Nylakerede Ph 4/3 lamper i guld, lyserød, grøn og sort. H.20 Ø.40 cm. Pris 525 kr pr stk. Velkommen til Tingfinder® lørdag og søndag kl.13-15 på Bjerrevej 370, 7130 Juelsminde. #tingfinder #komogkig #ph4 #ph4/3 #phlamper #poulhenningsen #Loftlamper #designlamper #brugtelamper #lampebutik #retroloftlamper #retrolamper #genbrugslamper #lampeide #lampetips #lampeinspiration #madeindenmark #danskdesign #danishdesign #horsens #hedensted #juelsminde #tingfinder®ermitnavnogvaremærke28år (her: Tingfinder) https://www.instagram.com/p/Cg13hsKMlha/?igshid=NGJjMDIxMWI=

Why is the new Galactic Seasons companion right outside my bedroom? The things she's going to hear.

So anyway. No Solangelo March went great.

Did some more Nathema leveling for @astrifer-bound and once again, GEMINI decided to be ✨spicy✨ with us.

I would be killing the Skytroopers while Lex kept the boss busy, then I’d turn around to help push her the rest of the way down to get to the next phase. But more often than not, even though she’d be at like 45%, she would call another round of Skytroopers before pushing into the next phase. So we’d have the tubes, the clones, and a wave of Skytroopers to contend with. And none of the clones would stay in their damn seats, so they were just running all over the map (on one round, everything just piled on Hexid? Which, helpful that they were all grouped up, but what did Hexid do that was so threatening?). Also, since we didn’t have a phasewalk on the other side of the bridge to reset the fight, we were depending on me to make the roll across the broken bridge to reset the fight (to avoid sewer sliding and having repair bills). But like. You can’t really count on me for parkour. On one of them, graphically I made it, but I then bounced off, but then somehow managed to Mario jump in midair to make it back onto the other side of the bridge. (I had a lot of times when I bounced off and did not successfully jump back on).

There was also one round where Lex just. got obliterated? Immediately? Like ok, dcds whomphst, I guess, GEMINI wanted that bitch dead.

But then on the round that we went ahead and finished the fight, we handed Vinn his ass before he could call for the little backup droid things, and both stood on top of Zildrog to reflect Final Harvest.

PH4$M is finally born!!!

PH4$M:.....Sup

*places 2 goons here*

PH4$M: Is this where the line starts?

Anti: *waves*

“Ah, hello and welcome! Lemme give you a tour of the-“

“I don’t know where you guys even come from, but I’m happy to have all of you here! Now let’s have some good ol’ fashioned circus fun!”

(also Marx has a little quirk with his “hey hey hey”s where he uses the phrase not just as a silly greeting, but in different situations as well. Just with a tone change. Makes for a good running gag, doesn’t it?)

Once upon a midnoon sunny, while I sat there grumpy and thirsty

Over many a quaint and curious volume of cards galore.

While I pondered, close to snapping, suddenly there came a rapping,

As of someone gently rapping, rapping at my game room door

"Tis some gawker," I muttered, "tapping at my game room door --

Only this and nothing more."

Mistii grimaced as the tapping increased to scratching. "What the blazes is going on out there? Can't a girl play cards in peace?"

PH4-LNX, better known as Fae opened the door to see what was disturbing Mistii's attention. "It appears to be an animal."

"Okay," Mistii replied, "and that's our problem ho--"

Just then there was a sound of something hard striking flesh and suddenly Mistii had a small, scared animal huddling under her chair. She looked up to see some of the local toughs laughing and barging into her private game room.

"Hold it right there, boys." she said as she raised her blaster. "This room is reserved and our table is full." She twitched her blaster in a gesture that said 'get out or be thrown out'.

"Aww, come on, lady, we were just looking for our lost pet." One of them said while the others laughed behind him. "We'll just grab the whelp and be on our way."

"Really. Seems pretty sweet of you to be worried about your pet. What did you say its name was again?"

Confused looks were exchanged between the guys before conflicting answers were given. Fluffy, Dusty, Womp Rat were thrown out at the same time.

"So many names for a beloved pet!" Mistii said, eyes narrowing. "How about I give you a good trade for it, you walk away and I sit down and enjoy the rest of my game. Then I walk out of here with the animal. That's one offer. My second offer packs a little more -- punch," she said raising her blaster and widening her stance.

The men looked around at each other nervously, they had heard of a tiny blue-haired woman defeating a bunch of outlaws a few weeks ago and realized that if this was the same woman, they were better off leaving. "Have a good game, Captain."

Mistii sighed, looked under her table at the skinny animal and said, "What have I gotten myself into, Fae?"

Fae made a sound that sounded amused. "This is an akk dog, variation, painted, I believe. Shall I gather the required materials to feed and care for it?"

"A dog. I've never even had a pet before. What am I going to do with a dog?"

One of the other players piped up, "First it needs a name!"

"Yeah, that makes sense. Well," she said as she glanced around, looking at the colorful cards on the table. "how about Pazaak?"

There was a chorus of agreement from the table and Fae might have murmured something about getting it a collar with a name tag on it.

Why Gemini 16 is one of my favourite characters (spoilers for eternal throne and nathema conspiracy lol):

So Vitiate 'suddenly' cared so much about the Eternal Throne because he saw droids as not sentient, therefore not part of the force, therefore the Fleet is a source of unrivalled power that isn't subject to the Force's whims, therefore he wont be a victim of the force seeking balance. That's generally how it goes, right?

What could Revan, Vitiate, or even the Outlander never do? Escape the will of the Force, no matter how hard they push back against its current.

The Jedi can become one with the Force, and the Sith can use it to break their chains. But they're all still ultimately subject to its whims. Jedi can be whisked back as force ghosts to serve its chosen ones, Sith can remain bound to the mortal world.

The Gemini frequency is the droid equivalent of the Force. Yeah, they can be granted free will, but it can just as easily be taken away. Jut as the force grants its power at such a steep cost. Gemini 16 supposedly broke free of the frequency, but could still hear her sisters, so she was still connected to it in some way.

So she made contact with an actual droid god, and had the frequently permanently destroyed. She wouldn't live to experience that true freedom, but she'd ensured no droid would ever become a slave to it again. She did what Vitiate always wanted to do, and she did it by destroying what Vitiate viewed as true power.

And then they gave us PH4-LNX! whose an independent person with her own passions and ideals and struggles!! even if they seem small to us!!! which just proves my point more!!!!!

Does any of this even make sense? Im so tired rn but I listened to the valkorion theme epic remix and i couldnt help but completely re-evaluate my thoughts on the game once again

Soooo which of my Star Forge toons should get the initial unlock on PH4-LNX?

shang chi is the most underrated + one of the best ph4 characters and y'all are so ready for this conversation

also just LOOK AT HIM HE'S SO CUTEEEE

On Galactic Seasons 3

So far I’ve done a couple of weeklies, unlocked PH4-LNX, and went through the side-quest, so these thoughts may change at the end of the season. However, after doing these and reviewing the rewards track, I am less impressed by this seasons offerings. 

In comparison to GS1 and GS2, I feel that this season was rushed. There are some interesting changes (such as making ‘Fay’ your reputation item giver) but it seems less interested in exploring it’s theme. 

From what I can see, there’s no other G.A.M.E. associated npcs other than Fay. Comparatively GS2 really tried to reintroduce the Shadow Syndicate by giving them a presence in the open world. You had Qi’us Dnar as another visible member of the group who had banter with Fen Zeil. Fay mentions the founder of G.A.M.E., Bami Wah, it might have been nice to interact with that character, and see some of their agents in the open world. 

I also find it odd that the rewards track for the season feature decorations that come from Iokath as opposed to being more on brand with Galactic Gaming. Sabaac tables, interactive dejarik tables, betting terminals, all would have been better ideas for decorations than an Iokath crystal thing or a big claw... Perhaps this has something to do with Fay that we learn later on in her quests but it feels jarring to have them there. It’s not like the game lacks for decorations themed around Iokath...

All in all, I think I will definitely take this season at a far more slow and casual pace. I really only want the outfits and the weapons anyway. 

New season and new companion! 

Ph4/NT0mA

Unleash The Archer veröffentlichen dritte Single

Die kanadischen Modern-Power-Metal-Ikonen UNLEASH THE ARCHERS haben kürzlich die bevorstehende Veröffentlichung ihres gewaltigen sechsten Studioalbums "Phantoma" angekündigt, das am 10. Mai 2024 über Napalm Records erscheint! Nach den ersten beiden Singles "Green & Glass" und "Ghosts In The Mist" hat die fünfköpfige Band aus Vancouver heute ihre dritte Single "Seeking Vengeance" veröffentlicht, zusammen mit einem neuen Musikvideo! Der Song beginnt mit einem rasanten Gitarren-Lead und modernisierten Power-Metal-Attacken, bevor er mit einem kraftvollen Refrain und einem vertrackten Doppelsolo einsteigt. Auf dem neuen Konzeptalbum begleiten die Hörer die Protagonistin Phantoma, eine Phase 4 / Network Tier 0-Einheit - Modell A, auf einer inspirierenden, aber auch erschütternden Reise, auf der sie die brutalen Wahrheiten hinter dem künstlichen Glanz des Social Media-Postings auf einem dystopischen, fast zukünftigen Planeten Erde entdeckt. Mit ihrer einzigartigen Mischung aus Power Metal, traditionellem Heavy Metal, modernem Prog und Pop-Sensibilität spinnt Phantoma ein Netz aus scharfer Musikalität, High-Science-Fiction-Konzept und wichtigen sozialen Kommentaren. Brittney Slayes von UNLEASH THE ARCHERS sagt über "Seeking Vengeance": "Dies ist der Moment in der Geschichte, in dem Phantoma sich darüber klar wird, was sie tun muss und wer sie werden muss, um es zu tun. Wir haben wirklich hart daran gearbeitet, dass die Musik die Energie dieses Moments widerspiegelt, und ich denke, dass auch das Video den inneren Kampf gut wiedergibt. Das Video wurde von den Jungs von RuneGate Studio gefilmt und geschnitten, und sie haben sich auf die Beleuchtung und verschiedene Objektive konzentriert, um ein dynamisches visuelles Erlebnis zu schaffen. Der Song ist der düsterste Moment des Albums, aber er wird von einer erhebenden Refrain-Melodie begleitet, die von klassischen Disney-Heldenhymnen inspiriert wurde. Dieser Song wurde von uns einstimmig als Single ausgewählt und wir können es kaum erwarten, ihn bei unseren kommenden Shows live zu spielen! Hope you enjoy." Durch die Verflechtung von Realität und Fantasie wurden UNLEASH THE ARCHERS dazu inspiriert, bei der Entstehung von Phantoma Elemente der Künstlichen Intelligenz zu verwenden, um dem innovativen Thema gerecht zu werden. Frontfrau und Texterin Brittney Slayes entwickelte das Konzept des Albums im Jahr 2021, also noch bevor der Presserummel um die Künstliche Intelligenz einen neuen Höhepunkt erreichte. Die Band hat elektronische und Synthwave-Elemente in die 10 kolossalen Hymnen des Albums eingewoben, die sich - passend zum Thema - im Vergleich zur hellen Positivität von Abyss als viel düsterer und schwerer erweisen. Der Album-Opener "Human Era" gibt den Ton an mit Bildern einer düsteren, windgepeitschten Zukunftslandschaft, die kopfüber in das halsbrecherische Tempo der Power-Metal-Bastion "Ph4/NT0mA" übergeht - ein Meisterwerk aus duellierenden Gitarrensoli und Gesangsakrobatik. Das Trad-Metal-beeinflusste "Buried In Code" weist mit stampfenden Rhythmen den Weg, bevor das Album mit dem Heavy-Metal-lastigen "The Collective" in die Dunkelheit abbiegt. Brittney Slayes' warme Töne laden den Hörer ein, sich anzuschließen oder zur Seite zu treten! Die haarsträubende erste Single "Green & Glass" enthüllt die Wahrheit, bevor das beschwingte, an die 80er Jahre angelehnte "Gods In Decay" und die außergewöhnliche balladeske Hymne "Give It Up Or Give It All" die vielfältigen Songwriting-Fähigkeiten der modernen Ära von UNLEASH THE ARCHERS unter Beweis stellen. Ein Dreiergespann von Konzept-Songs beginnt mit dem stimmungsvollen "Ghosts In The Mist", das in das lautstarke und bedrohliche "Seeking Vengeance" übergeht, bevor es mit der bittersüßen Geschichte von "Blood Empress" endet. Gemischt und gemastert von Jacob Hansen und mit Lead-Gitarrist Andrew Kingsley am Ruder als Hauptsongwriter und Produzent, ist Phantoma ein aufregender Fortschritt in UNLEASH THE ARCHERS' Songwriting- und Storytelling-Meisterschaft und ein riesiger Sprung nach vorne in ihrer überragenden musikalischen Laufbahn. Phantoma folgt auf das 2020 erschienene Album Abyss, das mit dem JUNO Award für das Metal/Hard Music Album des Jahres ausgezeichnet wurde, nachdem es auf Platz 1 der US Current Hard Music und Top New Artist Charts debütierte und von Bandcamp als "Pflichtmusik" betitelt wurde. Phantoma track listing: 1. Human Era 2. Ph4/NT0mA 3. Buried In Code 4. The Collective 5. Green & Glass 6. Gods In Decay 7. Give It Up Or Give It All 8. Ghosts In The Mist 9. Seeking Vengeance 10. Blood Empress Phantoma wird in den folgenden Formaten erhältlich sein: -Earbook Edition mit 2CD (2 Bonustracks und Instrumentalversion des Albums), 7" Single (2 Bonustracks auf schwarzem Vinyl), 60 Seiten Booklet (nur bei Napalm Mail Order - limitiert auf 1000) -2LP Gatefold in Phantoma Cristallo Multicolored Splatter (nur bei Napalm Mail Order - limitiert auf 300) - NEU! -2LP Gatefold in Marbled Orange Red mit 24-seitigem Vinyl-Booklet und Kunstdruck (nur bei Napalm Mail Order - limitiert auf 300) - AUSVERKAUFT! -2LP Gatefold in Glow In the Dark (nur bei Napalm Mail Order - limitiert auf 300) -2LP Gatefold in Splatter Aquamarin Orange (nur bei Napalm International Mail Order - limitiert auf 300) -2LP Gatefold in Transparent Lime Green (nur Napalm North American Mail Order - limitiert auf 300) -2LP Gatefold in Silber (nur nordamerikanischer Indie-Einzelhandel - limitiert auf 700) -2LP Gatefold in Schwarz Kassetten-Edition in fluoreszierendem Grün mit weißem Aufdruck (nur im Napalm-Versandhandel - limitiert auf 200) CD-Edition im Schmuckschuber -digitales Album UNLEASH THE ARCHERS is: Brittney Slayes - Vocals Scott Buchanan - Drums Grant Truesdell - Guitar, Vocals Andrew Kingsley - Guitar, Vocals Nick Miller - Bass Lesen Sie den ganzen Artikel

VitaImmuno pH4: Intravenous Immunoglobulin Potency

Introduction Human immunoglobulin, also known as intravenous immunoglobulin or IVIG, is a therapeutic preparation of pooled human immunoglobulins obtained from the plasma of healthy donors. It contains a balanced mixture of immunoglobulin G antibodies against various infectious agents. IVIG therapy aims to replace the missing antibodies in patients with primary or secondary immunodeficiencies. This article discusses the composition, mechanism of action, indications and administration of pH4-adjusted IVIG.

Composition IVIG contains mainly immunoglobulin G (IgG) antibodies extracted from donated human plasma by fractionation processes. It consists of over 95% intact IgG molecules with traces of IgA and IgM. The immunoglobulins in IVIG have specific pathogen-directed antibodies against bacteria and viruses that infect humans. The IgG antibodies are polyclonal, which means they contain a wide variety of antibodies that react against various microorganisms. The pH4-adjusted formulation of IVIG has a neutral pH between 4-5 to reduce the risk of acute kidney injury.

Mechanism of Action Human Immunoglobulin (pH4) for Intravenous Injection works through multiple mechanisms to boost the immune system. It replaces the missing antibodies in immunodeficient patients by providing passive immunization against pathogens. The exogenous IgG antibodies bind to Fc receptors on phagocytes, B cells, and other immune cells to facilitate opsonization and elimination of infectious agents. IVIG also modulates the immune system by inhibiting pro-inflammatory cytokines, complement activation, and Fc receptor-mediated phagocytosis. These immunomodulatory effects help control autoimmune and inflammatory conditions.

Indications IVIG therapy is recommended for treatment and prevention of infections in patients with primary immunodeficiencies like common variable immune deficiency, X-linked agammaglobulinemia and hypogammaglobulinemia. It is also a first-line treatment for certain autoimmune diseases like Kawasaki disease, Guillain-Barré syndrome, chronic inflammatory demyelinating polyneuropathy and multifocal motor neuropathy. IVIG reduces symptoms and relapses in these conditions by dampening pathological autoantibody production and cytotoxic immune responses.

Administration IVIG is administered intravenously through a peripheral or central line at regular intervals. The dosage varies depending on the indication and ranges between 300-600 mg/kg given every 3-4 weeks or every 2-6 months for replacement therapy in primary immunodeficiencies. Frequent dosing is required initially for treatment of autoimmune and inflammatory conditions. IVIG is usually well-tolerated but some common adverse effects include headache, nausea, fever, chills and abdominal pain which can be managed symptomatically. Rare complications include thromboembolic events, aseptic meningitis and acute kidney injury. Careful infusion with hydration and dose monitoring helps minimize risks.

Mechanism of Action As described earlier, IVIG exerts its immunomodulatory and anti-inflammatory effects through multiple mechanisms. A major mechanism involves modulation of the Fc portion of IgG molecules. IVIG engages inhibitory Fcγ receptors (FcγRIIB) on immune cells, decreasing their activation threshold. This suppresses pro-inflammatory cytokine release and phagocytosis. IVIG also competes for binding to activating Fcγ receptors, further inhibiting immune cell activation. At the same time, exogenous IgG provides opsonization of pathogens via activating FcγRs to enhance elimination.

Additionally, IVIG binds specifically to certain cytokines and complement factors to inhibit their activity. It neutralizes interleukin (IL)-1, IL-6, tumor necrosis factor (TNF)-α and interferon (IFN)-γ which play a key role in chronic inflammation. IVIG also downregulates expression of adhesion molecules and secretion of chemokines involved in immune cell trafficking to sites of inflammation. By blocking complement activation at the C3 convertase level, IVIG prevents membrane attack complex formation and tissue damage in autoimmune diseases. These diverse suppressive mechanisms help control excessive immune responses and inflammation in various conditions treated with IVIG.

Efficacy and Clinical Trials The efficacy and safety of IVIG has been validated through extensive clinical research over the past few decades. In primary immunodeficiencies, long-term IVIG therapy greatly improves survival by preventing life-threatening bacterial infections. For Kawasaki disease, a randomized controlled trial showed IVIG plus aspirin led to a significantly lower coronary artery aneurysm rate compared to aspirin alone.

Some notable clinical trials in other conditions include a trial demonstrating that IVIG prevented relapse in Guillain-Barré syndrome; a large trial confirming clinical improvement and reduced relapses with IVIG versus placebo in chronic inflammatory demyelinating polyneuropathy; and trials establishing efficacy of IVIG in idiopathic thrombocytopenic purpura and multifocal motor neuropathy. Ongoing research continues to explore new potential uses of Human Immunoglobulin (pH4) for Intravenous Injection in various autoimmune and inflammatory diseases.