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eosinophil-hate-blog · 11 months

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#pharmacology #medication #medical meme #mechanism of action #medications

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lupinepublishers · 2 years

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Lupine Publishers | Palauamine and Olympiadane Nano Molecules Incorporation into the Nano Polymeric Matrix (NPM) by Immersion of the Nano Polymeric Modified Electrode (NPME) as Molecular Enzymes and Drug Targets for Human Cancer Cells, Tissues and Tumors Treatment under Synchrotron and Synchrocyclotron Radiations

Editorial

In the current editorial, we study Palau’amine and Olympiadane Nano molecules (Figures 1 & 2) incorporation into the Nano Polymeric Matrix (NPM) by immersion of the Nano Polymeric Modified Electrode (NPME) as molecular enzymes and drug targets for human cancer cells, tissues and tumors treatment under synchrotron and synchrocyclotron radiations. In this regard, the development of Chemical Modified Electrodes (CEMs) is at present an area of great interest. CEMs can be divided broadly into two main categories; namely, surface modified and bulk modified electrodes. Methods of surface modification include adsorption, covalent bonding, attachment of polymer Nano films, etc. Polymer Nano film coated electrodes can be differentiated from other modification methods such as adsorption and covalent bonding in that they usually involve multilayer as opposed to monolayer frequently encountered for the latter methods. The thicker Nano films imply more active sites which lead to larger analytical signals. This advantage coupled with other, their versatility and wide applicability, makes polymer Nano film modified electrodes particularly suitable for analytical applications [1–27].

Electrochemical polymerization offers the advantage of reproducible deposition in terms of Nano film thickness and loading, making the immobilization procedure of a metal–based electro catalyst very simple and reliable for Palau’ amine and Olympiadane Nano molecules–encapsulating Carbon nanotubes incorporation into the Nano Polymeric Matrix (NPM) by immersion of the Nano Polymeric Modified Electrode (NPME) as molecular enzymes and drug targets for human cancer cells, tissues and tumors treatment under synchrotron and synchrocyclotron radiations. Also, it must be notice that the nature of working electrode substrate in electro preparation of polymeric Nano film is very important, because properties of polymeric Nano films depend on the working electrode anti–cancer Nano materials. The ease and fast preparation and of obtaining a new reproducible surface, the low residual current, porous surface and low cost of Multi–Walled Carbon Nanotubes (MWCNTs) paste are some advantages of Carbon Paste Electrode (CPE) over all other solid electrodes [28–92].

On the other hand, it has been shown that, macrocyclic complexes of Palau’amine and Olympiadane Nano molecules– encapsulating Carbon nanotubes are interest as modifying agents because in basic media Palau’amine and Olympiadane Nano molecules–encapsulating Carbon nanotubes redox centers show high catalytic activity towards the oxidation of small organic anti-cancer Nano compounds. The high–valence species of Palau’amine and Olympiadane Nano molecules–encapsulating Carbon nanotubes seem to act as strong oxidizing agents for low-electroactivity organic substrates. 1,2–Dioxetane (1,2– Dioxacyclobutane), 1,3–Dioxetane (1,3– Dioxacyclobutane), DMDM Hydantoin and Sulphobe as the anti–cancer organic intermediate products of methanol oxidation as well as formic acid, is important to investigate its electrochemical oxidation behavior in Palau’ amine and Olympiadane Nano molecules-encapsulating Carbon nanotubes incorporation into the Nano Polymeric Matrix (NPM) by immersion of the Nano Polymeric Modified Electrode (NPME) as molecular enzymes and drug targets for human cancer cells, tissues and tumors treatment under synchrotron and synchrocyclotron radiations [93–110].

In this editorial, we decided to combine the above mentioned advantageous features for the aim of Palau’ amine and Olympiadane Nano molecules–encapsulating Carbon nanotubes incorporation into the Nano Polymeric Matrix (NPM) by immersion of the Nano Polymeric Modified Electrode (NPME) as molecular enzymes and drug targets for human cancer cells, tissues and tumors treatment under synchrotron and synchrocyclotron radiations. Furthermore, in this editorial, we prepared poly Nano films by electropolymerization at the surface of Multi-Walled Carbon Nanotubes (MWCNTs) paste electrode. Then, Palau’amine and Olympiadane Nano molecules–encapsulating Carbon nanotubes were incorporated into the Nano Polymeric Matrix (NPM) by immersion of the Nano Polymeric Modified Electrode (NPME) in a solution. The modifier layer of Palau’amine and Olympiadane Nano molecules–encapsulating Carbon nanotubes at the electrode surface acts as a Nano catalyst for the treatment of human cancer cells, tissues and tumors under synchrotron and synchrocyclotron radiations. Suitability of this Palau’amine and Olympiadane Nano molecules–encapsulating Carbon nanotubes–modified polymeric Multi–Walled Carbon Nano tubes (MWCNTs) paste electrode toward the electrocatalytic treatment of human cancer cells, tissues and tumors under synchrotron and synchrocyclotron radiations in alkaline medium at ambient temperature was investigated [111– 153].

For more information about Archive of Organic and Inorganic Chemical Sciences please click https://lupinepublishers.com/chemistry-journal/

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#lupine #lupine publishers #archive of organic and inorganic chemical sciences #organic compounds #biomolecules #polymer chemistry #cluster compounds #chemical biology #mechanism of action #xenobiotic metabolism #lupine publishers llc #open access journals

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beif0ngs · 2 months

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There is no live action adaptations of Avatar: The Last Airbender...

#atla #Avatar the Last Airbender #atlaedit #animationedit #*mine #flashing tw #this is my coping mechanism #praying season 2 of the live action series doesn't get greenlit on Netflix #because if they ruin Toph's characterization i will literally start throwing rocks at people

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medicalshare · 10 months

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Ne figure paraqitet mekanizmi i veprimit te barnave qe mjekojne migrenen. Migrena eshte nje crregullim neurovaskular qe karakterizohet nga dhimbje koke me intensitet te moderuar deri ne te forte me lokalizim unilateral qe perkeqesohet nga aktiviteti fizik. Simptoma te tjera perfshijne nauze te vjella dhe ndjemerine ndaj drites deh zhurmave (fotofobi dhe phonofobi).

Barnat qe bllokjne receptorin e CGRP ne ne qelizat endoteliale te arteries meningeale media. Ketu perfshihen antikorpet monoklonale si erenumab dhe barna te quajtura gepante si alogepant, rimegepant, ubrogepant.

Bllokimi i molekules CGRP me antikorpe monoklonale si eptinezumab.

stimulimi i receptorit 5 HT1B/1D ku perfshihet triptanet si sumatriptan, zolmitriptan.

stimulimi i receptorit 5 HT1F me ditanet si Lasmiditan.

#migraine #neurology #mechanism of action

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makeupreviewandbeautyblog · 10 months

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What Is A Ketoconazole Lotion Used For?

Ketoconazole lotion is a versatile topical medication that has gained significant recognition for its various uses and benefits in dermatology. Derived from the class of medications called azole antifungals, ketoconazole lotion offers a wide range of applications in treating and managing various skin conditions. Ketoconazole lotion has become a go-to solution for individuals seeking effective and…

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#antifungal medication #application guidelines #fungal infections #ketoconazole lotion #mechanism of action #nail infections #scalp infections #skin infections

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frogteethblogteeth · 1 year

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Frog automaton, Switzerland, c. 1820 !

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mobius-m-mobius · 6 months

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#a man who DESERVES A SLICE OF PIE

#mobius #owen wilson #mcuedit #lokiedit #marveledit #loki #loki spoilers #owenwilsonedit #dianagifs #for y'alls sake some ep4 moments instead of a hundred gifs of him being silly and kind over the course of the series but #please stop writing characters to exist solely for conflict when they don't have a leg to stand on ;;;;;#so it's fine to get a jump on refilling the straw machine while the timelines are in constant danger but pie during a break crosses a line #okay sure tell me more 💀💀#of COURSE he has coping mechanisms when the comfort and kindness he naturally extends is rarely returned #free will for all utilized as someone else says?? idc i wouldn't look myself up either and he shouldn't be pressured to #she's only even able to yell at him bc some of the first things he's done since pushing past brainwashing have been saving her life 🙃#ANYWAY peace and love on earth when the dilf of all time is a sweetheart who takes responsibility for his actions 🥰💖#marvel #loki s2 spoilers

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neurotypical-sonic · 9 months

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love it when in shows or movies (I cant remember about the second live action, but at least in ova) tails copies sonics actions but a beat or two behind.... wrow just like the classic games

#idk i just find the look up and crouch actions really cute #love it when they incorporate game mechanics into shows and comics and movies. mwah #egg.txt

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mechanicalinfection · 23 days

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MY GOODBYE.

w/o text under the cut (+ au lore?)

They're both hurt by each other's actions, they're both suffering and dealing with their grief in their own way. Clara lashes out in response to being hurt, meanwhile Phil just stays silent and keeps to himself, not uttering a single word as he lets himself register what has been done.

They're both good, but also both in the wrong. Just unfortunate events, and unfortunate timing. And to clear and add things up:

Clara has no relation to Phil (Springtrap), they've only known each other for a short period amount of time (which means they aren't married or any of that)

That also doesn't mean they weren't friends during this though, but unfortunate things happen. A lot more than people would want, so their relationship is very rocky and bad, as for now.

Clara and Phil have a potential of getting together, but it isn't guaranteed. Nonetheless they care a lot about each other and act like a sweet old couple, with occasional teasing the other here and there, but it's all in good fun

Both have lost someone during this.

They'll still remain friends later in the story, their relationship isn't tainted forever

Both fought each other during this, the only sign of it happening is Clara's subtle bruises on her face in the panel. Phil can manage himself just fine, however Clara is just human. (?)

#art #fnaf #the mechanic's crafts #springtrap #phil robotics #YEAGH THAT'S MY SPRINGTRAP'S NAME NOW :33c #fnaf au #clara schmidt #thats the laddyyy #this is au lore #however its very dark so i will discuss about this later if i get the chance to #theyre both suffering from each other's actions btw its not just Phil that messed up #even if he looks very menacing and sinister here hah #hes a good guy i swear #he just has very grey and questionable morals #anyways EPIC reference am i righ

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foreverppl · 14 days

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Moodboard for Jinnah Beatty (they/she), lead singer of ethereal goth band Mayday Malady.

@infamous-if

Playlist

#romancing august I think but we’ll see what oriana is saying when the updated demo comes out hehe #some quick facts:#they usually go by their last name #her goal with her style is to be constantly mistaken for a beautiful ghost #lots of long skirts/dresses + layers. gossamer looking fabric etc. only ever wears black or white #on stage she’s also usually wearing a mourning veil bc of course she is #half of her love of music comes from the spectacle of it. like being able to construct a persona and exist in it for a little while #like playing make believe #they make a lot of their own clothes. if they weren’t doing music they’d definitely be doing something in fashion.#she deeply deeply hates being misunderstood or having her words/actions be twisted so she’s like pulling her hair out rn lmao #the band’s songs are pretty high usually so she always secretly finds it funny when fans try to sing along and are off key or something lol #the only tattoo they have is seven’s initials and she doesn’t really plan on getting any others #they’re hesitant abt being a positioned as the leader bc sometimes she has issues with reeling in her emotions #and responding reasonably in the moment.#anyway she can’t relate to the loser mc allegations she’s the coolest mf on the scene tbh #but I am sorta… scared for them.#on account of the horrors that are yet to come #bc truthfully they don’t know any coping mechanisms that aren’t just ‘ignore it until it goes away’ lmao #one of the things she is currently ignoring to the best of their ability is seven #if: infamous #mb #mc: jinnah beatty (infamous)

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k-i-l-l-e-r-b-e-e-6-9 · 2 years

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Chucky on the set of Child's Play, 1988

#chucky #charles lee ray #80's #80s #mechanical #toy #doll #1988 #child's play #classic movies #80's movies #supernatural action horror film #classic horror movies #80s horror movies

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utilitycaster · 1 month

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1. Why do you like or dislike this character? - Percy and/or Keyleth?

I like both of them, so:

I like Percy for the surface reasons of intelligence and witty comebacks and the general Taliesin Jaffe Arrogant Guy Is Confidently Wrong About Many Things reasons, but more specifically I like how incredibly aware he is of social structures and doesn't dismiss them as stupid or fake or meaningless just because he is aware how much artifice is involved. I love how much he validates Vex in this, as someone who's been on the other side of that social divide most of her life and who knows she "shouldn't" care but does, deeply. It would be so easy for him to say "look, titles are stupid and fake, I should know, I have one," but instead he says "no, I see what this means to you, because yes it's all an accident of birth and yes it is kind of stupid and fake, but it's also the reason why you lived rough for your teens and early 20s, and you are not silly for wanting this security." I also think he's a great exploration of guilt and of someone who has a lot of complicated feelings from the gods but does value their counsel; we don't get a lot of characters with that sort of nuance. His scene with the Raven Queen remains a standout for me and for all he can be melodramatic and obnoxious at times, he is also like 25, traumatized, and should be at the club. I think the question he answers (why would someone invent the gun) is an interesting one, and I think the way that his story ends up with the obvious inevitable happening and yet he still finds happiness is unexpected and wonderful to see.

I like Keyleth for a lot of reasons people will probably be annoyed about, which is...she is annoying. Annoying women: may we know them, may we be them, and may we raise them. Anyway, I think her terror of doing the wrong thing at the cost of doing anything sets up a fantastic arc for someone who is expected to become a leader. I admire how she knows she's not the most eloquent and is scared of her responsibilities but does not back down from speaking up when she disagrees with the party. I like how she's perhaps the only example of lifespan angst that is actually portrayed as making a lot of sense, especially since she is also extremely young (probably shouldn't be at the club given the bar crawling results. She should be at ZooLights and have like, one cider.) I think in general her fears are incredibly real and make sense for the character and shape her, and that's not something you see portrayed with this amount of depth very often. I stuck with the VM-era portrayal of Percy but I will say I especially love how Keyleth is portrayed in Campaign 3, because Percy hasn't changed a ton in adulthood, merely mellowed out a little, but Keyleth very much has as she's grown in confidence, as she was only at the beginning of that during the Campaign. I think her relationship with Vax is incredibly good for both of them; her sense of belonging to a place and his ability to support. I do like that she gets angry, especially after so much time being insecure, but I feel much has been made of her anger and I don't have a ton to add there, and also while I like that she is angry and expresses it, there are other characters I gravitate to for that specifically. Also I have incredible respect for her having to take on a much bigger magical burden than expected; I have said this before but my longest-running character was in a campaign where the player playing sorcerer switched to ranger, and the cleric left, leaving me as the only full caster and primary healer (though thankfully we got a baller paladin shortly after). The fact that Keyleth had to, and could, be whatever the party needed mechanically was a godsend. I know VM died a lot but they would have died like 20 times more without her and Scanlan and especially without her.

#answered #essayofthoughts #cr tag #*bad percy fan voice* i don't actually care about his mechanics very much. i mean big damage is fun and i love an action surge #but i have never been able to give a damn about dps

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ineed-to-sleep · 8 months

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I'm watching Berserk and I may or may not have hyped myself up to turn my vampire ocs into dark fantasy characters. mmaybe

#sketch tag #so uh. pepper is kind of a guts basically jdjgkckkc #they're both in an army and they butt heads a lot bc pepper is big and stronk but very impulsive and reckless #but there's no griffith situation or anything like that it's just that vince worries abt her #and he's way more restrained as a fighter and a strategist. maybe a commander or second in command #and just like in vtm he's very paranoid and afraid of change. so he worries abt her and is also unhappy in the army but too scared to leave #so he broods a lot and mopes around and gets on her ass abt her recklessness #and just like in vtm pepper is impulsive and has a lot of pent up frustration and she uses the battlefield to release all of it #sometimes overexerting herself and nearly getting herself killed #she also wants to leave bc she's not sure she believes in what they're fighting for anymore. but then she loses her coping mechanism #things change when they have an argument where he reveals he cares abt her sjfjjfkf YES very cliche I am thriving #and she's dismissive at first but after being alone for a bit his words start sinking in #and when they're on a battlefield again there's a moment where they have to retreat and she's about to absolutely not listen to that #but then she has a change of heart bc she remembers what he said + she cares abt him too so she doesn't want him to be hurt by her actions #neither by him getting worried nor trying to come to her aid and putting his life at risk #so she retreats #and he's very happy abt that he thanks her later for what she did #and then she's like yeah sure I guess I didn't die but also guess what. I'm bored #everything she wanted to release back there she just didn't. so she's still frustrated and especially bc she had to admit defeat #and she's an extremely proud person. she's irritated #and he's like aight. I'm gonna fight you then #and she's like what. and he's like yeah #so he picks up a sword and throws another one to her and there's a *sexual tension play-fight* hell yeah babey #I'm having sm fun w this au can you tell jejfjckckkc #eventually they do desert the army they're in bc things get worse and pepper decides she no longer wants to be a part of it #and in a fight or flight moment she pushes vincent to make a decision and he leaves with her #and like the story is only getting started there bc then there'll be some big misteries in the story they're gonna uncover #which. I haven't figured out what they are yet #but either way akhhdskfha I'm having a lot of fun w this #sleep.txt

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vox-ex · 6 months

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magic + spookycorp

supercorptober 2023

“Time expands, then contracts, all in tune with the stirrings of the heart.” ― Haruki Murakami

Or Lena learns to move through the world by actions at every distance. She fall in love with Kara somewhere along the way.

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When she was little it made sense. The world made sense. And she fit neatly in it.

There was a predictability in it.

In days becoming nights becoming mornings. In peeling pages off the calendar on the wall her mother had hung in the kitchen.

There was a simplicity in it.

In the way it hurt when she tripped over the garden wall and scraped her knee. In how it felt better when her mother kissed the bandage she placed over the cut.

Time and gravity and love all falling into order.

Until the day they don't.

Her mother dies and she doesn't know why.

When she is four she is angry at the water.

She gets older she believe's in God just enough to hate him instead.

One day she learns to hate herself for it instead.

And even when see learns the truth of it, buried somewhere in the science of currents and silt and fluid dynamics — it is easier to keep hating herself.

But it is never really the nature of the universe we are angry at, but ourselves, and the conceptions we try to impose on it.

She tries to remember that.

Tries to ground herself in equations and numbers and theorems that reason with the intention every bit of cause and every bit of effect. The trajectory of planets, the dance of electrons, each with a purpose, a path.

She moves with them.

But less easily.

Less predictably.

Her motion through the world less elegant than the science she covers herself with — buries herself in.

She keeps moving though. Because what else is she to do. The universe pushes her forward with the rest of it.

It is a motion that is mechanical, constant — personal.

She collides with the world and it collides with her, over and over and over.

She tries to make herself bend to meet them, to stretch, to compress so that she can remain whole.

Sometimes the world hits her so hard she can still feel the marks on her skin.

She will learn that it is not always bad to be left changed.

She keeps moving. She keeps moving until moving feels less like she colliding with the world and more like falling through it.

Supergirl pulls her out of the sky.

Supergirl pulls her out of the sky and she doesn't know what to do with that.

She calculates odds and statistics and free body diagrams in her head.

She tries to ignore the feeling in the back of her head and somewhere louder in her chest that utters out quantum equations instead.

Tries to tell herself that this is not action at distance. This is not the movement of particles and quanta. This is one body meeting another — nothing more.

It is something more.

It is something more but action at a distance feels no kinder than action up close.

It is full of chaos and uncertainty.

She tries to fit it neatly into boxes.

Puts Kara neatly into a box too.

And even when the science makes sense, it feels too much like fate, like magic, to believe it.

It takes time to believe it.

It takes time and destruction and time again to be put back together.

The first light of dawn crept through the kitchen window, casting a warm glow over Lena's face as she sat at the table, the cup of tea between her hands keeping them warm against the Autumn air drifting in.

"Morning," Kara murmurs as she enters the kitchen, rubbing sleep from her eyes. The corners of Lena's lips turn up in a small smile at the sight of her

Good morning," she replies, taking a sip of her tea.

Kara stretched her arms above her head, the long figure of her body scattering the light on the floor. She pours herself a cup of tea and settls across from her.

Lena contemplated the predictability of it all – that the sun would rise, that they would find themselves at this table, that they would drink tea together.

It's easier to call it fate or magic.

But it was uncertainty that made it possible. The dance of particles and quanta, and for once she was not just their observer, but the result of their movements.

Lena reached across the table and took Kara's hand in hers. She could feel the warmth of her skin, the steady beating of her heart just beneath.

She gives it a small pull.

Kara leans forward at the motion.

They meet as they always seem to do.

As she always hopes they will.

Kara's lips meet hers, warm and familiar.

Her thumb traces the small scar that sits just behind her ear as her hands wander up to thread themselves in her hair.

She leans into her touch.

Bending, stretching, compressing — is made whole by it.

It feels like colliding.

It feels like falling.

It feels a little bit like magic after all.

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read and follow along on Ao3 too

#supercorp #supergirl #supercorptober #supercoptober2023 #sg prompts #after last prompt I felt like maybe Lena could have a little character study too #sorry that means more science #love and science #paradoxes and poetry #spooky action at a distance #inspired by yet more science #and the quote from Einstein which I'm sure probably frustrates my physicists today which called Quantum Mechanics #a nod to Lena's odd magical character arc in cannon #you all have been so great this whole month #thank you so much!

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xbuster · 5 months

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WRONG! I play Dragon Quest games over and over and over again because I fucking LOVE JRPG combat.

#i didn’t love playing through ffx because i found the actual jrpg mechanics to be pretty shallow #also why i hate ffxiii #and like every post-x ff #i also want to play more dragon quest x than ffxiv BECAUSE dqx has turn-based combat #and not boring mmo combat #action rpgs also tend to be boring #the day mainline dragon quest stops being a turn-based jrpg is the day the genre dies for me

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annaofaza · 9 months

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Why does Vash keep smiling?

I love how Milly and Wolfwood are getting a clearer picture of Vash, particularly with his vulnerability. In both scenes, Vash has been through traumatic events; his home was invaded, and a great deal of the people he loved were killed, then Meryl gets captured, Vash recalls July, and the townsfolk (at least the adults) turn on Vash and drive him out based on his reputation (and his wing saving Meryl from a bullet, a monstrous image that does heroic action, which is a whole other post). We with Meryl, Milly, and Wolfwood have seen the Humanoid Typhoon, the sixty-billion double dollar bounty, the Stampede stripped away to Vash. Vash, who has every reason to cry, storm, and beat his fists on the ground. Vash, who keeps on smiling.

Wolfwood and Milly ask: Why?

They conclude this: The world is ugly, but Vash makes a choice and tries to say, It doesn't have to be.

I also find it interesting—given their characters—that Wolfwood seems to gain a sense of peace, almost soft satisfaction, in his realization, while Milly is distraught and takes a more pessimistic view. Wolfwood sees Vash's smile as a choice, and Milly does, too, but directly as a mask. Milly sees the pain, and Wolfwood, the resilience.

But Vash himself weighs in: he has to, even if he can't remember why. He's not smiling for joy, for hope, for tomorrow; he's living to keep Rem alive and eventually stop Knives.

For Vash, it's not exactly a full and conscious choice. Like most things in his life, it's what he's been forced to bear, and he has to keep going.

#trigunbookclub #trigun maximum #trigun #trigun bookclub #my post #is it autonomy? a coping mechanism? a sense of control and purpose? a leaning post? it's everything #the people who love vash seeing the shattering behind the smile 😭#they both know by now vash is no fool; he's actually very deliberate in his actions #it's silly but i thought of spiderman #no matter how hard life is no matter what it throws spiderman always gets back up #is it because he has to? is it his core? is it a curse he's supposed to bear?

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