Tumgik
#clinical medicine
the--chaos · 9 months
Text
Tumblr media
🥼🩺
73 notes · View notes
tmedic · 1 year
Text
Tumblr media
#new essentials .. 🖤
65 notes · View notes
myscrubslife · 2 years
Note
Hi, you’re blog is super inspiring and I love to go through it! I was wondering how one can keep such good focus or if it’s just natural to you? I suffer from bipolar and adhd and my focus is so horrible but I’ve always been in love with the medical field. To be a nurse or even phlebotomy seems difficult! When did you first realize you wanted to be a doctor?
That’s so nice of you! 😊 I started this blog to combine my love for art and medical sciences.
When I was about 5, my grandpa had a major heart surgery (CABG) that was my first exposure to a big hospital. My dad’s company used to do volunteer work with paediatric cancer patients and I used to go visit with him. Over the years I saw more of my grandparents go in and out of hospitals, met some amazing doctors and I think that’s where my interest started. Biology was always my favourite subject in school and I used to say “I don’t want a 9 to 5 desk job” kind of regret saying that now when we have continuous 48 hour duties over the weekend haha. I’m the first doctor in my family and I didn’t have much idea of what I was getting into, there are times when it gets overwhelming and I ask myself “Why did I even think being a doctor was a good idea?” so I come here to remind myself how much I actually love this branch and there are others who feel the same. There’s also my favourite 2000’s medical show called [Scrubs] that I keep rewatching and that’s where my username comes from :)
I’m only done with one degree and there’s a lot more to study. I was lucky to find a mentor who motivated me to read more and teachers who make the subjects interesting but I do get distracted a lot while studying on my own. I can understand how hard it must be for you. I researched a bit on studying techniques over the past few years and found some ways that work for me-
1. I use this famous focus app called Forest to stop me from checking my phone while I’m studying for long hours at a time. I usually set it to 90-120 min sessions and take small breaks after I’m done (most people prefer the Pomodoro method of 25 mins focus then 5 mins break and repeat, but this works out better for me) I blacklist all the apps that I easily get distracted with and only check them after a session has ended.
2. If I’m about to read up on a certain topic, I first try to find a video on that topic, it helps me get an overview and understand the topic better when I read it. I respect teachers who don’t mind sharing their knowledge for free on YouTube!
3. I take a lot of notes while studying from my textbooks, mostly just scribbling on a single piece of paper, simplified diagrams and flowcharts so that my brain doesn’t go on auto-pilot mode (where I don’t even remember what I just read) it helps me actually understand what I’m reading.
4. I make a lot of flashcards- both digital and pen and paper ones, it helps me retain the information better. The app I use for this is called Feyn and I keep revising them after a certain time (Spaced-repetition). I also solve a lot of questions (multiple choice ones) which helps me retain what I learned rather than just passively reading the topic.
You can read more about Active Recall here.
5. Good (Japanese) stationary that makes studying fun :) I love colour coding my notes for eg. green for drug names and pink for microorganisms, red for information that is often tested. I also make a checklist of reading goals for the day.
6. My Mom suggested that I should have a dedicated space in my room that is only used for studying. This helped me concentrate better. I used to study on my bed when I was younger but I often fell asleep.
7. This may sound a bit cheesy but I’ve written my goals on a post-it on my wall as a reminder but my mentor says “Motivation fades over time, consistency is the key” so I try to read everyday even if it’s just for 30mins to 1 hour to make it a habit.
Hope this helps!
30 notes · View notes
spicymarg69 · 1 year
Text
4 notes · View notes
fivehundredwords · 1 year
Text
Alzheimer's Disease: biomarkers and neuroimaging markers cheatsheet for research articles
As Alzheimer's Disease (AD) research skews toward understanding the brain than the pathogenic proteins, studies exploring biomarkers and neuroimaging are hopeful toward developing a method for successful prevention of AD. A biomarker is a molecule, whose presence indicates abnormality or disease, and thus, is crucial in diagnostic procedures. Levels of certain molecules is notably altered in cerebrospinal fluid and in blood plasma, which helps in diagnosing the occurrence of AD. Neuroimaging involves the use of techniques such as magnetic resonance imaging and computed tomography to observe neuronal activity in the brain. This is good news, especially for AD, as the asymptomatic stage of the disease can be identified early enough.
Although the exact function and involvement in clinical practice is not profuse, altered concentrations of these biomarkers in plasma or cerebrospinal fluid encourage further research:
Amyloid and tau serve as the unsurprising biomarkers of AD pathology.
Neurofilament-light chain (NF-L) and visinin-like protein-1 (VILIP-1) are the most promising biomarkers of neuronal injury.
Post-synaptic protein neurogranin (Ng) and pre-synaptic proteins synaptosome-associated protein-25 (SNAP-25) and synaptotagmin-1 (Syt-1) are considered major biomarkers of synaptic injury.
Brain and CSF levels of tumor necrosis factor alpha (TNF-α) and increased levels of interleukin group of proteins (ILs) indicate intensified microglial response to neuroinflammation.
TREM2 receptor and YKL-40 glycoprotein are also reliable indicators of inflammation and impaired clearance of amyloid beta.
Heart-type fatty acid-binding protein (hFABP) could be a marker for pathology in blood vessels supplying the brain. Some vascular markers also show potential as markers of vascular injury in AD: von Willebrand factor (vWF) and monokine induced by γ-interferon (MIG, also known as CXCL-9).
Concentrations of TAR-DNA binding protein (TDP-43) in the brain and plasma and serum indicate, even contribute to, inflammation, mitochondrial dysfunction, and neuronal/synaptic injury in AD.
Neuroimaging techniques reveal structural, functional, and diffusion-related activities of the neurons. To identify them, markers are tracked in images obtained. Each marker is determined with the activity and biochemistry of the group of/individual neurons being studied.
Structural MRI will show location and severity of atrophy which can be identified in grey scale images by applying programs that create analogous color grading.
Functional MRI relies on blood oxygenation level dependent (BOLD) signal which reflects changes in blood oxygenation levels in response to neural activity.
Diffusion weighted imaging (DWI) focuses on diffusion of water molecules. A tensor model is applied to images obtained from DWI. The diffusion tensor imaging (DTI) metrics thus obtained help in studying connectivity through structural integrity of white matter tracts.
Tractography involves 3-D reconstruction of white matter as observed in DWI, which provides a more detailed look into a patient’s neural networks.
In positron emission tomography (PET), markers are identified and labelled so their features or functions can be traced during this procedure to obtain a resulting PET scan. The imaging procedure is named according to its marker: amyloid-PET, tau-PET, FDG-PET, inflammation-PET, receptor-PET.
FDA approved drugs Galantamine, Rivastigmine, and Donepezil alleviate symptoms such as memory loss and confusion in mild to moderate AD, although their effects seem to be negligible. They also cause nausea and vomiting as side effects and are not suitable for every patient. Recently approved drugs, Aducanumab and Lecanemab focus on removing accumulated amyloid. Their effectiveness is still doubted on the basis of studies finding that targeting amyloid has little to do with curbing the actual progression of the disease.
bibliography -
Tarawneh R. Biomarkers: our path towards a cure for Alzheimer disease. Biomarker insights. 2020 Nov;15:1177271920976367.
Cavedo E, Lista S, Khachaturian Z, Aisen P, Amouyel P, Herholz K, Jack Jr CR, Sperling R, Cummings J, Blennow K, O’Bryant S. The road ahead to cure Alzheimer’s disease: development of biological markers and neuroimaging methods for prevention trials across all stages and target populations. The journal of prevention of Alzheimer's disease. 2014 Dec;1(3):181.
Medications for Alzheimer's Disease Stanford Healthcare. Accessed 21-04-2023.
6 notes · View notes
voicebookonline · 2 years
Text
Tumblr media Tumblr media Tumblr media Tumblr media Tumblr media Tumblr media Tumblr media Tumblr media Tumblr media Tumblr media Tumblr media Tumblr media Tumblr media Tumblr media Tumblr media Tumblr media Tumblr media Tumblr media Tumblr media Tumblr media Tumblr media Tumblr media Tumblr media Tumblr media Tumblr media Tumblr media Tumblr media Tumblr media Tumblr media Tumblr media
The Best Books in Clinical Medicine Basic Sciences
4 notes · View notes
creativitytoexplore · 2 years
Text
Diabetes Drug Linked to Lower Risk of Dementia, Study Finds
Diabetes Drug Linked to Lower Risk of Dementia, Study Finds
Photo: Shutterstock (Shutterstock) New research this week is the latest to suggest that some drugs meant to treat type 2 diabetes might also help prevent dementia in high-risk groups. The study found that older people who used a relatively older class of antidiabetic medication were less likely to develop dementia than those who used other common antidiabetic drugs. The findings might warrant…
View On WordPress
2 notes · View notes
Text
Eli Lilly's Tirzepatide Weight-Loss Drug Effective in New Trial
Eli Lilly’s Tirzepatide Weight-Loss Drug Effective in New Trial
Photo: Darron Cummings (PA) Pharmaceutical company Eli Lilly last week disclosed the latest data from a phase III trial of its experimental type 2 diabetes and obesity drug, tirzepatide: People who took the drug lost up to 22% of their body weight and achieved far greater weight loss on average than the placebo group. The findings, while preliminary, suggest tirzepatide may become the second…
Tumblr media
View On WordPress
3 notes · View notes
drnic1 · 6 months
Text
The Good, The Hype, and The Doctor's Perspective
AI in Healthcare This week I am talking to Rob Brisk, MBChb PhD Chief Scientific Officer for Eolas Medical (@EolasMedical). Rob has a fascinating background with experience in both healthcare and machine learning and artificial intelligence. Robe shares his journey from being a physician to venturing into the world of AI and emphasizes the importance of clinicians’ involvement in AI…
Tumblr media
View On WordPress
0 notes
journalofclinical · 6 months
Text
Comparative Study of Enzyme Linked Immunosorbent Assay (ElISA) and Rapid Test Screening Methods on HIV, HBsAg, HCV and Syphilis among Voluntary Donors in Owerri, Nigeria
Tumblr media
A comparative study of Enzyme linked immunosorbent assay (ELISA) and rapid test screening method on HIV, HBV, HCV and syphilis among voluntary donors was investigated on 350 subjects in Owerri. They were 250 males and 100 females, all ranging from the age of 21-50 years. Transfusion transmissible infections (TTIS) are the major problem associated with blood transfusion. Accurate estimates of risk of TIIS are essential for monitoring the safety of blood supply and evaluating the efficacy of currently employed screening procedures for immunodeficiency virus (HIV 1 and 2) hepatitis B virus (HBV), hepatitis C virus (HVC) and syphilis using both enzyme linked immunosorbent assay (ELISA) and rapid test screening method.
Read more about this article: https://lupinepublishers.com/clinical-community-medicine/fulltext/comparative-study-of-enzyme-linked-immunosorbent-assay-elisa-and-rapid-test-screening-methods-on-hiv.ID.000137.php
Read more Lupine Publishers Google Scholar articles: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=vfbCW-wAAAAJ&citation_for_view=vfbCW-wAAAAJ:kh2fBNsKQNwC
0 notes
Text
Medicine Journal of Case Reports: Imaging in Medicine
Tumblr media
Medicine Journal of Case Reports: Imaging in Medicine accepting journal of Medicine, case reports in Medicine, case reports journal in Medicine, journal of Medicine case reports, journals publishing Medicine case reports, journals accepting Medicine case reports, where to submit or publish Medicine case reports, imaging journal in Medicine etc. Medicine Journal of Case Reports: Imaging in Medicine is a continually updated, evidence based review journal covering internal medicine and its subspecialties. Medicine Journal of Case Reports: Imaging in Medicine is an authoritative and comprehensive resource that provides all clinicians, irrespective of specialty, with ready access to up-to-date information on mechanisms of disease, diagnosis and management so that patient care may be optimized.
Journal Homepage: https://www.literaturepublishers.org/
Medicine Journal of Case Reports: Imaging in Medicine is a peer-reviewed journal established for ensuring the rights and benefits of Medicine specialists. Medicine Journal of Case Reports: Imaging in Medicine is devoted to the promotion of health sciences and related disciplines.
Manuscript Submission
Authors may submit their manuscripts through the journal's online submission portal: https://www.literaturepublishers.org/submit.html
(or) Send an e-mail attachment to the Editorial Office E-mail Id: [email protected]
0 notes
actu-real · 1 year
Text
The Benefits of Participating in Clinical Trials
Tumblr media
Clinical trials play a crucial role in advancing medical research and finding new treatments for various health conditions. While participation in clinical trials is voluntary, it can bring many benefits to the participants. By participating in clinical trials, participants get access to new treatments that are not yet available to the general public. They get the opportunity to receive cutting-edge treatment from leading experts in the field. The treatments offered in clinical trials are often more advanced than the standard treatments available, and participants can benefit from them.
0 notes
tmedic · 2 years
Text
Tumblr media Tumblr media
Visited London Science Museum !! ❤️🤩My heart&brain is still at Medicine section … 💯😍
48 notes · View notes
amiralibanani · 1 year
Text
My Internship at the Centre for Cardiovascular Innovation — Centre d’Innovation Cardiovasculaire (CCI-CIC)
April 8, 2023
Tumblr media
Tumblr media
From March 21–24, 2023, I had the splendid opportunity to intern for a short period at the Centre for Cardiovascular Innovation, a clinical research centre operated by the University of British Columbia (UBC) Faculty of Medicine that facilitates regional and international clinical trials for cardiovascular researchers in BC investigating novel therapies for the treatment of certain cardiac conditions. This internship took place at Diamond Health Care Centre and Jim Pattison Pavilion at Vancouver General Hospital in Vancouver, Canada under the guidance of Dr. Brady Robinson. Below are some of the incredible activities that I did at CCI-CIC as well as my reflections on the experience.
Activities
Overview of CCI and the innovative projects that CCI researchers are working on to revolutionize cardiac procedures. This was led by Dr. Brady Robinson, Clinical Research Project Manager at CCI-CIC, whose current research project — called COMPLETE TAVR (CTAVR) — focuses on essentially combining Transcatheter Aortic Valve Replacement (TAVR) and Percutaneous Coronary Intervention (PCI) into a single procedure that can help patients with symptomatic aortic stenosis (AS) get treated while managing their concomitant coronary artery disease (CAD). Currently, patients who have CAD and have had PCI done in the past can not receive a TAVR to treat their AS, but CTAVR is set to make it possible to do so. The study is a stratified randomized trial led by the UBC Faculty of Medicine / Vancouver General Hospital with participating medical research institutions across Canada and the United States. 4,000 patients and 100 participating institutions are required for the study (∼200 patients and 60 institutions have been incorporated as of March 2023), and once complete, CTAVR would be the largest study of its kind in the world. Its results will be published in the prestigious New England Journal of Medicine and could have tremendous implications if successful.
Observing cardiac catheterization procedures in the Cardiac Catheterization Laboratory (Cath Lab) at Vancouver General Hospital. In these procedures, catheters were inserted through the patients’ common femoral artery and pushed up to the heart to assess blood flow in the coronary arteries with angiography (using X-Rays and contrast dye injected by the catheter). The catheters were also used for PCI: a coronary revascularization procedure performed by the insertion of stents that open up blocked coronary arteries in patients with CAD.
Assessing the suitability of several patients to participate in the CTAVR research study using inclusion and exclusion criteria assessing the patients’ current cardiac health (based on measures such as heart rhythm, blood pressure, jet velocity, LVEF, AVA area and index, lesions in coronary arteries, and NYHA Functional Classification during physical activity) and medical history (which entails past cardiac or other related medical conditions and operations).
Reflections
For me, the most influential part of my work experience at the UBC Centre for Cardiovascular Innovation was acquiring first-hand insight into COMPLETE TAVR, the flagship research project that the team of CCI researchers is working on. Once again, this developing research study is aiming to develop a method to treat a condition known as aortic stenosis in patients with coronary artery disease using cardiac catheterization, which dismisses the need for surgical procedures. As part of this experience, I got to observe the day-to-day tasks of Dr. Brady Robinson (as a reminder, the Clinical Research Project Manager of CTAVR), who regularly hosted meetings with scientists from different health institutions across Canada and the United States who are participating in the study and sought to recruit new patients for the study based on a set of inclusion/exclusion criteria to determine whether they are suitable to participate in CTAVR. As previously explained, as part of one of my favourite activities, I played the role of a research coordinator as I got to review these criteria and decide whether a set of four patients with different cardiac conditions and medical histories were eligible for the study. And of course, I had the opportunity to observe live cardiac catheterization procedures in the Cath Lab at Vancouver General Hospital, which was a tremendous experience!
During my time at CCI, I learned a lot about how new research studies are formulated and developed through an extensive process of research design development, patient and researcher recruitment, and innovation — one that may take several years to prepare and perform. I also learned how and for what purposes cardiac catheterizations are performed to diagnose and treat cardiovascular conditions like coronary artery disease, as well as how modifications to this cardiac procedure can open up a whole new scope of opportunities to treat cardiovascular diseases without the need for risky surgical operations. After completing this work experience, I have developed an even greater understanding and passion for medical research.
The biggest challenge I had during my placement was probably in the Cath Lab at VGH as I tried to understand step by step what was going on during the cardiac catheterization procedures through the monitors in the control room that displayed the angiographic images and ECG recordings. The angiographic images were black and white and — before the dye was injected by the catheter to highlight the coronary arteries — showed the heart, its arteries and the surrounding parts as faded objects, which sometimes made it difficult to identify where the catheter was during the process and thus what exactly was happening at each stage of the catheterization. The way I overcame this challenge was by simply asking the specialists in the control room to explain to me exactly what I was looking at on the angiogram as well as what was going on at each step, whether it was the insertion of the catheter through the aortic arch and into the heart or the injection of iodine dye into the coronary arteries (a more visually prominent step). Always satisfy your curiosity by asking questions, which in turn will satisfy your thirst for knowledge!
Conclusion & Appreciation
My goals for this placement were to deeply explore some of the innovative research taking place at CCI and acquire experiential exposure to the process of research in medicine, which I would love to pursue in the future. I have certainly achieved these goals as I am now much more aware of the large-scale preparation that goes into making studies like COMPLETE TAVR possible.
I sincerely thank Dr. Brady Robinson for spending time off his busy schedule to show me around and teach me about CCI as well as the COMPLETE TAVR project and Dr. Jacqueline Saw for demonstrating first-hand how cardiac catheterizations work in the Cath Lab at VGH. This work experience certainly wouldn’t be so rewarding without them.
I laud the efforts being made by researchers at CCI-CIC to innovate in the field of Clinical Cardiology and wish them the greatest success in the future.
CCI-CIC website: https://cci-cic.org
0 notes
fivehundredwords · 7 months
Text
September 21 - World Alzheimer’s Day
On this day, Alzheimer’s Disease International organizes events to raise awareness of the latest developments on Alzheimer's research, treatments, clinical trials, etc. conducted all across the globe.
On top of that, every year they release an almost 500-page report with papers on clinical, social, emotional, and financial consequences on people with Alzheimer's Disease, their caretakers and loved ones, and healthcare systems and policies.
They've also made multiple articles about diverse topics that highlight the timeline of Alzheimer's research and awareness progression in the world. This includes major drug trials, statement on donepezil and anti-dementia medications, their work with policymakers, etc.
This information is available for each year. Their webinar, "COVID-19 vaccines: The global dementia movement and how you can help" describes the journey of the vaccine from WHO's Dr. Shalini Desai. It further gives a unique insight into the lives of those with dementia and how their lives were affected by the pandemic.
Indulge in reliable dementia research to your heart's content at the link below. Bye :)
Tumblr media
0 notes
lycheebugzz · 1 year
Photo
Tumblr media
mr netter has blessed me yet again with more art references
1 note · View note