👑 Sworn Partners ⚔️
(ID: Kirby series fanart of King Dedede and Meta Knight being cute and in love. Top panel - bust shot of DDD scooping MK up into his arms, smooshing the flustered knight against him in a great big hug as a little flurry of hearts bursts from them. Middle panel - bust shot of DDD holding MK in his arms, gazing down at him with an easy grin as the knight pushes his mask to the top of his head, a fond smile on his face as he gazes back. Bottom panel - bust shot of DDD and MK leaning in together to meet in a kiss, eyes closed and faces flushed, the king holding his knight tighter, the knight gently cupping his king’s cheek. More little hearts hover around them, the biggest just above their heads. In all panels, DDD's crown and MK's armor are - as usual - touched with white highlights and dusted with sparkles. END ID.)
Sketch started some time early 2024, render started 03/18/24, finished 04/15/24.
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okay no actually what is the hardy weinburg expected ratio of labrador colors if we pretend purely random mating and no humans making color choices? i.e., how common should chocolate labs be under Hardy Weinburg?
I found a study (open access, even!) that lists the allele frequencies of Labs in three separate populations (UK show, n=104; US field, n=175; US show, n=92) and also pools them in one pan-Lab sample (n=371) for easy analysis. awesome. (okay so I have to scrape those numbers out of the supplementals, but shh.)
that study puts the ratio of the e allele at 0.60 overall: 0.46 for UK show, 0.61 for US field, and 0.75 (!) for US show). excellent.
okay, and apparently there are three synonymous b alleles that can create liver in labs at TYRP1, but they all act exactly the same. so. uh, that's something. for simplicity, let's calculate the allele frequency for B instead...
obviously not all dogs genotyped at all locations, so the ns and allele frequencies for the TYRP1 locus at B for black are... UK show 0.64 (n = 107), US field 0.49 (n = 177), US show 0.83 (!) (n = 92)... with a total sample of 376 dogs here and a combined allele frequency of 0.61 B alleles. we can translate that to say all the non-black alleles (so the remaining fraction needed to make 100% of all the alleles) shakes out with these numbers for the pan-b allele we really care about:
UK show: 0.36
US field: 0.51
US show: 0.17
overall: 0.39
since the formula for the overall proportion of chocolate dogs would be p(bb) * p(B_) (probability of two copies of b = liver AND probability of at least one copy of E for not-yellow)...
easier to score this as p(b allele)^2 (which is the HW phenotypic relationship) and 1-p(y)^2 for the probability of NOT being yellow...
so that would come out with ratios of chocolate phenotypes such within each subpopulation:
UK show: (0.36^2) * (1-0.46^2) = 10.2% of all labs chocolate
US field: (0.51^2) * (1-0.61^2) = 16.3 % of all labs chocolate
US show: (0.17^2) * (1-0.75^2) = 1.3% of all labs chocolate
overall: (0.39^2) * (1-0.60^2) = 9.7 % of all labs chocolate
now I suspect very much that this is NOT the case because of chocolate lab breeders and of course you can selectively breed for anything forever. but this is probably why in many circles chocolate dogs have a reputation for not being "good" dogs: purpose bred lab communities tend not to have them pop up too much and . and especially this is probably driven by how much you give a shit about "yellow chocolates" bc the US show circuit is apparently AGGRESSIVELY trying to minimize the odds there, given that the US show circuit seems to be going in very heavily on yellows.
fuck this paper is awesome actually, it has some really interesting conclusions about breed ancestry and rare allelic variants that indicate deeper relationships. fuckin love that.
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(Out of nowhere, you are approached by a familiar lightbulb-headed Cog.)
Ah, it's you, cat. Thinking you're oh-so-slick. Muttering and whispering under those raggedy whiskers of yours... Thinking I am unable to hear it all...
Well, you've simply underestimated my fantastic hearing. You probably want to know the reason why I'm here, taking a 'break' from my incredibly important scientific breakthroughs? It's quite simple, really!
(She gets close, and squints her eyes.)
I know what you are.
Farewell, now!
(She then leaves the way she came from.)
(Spam giggles immensely, covering her face... it always seems like she's giggling, isn't she? This lasts... at least thirty seconds. Longer than usual.)
And I know what I am too, Sparky! You broke through something, that's for sure. Really, broke through...
(She looks down, continuing to laugh nervously.)
You know, I find it odd you Havent tried to bulb blast me into the stratosphere by now. I mean knowing how you acted with Frostbite. Is there something peculiar about me that you perhaps can't quite track? Something about me that you... don't know what I am?
I know, I know, I'm talking to nobody again. But you were there when I had a moment today with the one the only Frostbite The Bravecog. You may be remaining. Lurking in the shadows. Knowing about these thoughts that I'm thinking.
(The giggling resumes, lasting far shorter this time.)
Your brother's a piece of fucking barp, by the way
(She braces for impact for a few seconds, wincing while smiling, before comically looking around to realize nobody's there. She sighs.)
Wow, okay maybe toony superhero show logic doesn't apply in this situation. Cool.
WAIT I JUST FUCKING REALIZED WHAT SHE MEANT but like. Dude if she meant that then what's the point I mean the whole ahh sellbot department barping knows unless you're Really low on the ladder. Heheh... maybe she did mean what I thought she meant.
Oh i'm so fucking screwed. What kind of bitch gets filament fever
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Reading through the tags of one of my past fics and giving myself a right chuckle. My favourite is the ‘Philosophical Horror’:
Angst
Existential Angst
Existential Crisis
Existential Horror
Philosophical Horror
Cosmic Horror
Eldritch Luke Skywalker
It was just supposed to be an AU where Luke confronts his fears in the cave
Things just got out of hand okay
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