancer. Melanoma can appear on skin or on any mucous membrane. Even in eyes. An eye cancer called eye melanoma. A tumor originating in one particular part of the eye, in the absence of any action, completely affects the eyeball, causing it to turn black. And this type of disease reminded me of Kevin!
So I present you my headcanon: Kevin's eye melanoma.
(In addition, if we imagine that in such an extreme stage of infection, Kevin miraculously remains alive (and unknown in any way to science can see). So: he may also has a mild form of exaphthalmia (bug-eyed), lack of peripheral vision and bad vision in general)
Bonus:
Small fast sketch bc why not. (Sorry for my bad handwriting lol)
#art#welcome to night vale#wtnv#wtnv kevin#kevin#wtnv carlos#carlos the scientist#wtdb#wtdb kevin#sketch#interesting fact#Moles and melanoma are two different things#despite the presence of melanocytes in both cases; one is a malignant tumor and the other is just a harmless cluster of cells#medicine#I love science facts#cw blood#wtnv headcanon#headcanon
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Hey guys, if you could pray for me and my parents I'd be really grateful. The last cat in our old brigade, Tansy, is almost 15 and at the end of her days. She tends to get sick from allergies during the spring and she's had a rough winter and she's just, she's not going to make it through this time and she's been SUCH a good cat her whole life that we're not gonna let her suffer through it to the end. We're hoping we can get an appointment to get her put down tomorrow (that sounds awful saying it, but she's miserable and I can't watch her suffer she doesn't deserve that), so we would really appreciate your thoughts and prayers.
#cats#tansy#tw pet death#cw pet death#the only good(?) thing about this is that it's not sudden like baby tulip#I have known this was coming and been preparing for it mentally for months now#she took a turn for the worse today tho despite all our efforts to help her keep going#I *think* she might have a tumor in her cheek that suddenly got very malignant#she has a lot of the symptoms#and I think that + the allergy sickness she usually gets is just too much for her#but she has lived a GOOD life#and she KNOWS we love her#she is INCREDIBLY intelligent#she's sid's adoptive mama#like she straight up adopted a stray half-grown half-starved kitten#and TRAINED IT#to be her friend a hunter and a guardian of our home#she literally taught sid everything he knows#I'll post a little memorial for her when she does pass with pictures#because she has such unique and beautiful coloring#she's a torti#and SO sweet#she is literally one of the best cats we have EVER had#I'll miss her terribly <3
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Hi. So. On one of the first Big Adult Holidays, me and a group of my oldest friends went to a spa for my friends' 20th. Said birthday girl was called Emma and was one of my absolute favourite people. Totally insane, mad as a box of frogs. Well we open the first room – of the SERIOUSLY nice hotel which at that point was the greatest kind of novelty that we all had scraped by to afford – and Emma, delighted, wooped, and from the door ran and *launched* herself to belly flop down on the huge and decadent bed in the room in celebration. Except, she completely overshot the bed somehow, and so the picture was a girl wooping, running and then throwing herself like a drunk Olympist over the bed and completely disappearing from view with a cartoonish thud. It is still, to this day, one of the most hysterical things I have ever seen, and one of the biggest laughing fits I think any of us have ever had, especially Emma. My knees gave out and I had to crawl on all fours to go around the bed to see if she was OK because I couldn't breathe enough to speak. And there we lay for an age trying to stop laughing.
On this day in 2018, a few days before her 25th birthday, Emma passed from a brain tumour. I miss her every day, but this story still is the one anecdote we can tell and always still laugh, without fail, even today.
Miss that stupid sod. We were complete fucking idiots together.
#grief#i just wanted to tell you about her#er#tumor mention cw#helen speaks#i never do this ever but idk. i feel very thinly spread today i guess
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𝐉𝐞𝐫𝐦𝐚 𝐐𝐮𝐨𝐭𝐞𝐬 𝐒𝐞𝐧𝐭𝐞𝐧𝐜𝐞 𝐒𝐭𝐚𝐫𝐭𝐞𝐫𝐬
Some out-of-context quotes from Jeremy himself, change pronouns as needed!
"You little shit, it's not a tumor, okay? I'm gonna strange your parents!"
"No one should ever put cigarettes out on their penis...for any reason."
“Get!— There’s Blood in the box, there’s blood inside this box.”
"Yeah- I have- I am- I'm... I'm just thinkin of the explosion from, like, three weeks ago"
"Would you smoke a blunt with Peter Griffin?"
"I don't wanna turn on the light and fuck up my cones and rods"
"[Name]... I would rather... I would rather be naked on camera than play League Of Legends with you for an hour."
"Feed him to the lions."
"They saw me. Uh, having sex. Uh, with Death. In my bed"
"In fact, yeah, you're gonna get punished with a Stewie Griffin impression"
"See you motherfuckers are gonna think this is funny."
"Oh ya, ya, ya! No, no, no, no, no, the thing in the fridge is definitely not human meat..."
"I am The Rats... The Rats are NOTHING with out me"
"Everyone's gonna do the "small penis" curse to me."
"He's made out of the goo that I shoot out of my staff."
"But I don't- I don't- I- I- I refuse to believe that this is an un-pog moment right here"
""You cant count worth shit" I can piss my pants though"
"Underwear is stuck to my ass right now... and its gonna take a God- its gonna take a god damn crowbar to get it off"
"I'm not actually saying that I'm going to put somebody in a meat grinder, goddamnit. Whatever."
""You're built like a truck" I know, my ass is huge, I know"
""Would you ever have kids?"... No, I've shit my pants in the last year. I can't handle it. I wouldn't be able to do it."
"I don't- I like, don't know what that is but I kinda do. I don't know what that means. I don't know why I read that."
"I feel- Sometimes I feel like you guy's mother at dinner"
"Please, I'm wicked high, what are you doing?"
"Don't worry, I-I-I'll bring myself down a few PEGS, uh, when I do the catboy stream, right?"
"I'm about to sneeze again... I didn't even sneeze once today... Why did I say "again"?"
"gahd... Fuckin' fire ants everywhere... I'm gonna die from fire ants"
#rp meme#sentence starters#cw; drugs#cw; blood mention#cw; tumor mention#there will probably be more but for right now-
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i just found a lump right at the base of peach's throat. it was his 2nd birthday like 2 days ago. he's been so so skinny recently and no matter how much we feed him he just won't put on weight and i just found a lump at the base of his throat.
#personal#keeping it fun and funky fresh#the wild brunch#i cannot fucking cope with this. i cannot#peach is My Baby. he's my heart rat. he's my darling boy. i've never felt this way about an animal before#his brother benny died of a pituitary tumor a year ago (fuck. was it only a year??)#and his other brother lunchbox literally JUST had his tail amputated bc of what we thought was a huge cyst a third of the way down#ended up being a tumor too#(lb is recovering well as far as we can tell)#i believe All of his sisters have died. and i know his other two bros died ages ago#our friends adopted a pet store rat who turned out to be pregnant so they are decidedly not of controlled breeding#i'm so so upset tho#my baby boy. my peebs my peebles my peach bellini my lil nakey man.#pet death cw
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Got my MRI results back, it's not terrible I guess but it's also...not great. I'm pretty unhappy actually. I was really, really hoping for more shrinking. But while the giant one in the left lobe has shrunk a little bit more, the biggest one in the right lobe has grown! It's now 8.4 cm x 6.7 x 7.1 cm, when before it was only 7.6 x 6.1 x 6.4. I'm really devastated that one has grown, I don't exactly know what that means for me but it's not good! And I remembered that I have a LOT of tumors, like, a lot, because when I looked at the scans last year honestly my liver looked like it was more tumor than liver. But I had kind of convinced myself that maybe I was exaggerating that in my head and actually only had like 6 or 8? But the report says "The lesions are too numerous to count [much greater than 10]." So it was how I remembered it, lots and lots of large tumors everywhere. Bc technically anything greater than 5cm is fairly high risk/often operated on, and I have several that are bigger than 5cm. But they can't operate because there are too many and so it's pointless/they can't remove enough of the liver safely. And now some are growing and even if some are shrinking they aren't shrinking much. The overall impression was that this scan was "similar to prior." Which is better than significantly worse but I was really really hoping for better news. I'll have to set up an appointment with a hepatologist to really discuss the results but...at first glance this kind of sucks.
#text post#my post#at least my unrelated blood work looked good. my cholesterol and vitamins and stuff is better#but yeah. this sucks.#i can't believe one of the big ones grew. idk what that means but i'm a bit freaked out about it#and it just. sucks that there are so so so many#the images really do look like my liver is at least 75% tumor when you see them it's wild :(#and by wild i mean kind of terrifying#medical cw#medical tw#hepatic adenoma#hepatocellular adenoma
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Quin were you on gaiaonline back in the day
Got back into my account after years and it’s very nostalgic
Gonna go see if I can find some of my old RPs xD
Oh my goodness. Gaia Online.
Man. Throw back Thursday indeed.
Very tangentially Gaia just about saved my life.
I met some friends there, who I don’t talk to anymore - such is the way of life - but they gave me enough support that I went to Planned Parenthood for an issue (constant bleeding, not a pregnancy concern) when I didn’t have health insurance and no one else would even see me.
PP found a tumor, and I got surgery, and I only went because my friends on that website convinced me to go.
I had a massive tumor removal surgery - so big my organs were starting to shut down from the pressure.
So, I mean, when I say online friends are real friends, I’ve believed that for decades. (This was 2005/2006 somewhere in there).
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techno tattoos are completely okay and good 💛
in fact mrtechnodad himself is getting one :)!
x
#mr technodad#mrtechnodad#technodad#mrtechnodad reddit#mrtechnodad updates#technoblade#mr technodad reddit#subscribe to technoblade#r/mrtechnodad#technoblade never dies#tw technoblade death#cw death#cw cancer#tw tumor#techno tattoo#tattoos#tattoo#agro pig#memorial tattoo
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my mom’s cancer did come back, but the prognosis is really good. they had been monitoring a spot on her scans and when it got bigger, they scheduled a biopsy.
there is a strong possibility that she will not need chemo after her surgery.
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“A rogue protein that fuels the deadliest brain cancers has been identified by scientists in a breakthrough that opens the door to bettering what is normally a 10% survival rate.
The scientists used gene editing to deactivate the protein, which stopped the tumor growth in its tracks—a hugely encouraging sign.
Glioblastomas have one of the lowest survival rates of any cancers, with fewer than 10% of patients living past 3 years.
“The aggressiveness of glioblastoma is notorious,” said the new paper’s lead author Professor Alea Mills. “The norm is to do surgery, treat with harsh drugs and just hope for the best.”
Mills and her team identified an Achilles heel of glioblastomas, which not only could lead to better treatments, but also explain in part why they and other cancers are so aggressive.
Bromodomain-containing protein 8, or BRD8, was found to suppress the activity of one of the most important cancer-preventing parts of a cell, the P53 gene. P53 codes for proteins which stop cells dividing when they should otherwise die, and almost all cancers depend on disruptions in P53 activity or production.
In experiments the researchers deactivated BRD8 using a pioneering gene editing technique. Without overactive BRD8, the P53 proteins coded normally again, and the tumours, transplanted into mice from human patients, were stopped in their tracks.
When BRD8 was deactivated, P53 was unlocked—the tumors stopped growing and the rodents lived longer.
The findings in Nature suggest drugs targeting the heart of BRD8 could work against glioblastoma.
Professor Mills hopes it will help turn deadly brain cancer into a treatable disease, dramatically extending life expectancy of patients.” -via Good News Network, 12/23/22
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