#prostatecancer
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High expression of PSMA in prostate cancer makes it an attractive target for imaging and therapy. The left image shows a Prostascint scan (indium-111-capromab, an anti-PSMA antibody) in a patient with metastatic prostate cancer (black arrow). The FDA recently approved 2 PET radiopharmaceuticals that bind the extracellular domain of PSMA (Ga-68-gozetotide and F-18-piflufolostat). The right image shows an F-18-piflufolostat scan. The superior signal-to-noise and resolution of PET allow for detection of the tiny metastatic nodes seen in the pelvis.
Image credit
Left: Bhargava et al. Am. Jour. Nucl. Med. Mol. Imag. 2012.
Right: Dr. Thomas Anderson
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Designed to provide a convenient and tasty way to support your energy levels.
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#prostatecancer#sexdrive#sleepaid#vitamind3#bloodsugar#magnesium#weightgain#sawpalmetto#periodcramps#inflammation#mentalhealth#transformation#perimenopause#musclegrowth#prostatehealth#howtolosefat#zincsupplement#proteinpowder#hormonetherapy#cognitivefunction#antiinflammatory#progesterone#medicinalherbs#fatburningpills#ftmtransgender#urinaryfunction#immunesupport#staminabooster#protectionspell#immunesystem
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How Hormone Disruptors Cause Chaos and Contribute to Cancer
Hormone disruptors are substances that can interfere with the normal functioning of the endocrine system, which is responsible for regulating various physiological processes in the body through the release of hormones. These disruptors can mimic or block the actions of natural hormones, leading to a disruption of the hormonal balance in the body. Here's how hormone disruptors cause chaos and contribute to certain cancers:
Endocrine Disruption: Hormone disruptors interfere with the endocrine system, which regulates hormone production and signaling in the body. By mimicking or blocking the action of natural hormones, hormone disruptors can disrupt normal hormone signaling pathways. This disruption can lead to uncontrolled cell growth, known as proliferation, which is the hallmark of cancer.
Cellular Effects: Hormone disruptors can directly affect the behavior of cells, including promoting cell division, inhibiting cell death (apoptosis), and stimulating the growth of blood vessels to tumors (angiogenesis). These effects can create an environment conducive to cancer development and progression.
Gene Expression: Some hormone disruptors can alter gene expression patterns in cells, leading to changes in cell behavior and function. These changes can promote cancer development by affecting processes such as cell growth, differentiation, and DNA repair.
Immune System Modulation: Hormone disruptors can modulate the immune system, which plays a crucial role in detecting and eliminating cancer cells. Disruption of immune function by hormone disruptors can impair the body's ability to recognize and destroy cancer cells, allowing tumors to grow unchecked.
Epigenetic Changes: Hormone disruptors can induce epigenetic changes, which are alterations in gene expression that do not involve changes to the underlying DNA sequence. These changes can affect how genes are turned on or off and can influence cell growth, differentiation, and cancer development.
Promotion of Inflammation and Oxidative Stress: Hormone disruptors can also promote inflammation and oxidative stress in the body, which are processes associated with cancer development. Chronic inflammation and oxidative stress can damage cells and DNA, leading to increased cancer risk. Some hormone disruptors, such as certain pollutants and industrial chemicals, have been implicated in promoting these harmful processes.
Promotion of Tumor Growth: Some hormone disruptors have been shown to directly promote the growth of existing tumors. For example, estrogen-mimicking compounds can stimulate the growth of estrogen-sensitive breast cancer cells, leading to tumor progression.
The effects of hormone disruptors can vary depending on the specific disruptor, the timing and duration of exposure, and individual susceptibility. Hormone disruptors have been associated with various health issues, including reproductive disorders, developmental abnormalities, metabolic disorders, immune system dysfunction, and hormone-related cancers.
It's important to note that reducing exposure to hormone disruptors is important for maintaining a healthy hormonal balance. More importantly, it’s crucial for those who have been diagnosed with a hormone-related cancer. This involves avoiding and/or minimizing contact with pesticides, industrial chemicals, plastics, and many home cleaning and personal care products known to contain hormone disruptors. For more information about specific products that are known to contain hormone disruptors, check out EWG.org. In addition, check out my suggestions for safe household cleaners, deodorant, and sunscreen below.
Household Cleaners
Deodorant
Sunscreen
#hormonedisruptors#prostatecancer#hormones#ovariancancer#hormonedrivencancer#breastcancer#cancer#thyroidcancer#eastwestintegrativeoncology#integrativeoncology#healthyliving#chemotherapy#ER+breastcancer
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Approximately 10-70% of kidney failure cases are attributed to overconsumption of alcohol. Stop drinking today.
#raredisease#youngcancer#kidneycancersucks#chronicillness#gastriccancer#kidneycancer#prostatecancer#allcancers#cancercare#cancerupport#kidneycancersurvivor#kidneyhealth#universitycancercenter#alcoholic#alcohol
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PSMA PET can also help DOWNSTAGE some patients. This is an example of a patient who had an enlarged retroperitoneal lymph node (red arrow). Based on CT alone, this is highly suspicious for metastasis, however, on the PET scan this is not PSMA-positive and as such is not a metastasis (note the primary tumor is PSMA-positive - blue arrow). The patient was thus staged as N0M0. Image credit: Novartis.
#TeachingRounds#FOAMed#FOAMRad#Radiology#NuclearMedicine#nucmed#PETCT#PSMA#prostatecancer#theranostics#oncology#urology
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#Abiraterone#Abirateroneacetate#Health#Howdoesabirateroneworkinthebody?#ProstateCancer#testosterone#Whatisanadverseeffectofabiraterone?#Whatisthemiracledrugforprostatecancer?#Zytiga
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Frequent testing for prostate cancer remains critical
Men’s healthcare should be under the spotlight more often, said Vanessa Snow, Head of Medical Affairs at Janssen South Africa. Differences between the sexes mean that men are more likely to suffer from a variety of conditions. Challenges that men are most likely to encounter, include diabetes, cardiovascular disease, and cancers of the prostate, testicles, and colon. Then, there’s also alopecia,…
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Men's Nighttime Wakefulness Linked to Prostate Cancer Risk | CeBoz.com
Learn about the connection between disrupted sleep and prostate cancer risk.
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Prostate Surgery in Pune: A Comprehensive Guide
The prostate is a walnut-sized gland located just below the bladder in men. It plays a crucial role in the reproductive system, producing the fluid that carries sperm during ejaculation. However, as men age, the prostate can become enlarged, causing various urinary symptoms and, in some cases, leading to more serious conditions like prostate cancer.
Prostate surgery is a common treatment option for conditions such as benign prostatic hyperplasia (BPH) and prostate cancer. In Pune, Dr. Ketan Vartak is a renowned urologist specializing in prostate surgery. With his expertise and advanced surgical techniques, he has helped numerous patients regain their quality of life.
Types of Prostate Surgery
Transurethral Resection of the Prostate (TURP): This is a minimally invasive procedure that involves removing excess prostate tissue that is causing urinary symptoms. During TURP, a thin tube with a camera and cutting device is inserted through the urethra to remove the obstructing tissue.
Open Prostatectomy: In cases where the prostate is significantly enlarged, an open prostatectomy may be necessary. This involves making an incision in the lower abdomen to access and remove the prostate gland.
Robotic-Assisted Prostatectomy: This is a minimally invasive surgical procedure that uses a robotic system to assist the surgeon in removing the prostate gland. It offers improved precision and faster recovery compared to traditional open surgery.
Radical Prostatectomy: This is a surgical procedure used to treat prostate cancer by removing the entire prostate gland and surrounding tissue. It can be performed using open, laparoscopic, or robotic-assisted techniques.
Dr. Ketan Vartak’s Approach to Prostate Surgery
Dr. Ketan Vartak is known for his patient-centered approach and commitment to providing the highest quality care. He takes the time to thoroughly evaluate each patient’s condition and develop a personalized treatment plan. His expertise in minimally invasive and robotic-assisted surgery ensures that patients experience less pain, shorter hospital stays, and faster recovery times.
Patient Testimonials
"Dr. Vartak is an exceptional surgeon who truly cares about his patients. He explained the procedure in detail and answered all my questions. Thanks to him, I am now living a symptom-free life."
"Dr. Ketan Vartak is a highly skilled surgeon. I had robotic-assisted prostate surgery, and the recovery was much faster than I expected. I highly recommend Dr. Vartak to anyone in need of prostate surgery."
Conclusion
Prostate surgery is a highly effective treatment option for various prostate conditions, and Dr. Ketan Vartak is a leading expert in the field. His patient-centered approach, advanced surgical techniques, and commitment to excellence make him the preferred choice for prostate surgery in Pune. If you or a loved one is experiencing prostate-related symptoms, don't hesitate to schedule a consultation with Dr. Ketan Vartak for personalized and compassionate care.
#ProstateSurgery#Pune#DrKetanVartak#Urology#Urologist#ProstateHealth#MenHealth#Surgery#ProstateCare#ProstateCancer#ProstateAwareness#Healthcare#SurgicalExpertise#AdvancedSurgery#MedicalCare#PatientCare#UrologyClinic#PuneUrology#PuneHealthcare#HealthAndWellness#ProstateTreatment#ProstateDoctor#SurgicalSpecialist#PuneDoctors#UrologyExpertise#SurgeryConsultation#SecondOpinion#PatientFirst#SurgicalOptions#SurgicalExcellence
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Pancreatic Cancer Treatment
In 2023 an estimated 64,050 Americans will be diagnosed with pancreatic cancer in the U.S., and more than 50,550 will die from the disease.
#diagnosed#prostatecancer#prostatecancerawareness#prostatecancerresearch#prostatecancersurvivor#prostatecancersucks#standuptocancer#cancerfree#appendixcancer#americancancersociety#cancercouncil#cancerdemama#awareness#hereditarycancer#breastcancerwalk#breastcancercampaign#fighter#universitycancercenter
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PSMA expression correlates inversely with 5-year survival in prostate cancer patients --> higher PSMA expression correlates with lower 5-year survival. Image credit: Novartis.
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How to Increase Your Immunity Naturally (By Enhancing Your White Blood Cells and Neutrophil Count)
Introduction
White blood cells and neutrophils are the powerhouse of our immunity. Unfortunately, most forms of conventional cancer treatment (i.e. chemotherapy, radiation, immunotherapy, and targeted therapies) can damage the bone marrow, causing an inadequate production of red blood cells, platelets, white blood cells, and neutrophils.
White Blood Cells and Neutrophils
White blood cells are the central part of our immune system that help our body fight against infection and disease. I like to think of them as our “family of defense.” Just like different members of a family, our white blood cells have different members with specific roles and functions. Neutrophils are one of the family members that is intimately tied to immunity. They provide the first line of defense when we come into contact with a virus, bacteria, fungus, or a parasite. Their primary task is to engulf and neutralize pathogens (that which are harmful and cause disease) through a process called phagocytosis. This rapid response helps contain the spread of infection and initiates an inflammatory cascade, recruiting other immune cells to the area. Neutrophils also release antimicrobial proteins and reactive oxygen molecules to enhance their killing capacity. Together with other types of white blood cells, they are able to create a defense network crucial for fighting disease and maintaining good health.
Regular Exercise: Physical activity has been shown to boost immune function and support overall health. Engage in regular exercise, such as walking, jogging, cycling, or swimming, as tolerated based on your individual ability and fitness level.
Stress Management: Chronic stress can weaken the immune system and negatively impact white blood cell production. It’s important to incorporate stress-reducing activities into your daily routine. Consider incorporating these into your DAILY activities: prayer, mindfulness meditation, yoga, deep breathing exercises, acupuncture, or spending time in nature.
Adequate Sleep: Quality sleep is essential for immune function and overall health. Aim for 7-9 hours of sleep per night. Here is a previous blog I wrote that might provide some helpful tips, 7 Habits for Healthy Sleep.
Diet
A well-balanced diet rich in vitamins, minerals, and antioxidants is essential for supporting immune function. Focus on consuming a variety of fruits, vegetables, whole grains, lean proteins, and healthy fats. Some specific foods that can help boost white blood cells and neutrophils include:
Citrus Fruits: Citrus fruits like orange, lemon, and grapefruit are high in vitamin C, which supports the production of white blood cells. *Please note that grapefruit interacts with a number of medications so it’s important to talk to your doctor about this in relation to your specific medications.
Leafy Greens: Spinach, kale, and other leafy greens are packed with a variety of vitamins and minerals that play a role in white blood cell production.
Garlic: Garlic contains compounds that have been shown to enhance immune function and increase white blood cell activity.
Berries: Berries such as strawberries, blueberries, raspberries, blackberries, and acai berries are rich in antioxidants that help support overall immune health.
Mushrooms: Mushrooms have strong immune-boosting properties due to their rich content of beta-glucans, polysaccharides, ergothioneine, and antioxidants like selenium and vitamin C. For thousands of years, mushrooms have been used medicinally. Extensive research has shown that mushrooms are a powerhouse food and supplement for immunity.
Ginger: Ginger has anti-inflammatory properties and may help decrease inflammation in the body, thereby supporting the immune system.
Turmeric: Turmeric contains an active compound called curcumin, which has antioxidant and anti-inflammatory properties that boost the immune function.
Green Tea: Green tea is rich in antioxidants called catechins, which have been shown to enhance immune function and protect against certain diseases.
Zinc-Rich Foods: Zinc is an essential mineral in the body that helps increase white blood cells. Foods rich in zinc include turkey meat, beef, crab, oysters, fortified cereals, and beans.
Supplements
There are many vitamins, minerals, and natural supplements that can enhance the immune system. As it relates to cancer, here are my top picks based on their ability to enhance the immune system and stimulate the production of white blood cells and neutrophils. Also, I’ve included links to research studies you might be interested in reading.
Vitamin D - Our Vitamin D level is intimately linked to our immunity and bone density. More importantly, low levels of vitamin D increase our risk for various cancers.
Vitamin D and the Immune System
The Role of Vitamin D in Cancer Prevention
Vitamin C - Vitamin C (ascorbic acid) is a key antioxidant that helps protect our cells from free radical damage. It also aids in the production of cellular energy, promotes wound healing, and helps increase immunity.
Vitamin C and Immune Function
Intravenous High-Dose Vitamin C in Cancer Therapy Vitamin C in Selected Malignant Neoplasms in Women
Zinc - As mentioned above, zinc is an essential mineral that helps stimulate white blood cell production. Zinc is an essential mineral necessary for the development and function of our immune system. It activates killer T-cells, a component of our white blood cells that is responsible for killing foreign cells, cancer cells, and cells infected with a virus. Research shows that the antioxidant properties of zinc help mitigate oxidative stress.
Zinc as a Gatekeeper of the Immune System
Role of Zinc in Immune System and Anti-Cancer Defense Mechanisms
Medicinal Mushrooms - Mushrooms have been used for thousands of years to enhance immunity. Mushrooms are high in beta-glucans, which help protect against infection. Beta-glucans have been shown to prevent cancer progression and have synergistic anti-tumor effects when combined with monoclonal antibodies and certain chemotherapies.
Immune Modulation From Five Major Mushrooms: Application to Integrative Oncology
βeta-Glucan Functions as an Adjuvant for Monoclonal Antibody Immunotherapy by Recruiting Tumoricidal Granulocytes as Killer Cells
Colostrum - Colostrum is a mother's milk produced in the mammary glands directly after giving birth. It contains high levels of protein, immunoglobulins, antimicrobial peptides, and growth factors that strongly enhance the immunity of a newborn. Research has shown that bovine colostrum, taken in supplement form, has similar effects on the immune system and can increase neutrophil count, promote immunity, and help fight infections.
Effect of bovine colostrum on the absolute neutrophil counts of Acute Lymphocytic
Leukemia patients undergoing Chemotherapy: A double-blind randomized placebo-controlled study
EGCg - EGCg (Epigallocatechin gallate) is a polyphenol antioxidant found in tea leaves, most notably in green tea. Polyphenols, like EGCg, have free radical-scavenging abilities that protect cells and tissues from damage and prevent the development of certain cancers. EGCg is also known to strongly enhance the immune system.
A Comprehensive Review on the Effects of Green Tea and its Components on the Immune Function
Green Tea Compounds in Breast Cancer Prevention and Treatment
Protective Effect of Green Tea Consumption on Colorectal Cancer Varies by Lifestyle Factors
Here are the brands of professional-grade supplements I use in my practice and highly recommend:
Vitamin D
Thorne Vitamin D 5,000
Vitamin C
Integrative Therapeutics Buffered Vitamin C
Thorne Buffered Vitamin C Powder
Zinc
Thorne Zinc Picolinate
Medicinal Mushrooms
Host Defense My Community
Colostrum
Designs for LifeTegricel Colostrum
EgCG
Protocols for Life Balance EGCg
Conclusion
Maintaining a healthy lifestyle, which includes regular exercise, stress management, sufficient sleep, and a balanced diet, plays a crucial role in enhancing our immune system. Certain dietary supplements can also provide additional support. During treatment for cancer, it is essential to take proactive steps to support your immune system. This helps to minimize the risk of infection and reduces the likelihood of developing secondary diseases.
#neutrophils#immunity#cancer#breastcancer#lungcancer#prostatecancer#coloncancer#pancreaticcancer#lymphoma#oncology#chemotherapy#radiation#immunotherapy#radiationtherapy#integrativeoncology#eastwestintegrativeoncology#yourcancerguru#nutrition#cancerdiet
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Beginners Guide To Prostate Cancer
Understanding prostate cancer is essential for early detection and effective treatment. This comprehensive guide aims to inform readers about the basic aspects of prostate cancer in a clear, clinical manner.
Prostate Cancer Basics
Prostate cancer starts in the prostate gland, which is a small walnut-shaped gland in men that produces seminal fluid. It’s among the most common types of cancer in men. However, many prostate cancers grow slowly and are confined to the prostate gland, where they may not cause serious harm.
Click on the link to read more: https://www.punarjanayurveda.com/beginners-guide-to-prostate-cancer/
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Prostate Cancer Awareness: Early Detection, Healthier Future
Being aware of the signs will help you tackle prostate cancer at an early stage. Know the signs: trouble urinating, blood in urine, bone pain. Early detection is key. Prioritize regular screenings at CBCC India for a healthier future.
#cbccindia#CancerAwareness#prostatecancer#prostatecancerawareness#menshealth#checkyourself#cancerawareness#healthawareness
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