Suffering from a bout of insomnia this morning and found myself reading about the genetics of longevity. I'd never thought about it in such terms, but the accepted logic among the non-woo crowd seems to be that deleterious mutations which manifest early in life are genetically unfit, while mutations that don't negatively affect you till later in life can slip under the radar. If you've got a 1/20 chance of being eaten by a grue in any given year, something that doesn't kill you till you're 50 isn't as dangerous as grues. If a mutation gives you an advantage evading grues (or finding food, or getting people to fuck you, or whatever) in the early years and only have bad side effects later in life, then that's also genetically fit. Combine these effects and you get a natural lifespan for an organism. For humans this is less than 10^2 years even though the lineage of all our cells runs back more than 10^9 years. And we're a fairly long-lived species!
This is just...awful. It's senseless and stupid and unnecessary. An intelligently designed genome would eliminate or mitigate as many deleterious mutations as possible, but natural selection is a blind idiot god that isn't optimizing for any value besides maximizing the number of copies of each gene. For multicellular organisms, this has generally (though not universally) resulted in a ticking time-bomb locked into the very code that makes us us.
This was even more depressing to read about in context, because this book is about animal intelligence (specifically, cephalopods), and humans are probably the longest-lived quasi-intelligent species on the planet. Octopuses and cuttlefish are so full of ingenuity and personality and usually die after just a year or two. Imagine how much more they could think and do if they lived as long as humans do—and now imagine how much more we could do with the same factor of life extension.
We're lucky, though, in that we might be able to do something about it eventually. Death is, speaking pretty much literally, a genetic disease. And applied intelligence is the cure.
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The story here is truly wild and highlights the power games have in terms of bringing people together. It’s something I have a lot of personal experience with as well.
And then there’s the top comment, which says:
Yoshi-P's blog post about him is so touching. Especially this last paragraph..... "Once time passes, I'm sure there will be a day when I can see him again. When that happens, I'm sure he'll find me with a sprout on my head, not knowing my right from my left, and reach his hand out to me with allies he found on the other side, saying: "Oh, you must be a newcomer! It's okay, it's lots of fun over on this side, too. Let's go adventuring together!" And in that hand, will be the Nu Gundam."
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Headcanon that when Jason so much as says “ow..” on the comms the rest of the batfam immediately assume he must be dying.
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are you kidding me his bald ass is busted in a day
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David Szymanski: in my game i have invented the Iron Lung as a cautionary tale
Billionaires: at long last, we have created the Iron Lung from classic horror game Don’t Create The Iron Lung
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omg its death!!! hi!!!!! hiiiiiiii
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Our immortal descendants will look back on this period with incomprehending horror at how we managed to be so blasé about the current state of affairs.
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