Irma Vep s01e05

Mira and Zoe 💜

In the dynamic landscape of biology, researchers around the world aim to unlock the secrets held in the genetic code. With the introduction of whole genome sequencing, a new world was opened to science: one where genetic blueprints could be unraveled and studied with ease. Recently, the impact of genome-wide variants on human pathophysiology has become the subject of much investigation. Now, researchers from the University of California, Berkeley, have unveiled a neural network model that promises quick and accurate predictions of the effects of such variants, possessing the potential to change the field of precision medicine.

As whole genome sequencing increases in popularity, much attention has been drawn to the need for a better comprehension of the effects caused by genome-wide variants. If understood, they have the potential to become the basis for new research into precision medicine. Specifically, the ability to predict the damaging effects of a particular variant is important for the diagnosis of rare diseases as well as testing for rare variant burdens.

Language models, made popular by the immense fame of ChatGPT, present a prospective solution to this: trained on large datasets, they are able to predict deleteriousness with great accuracy. Protein language models have been developed that can score missense variants successfully, and these show great promise. However, a similar model hadn’t been developed for DNA so that genome-wide variants can be scored.

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Blatantly Partisan Party Review X (NSW 2023): Public Education Party

Prior reviews of parties related to this entity:

Voluntary Euthanasia Party: federal 2013, VIC 2014, federal 2016, VIC 2018; NSW 2019

Reason Party/Australian Sex Party: federal 2013, VIC 2014, federal 2016, VIC 2018), federal 2019, federal 2022

There has been an interesting and somewhat quixotic evolution here. In 2014, the NSW branch of the Voluntary Euthanasia Party was founded. It became the NSW branch of the Reason Party in 2019, in part because it believed it was too narrow as a single-issue party and wished to ally with a federal party that shared its platform on euthanasia. Then, in 2022, Reason NSW considered winding itself up after state parliament legislated for voluntary assisted dying, and because the party had had a consistent lack of electoral success. Instead, it announced it would merge with the obscure and never-registered Fairer Education Party (so obscure I hadn’t heard of them until the merger), which had been formed in 2021 to promote the interests of government schools.

After this merger, the party changed its name to the Public Education Party. So… now they’re a single-issue party again. Jane Caro, who has been a consistent advocate for public education, led the Reason ticket in NSW at last year’s federal election, so a bunch of us micro-party watchers assumed the name change had something to do with her making a run for state parliament. But she is nowhere to be found on the ballot. There is, though, some continuity with the old Voluntary Euthanasia Party: the registered returning officer of the Public Education Party was the lead candidate for the VEP back at the 2015 NSW state election.

Anyway, you’re absolutely never gonna believe the Public Education Party’s main purpose is to promote government schools and the public education sector. They believe that the sector is underfunded and that governments are routinely reluctant to invest in it properly. The policies about education are, consequently, fairly detailed and seek more equitable funding and other reforms to staffing and resourcing in line with the recommendations of the Gonski Review.

I’m pretty sympathetic to this. I went to public primary schools and a private high school; on reflection, my views are strongly in favour of public education and of funding the system to a much greater extent. To me, many private schools would be best nationalised, and the privileges of elite private schools need to be reined in (and certainly not have their handsome income topped up with public money). Indeed, my views on this are stronger than what the Public Education Party says explicitly, which is simply that public schools should be “the preferred educational setting for young people”.

This party is a single-issue vehicle, unlike the more broadly conceived Reason NSW, and I’ve said many, many times that single-issue parties are conceived too narrowly for the fullness of parliamentary business. The background in Reason NSW means I anticipate this party would generally take a centre-left approach to other policies, but all they say is that they are “advocating for social justice and equity, and fighting for a fairer, more cohesive, and productive society”. This is a motherhood statement that doesn’t tell the prospective voter an awful lot. I cannot give any single-issue party an unqualified endorsement.

Recommendation: Give the Public Education Party a decent preference.

Website: https://www.publiceducationparty.org.au/

tried for literal weeks to draw this thank god i finally made her

Das Wunschnetz ...

(Quelle: Verkehrsentwicklungsplan VEP Starnberg, 2016-2019)

Vor ein paar Tagen gab es "die volle Ladung" zum Anschauen. Deshalb heute noch einmal eine mehr aufgeräumte Version des von den Fachleuten für Starnberg gewünschten Radwegenetzes.

Daran gilt es im Bereich des Radverkehrs (parallel zu den anderen Verkehrsmitteln) in den nächsten Jahren weiter zu arbeiten.

Maggie Cheung on the set of Wong Kar-wai's In the Mood for Love (2000).

Maggie Cheung in Irma Vep (Olivier Assayas, 1996)

Maggie Cheung in Irma Vep (1996) dir. Olivier Assayas

Irma Vep (1996) dir. Olivier Assayas

Maggie Cheung in Irma Vep (1996)

IRMA VEP (2022) E05: Hypnotic Eyes

She was an artist, in her own right. One of the first female directors. A novelist and even a film critic. She fell in love with a bullfighter, shot some of her movies in Spain. She was an adventurer. Irma Vep was only one side of her. — Yes, but I also think everything is in Irma Vep. — That's the way I see it, too.

IRMA VEP (2022) E01: The Severed Head

Hitting them with the catification beam!!

I mean, I don’t like American films.

IRMA VEP (1996) dir. Olivier Assayas

Die Umlegung des Radverkehrs

(Quelle: Verkehrsentwicklungsplan VEP Starnberg, 2016-2019)

So ein schönes buntes Bild - aber was soll es bedeuten?

Es ist ein Vergleich vom IST-Zustand (grün) und einem eher theoretischen "SOLL"-Zustand (violett und orange).

Diese Grafik ist für mich eine schöne Zusammenfassung für die bisherigen und zukünftigen Planungen von neuen oder fahrradfreundlicheren Streckenführungen, sofern dies noch nicht geschehen sein sollte.

Es gibt also für dieses Thema mit dem Fahrradverkehrskonzept aus dem Jahre 1998 und dem VEP ausreichend Gutachten, um in den nächsten Jahren (oder auch Jahrzehnten) auf ein Ziel hinzuarbeiten.

Wong Kar-Wai's In the mood for love deleted scene.