Sharing Brains

Brain imaging resource of data collected from individuals genetically inheriting predisposition to Alzheimer's disease provides insight into the onset in the much larger population who develop the disease sporadically and into brain ageing generally

Read the published research paper here

Image from work by Nicole S. McKay and colleagues

The Dominantly Inherited Alzheimer Network, Washington University in St. Louis, St. Louis, MO, USA

Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)

Published in Nature Neuroscience, July 2023

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Alpha waves (8-12 Hz) are accompanied by a sense of peace and calm.

"The Body Keeps the Score: Mind, brain and body in the transformation of trauma" - Bessel van der Kolk

Brain 

July 2022: In which I get my brain scanned!

My newsletter for July 2022: In which I get my brain scanned!

This month’s Lingthusiasm episodes were a special double feature from my trip to Boston to get my brain scanned and finally discover whether I am one of the extremely special left-handed people who has their language centres on the right or both sides of the brain instead of the left. Spoiler: I am not, mine is on the right, just like most other people, left- and right-handed. However! It was…

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I think they should let you keep a mini picture of your brain when you get a brain scan like they do with school photos?

Give it to me on a keychain, or a mug, I just want a picture of my silly little brain doing it's silly little things

I'm getting a brain MRI... oh no... they're gonna find out I have no brain but am piloted robotically by a bunch of fiddler crabs

A cognitive disorder does not directly lead to aberrant behavior, but the propensity is there. Many criminals are psychopaths, but not all psychopaths are criminals. But the traits can manifest themselves in other ways that may negatively impact interpersonal relationships.

Brain 🧠 Scan Rug by RareRug.

Risk Regions

In the brains of Alzheimer’s disease patients, protein clumps accumulate – in the form of amyloid plaques and tau tangles – leading to neurodegeneration. Certain regions of the brain are more susceptible to this pathology than others, but why? Recent research based on brain scans of hundreds of middle-aged and older volunteers, suggests it’s something to do with regional differences in the activation of a protein called APOE. Indeed, these heat maps show areas of the brain where APOE is especially active (top row, orange and red areas), and where tau tangles are especially abundant (bottom row, orange and red areas) – note the striking overlap. APOE is a fat-handling protein, and a specific version of it – APOE ε4 – is associated with increased risk for Alzheimer’s. While questions about the disease mechanism remain, the finding of this APOE-pathology link provides a piece of the puzzle that will likely inform future research and interventions.

Written by Ruth Williams

Image by Diana Hobbs, Washington University

Research by Aylin Dincer and colleagues, Mallinckrodt Institute of Radiology, Washington University School of Medicine, Saint Louis, MO, USA

Image copyright held by Diana Hobbs

Research published in Science Translational Medicine, November 2022

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This was important new information about how traumatized people process nontraumatic information that has profound implications for understanding day-to-day information processing.

"The Body Keeps the Score: Mind, brain and body in the transformation of trauma" - Bessel van der Kolk

Reading minds by combining generative AI and brain scans A decade ago, UC Berkeley researchers decoded fMRI data of people's brains to reconstruct images of movie trailers they had previously watched. Back then, the images were noisy and grainy. If you didn't know what you were looking at, it wasn't easy to make sense of them. — Read the rest https://boingboing.net/2023/03/03/using-generative-ai-and-brain-scans-to-read-minds.html

We know now that there is another possible response to threat, which our scans aren't yet capable of measuring.

"The Body Keeps the Score: Mind, brain and body in the transformation of trauma" - Bessel van der Kolk

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