#( promoted ) / .
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Introducing the bold new Chunga-Bunga™ and Ringo-Dingo™ sauces, available for a limited time at participating McDonalds® locations until 3/28, experience BOLD new flavors in two signature new sauces made in collaboration with Fanta to celebrate the 25th anniversary of the Power Mac G4!
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Me to my ancestors and deities: please help, I need to make more money this summer.
Me: gets promoted with more responsibilities (and yes, a little more money).
Me: ew gross not like that
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whoops I haven't posted in a week
Sorry abt that have some flowers
ILL BE BACK BUT IM SO BUSY RN
(I got promoted yippee)
#update#roses#cat#cute cats#cute animals#cats#kitties#kitty#kittens#promoted#all the tags r just so more ppl see this lovely cat :)#his name is bobby mcqueen (trust)#not my cat#i wish it was
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Aayyy guess who’s about to be promoted from her dishwashing position at work???
(I’ll give you a hint, it’s me :D)
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28. 30 ... and 4?
28. do you collect anything?
monster energy cans and junji ito books
30. what’s one thing that never fails to make you happy/happier?
getting asks on tumbly.com!
4- what’s an inside joke you have with your family or friends?
mx. wetpants
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Check out this awesome 'I'm Being Promoted To Big Sister' design on @TeePublic!
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Please stop seeing politics as an identity and start seeing it as a collective means for change
#i am so tired of ppl trying to use 'theres no ethical consumption under capitalism' in regards to BDS#it's not about ethics it's about participating in a political strategy palestinians have spent YEARS promoting as a means for change#some things are in fact not about you#social justice#I/P#social issues#palestine#gaza#free palestine#free gaza#id in alt#overflowing trashcan
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BDS added this section to their boycott page and I think people really need to read it:
[source]
please remember, pushing unorganized boycotts without carefully fact-checking every company in the list can be actively HARMFUL to the boycott movement.
#a reminder seeing that people were tagging that BDS post with companies that aren’t on the list#if you want to personally avoid a certain company the fine#but STOP promoting grassroots boycotts over the actual boycott list!!!!!
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sleeping arrangements (not sure tara would ever actually deign to sleep in the same 20ft radius as shovel but who can resist those big shiny insectoid black eyes 🥺)
plus:
#gale dekarios#shadowheart#astarion#bg3#baldur's gate 3#my art#want to promote a greater shovel presence in the fanbase. where is all the shovel content. where is my beautiful daughter#she is gale's familiar. to me.#he may not necessarily *want* shovel#but it's too late now#he's her wizard it might be more apt to say#tara is not in any way shape or form a familiar she's like. his aunt.#also i have GOT to develop a faster way of making things like i have so many dumb joke ideas i can’t be rendering shit. unsustainable! 😭😭
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USC Researchers Pioneer New Brain Imaging Technique Through Clear “Window” In Patient’s Skull
In a proof-of-concept study, a research team based at the Keck School of Medicine of USC showed that functional ultrasound imaging can record brain activity through a transparent skull implant.
— Zara Abrams | May 29, 2024
Clear experimental skull implant may enable functional ultrasound imaging of the brain for patients with serious head injuries. Photo/Todd Patterson
In the first study of its kind, researchers from the Keck School of Medicine of USC and the California Institute of Technology (Caltech) designed and implanted a transparent window in the skull of a patient, then used functional ultrasound imaging (fUSI) to collect high-resolution brain imaging data through the window. Their preliminary findings suggest that this sensitive, non-invasive approach could open new avenues for patient monitoring and clinical research, as well as broader studies of how the brain functions.
“This is the first time anyone had applied functional ultrasound imaging through a skull replacement in an awake, behaving human performing a task,” said Charles Liu, MD, PhD, a professor of clinical neurological surgery, urology and surgery at the Keck School of Medicine and director of the USC Neurorestoration Center. “The ability to extract this type of information noninvasively through a window is pretty significant, particularly since many of the patients who require skull repair have or will develop neurological disabilities. In addition, ‘windows’ can be surgically implanted in patients with intact skulls if functional information can help with diagnosis and treatment.”
The research participant, 39-year-old Jared Hager, sustained a traumatic brain injury (TBI) from a skateboarding accident in 2019. During emergency surgery, half of Hager’s skull was removed to relieve pressure on his brain, leaving part of his brain covered only with skin and connective tissue. Because of the pandemic, he had to wait more than two years to have his skull restored with a prosthesis.
During that time, Hager volunteered for earlier research conducted by Liu, Jonathan Russin, MD, associate surgical director of the USC Neurorestoration Center, and another Caltech team on a new type of brain imaging called fPACT. The experimental technique had been done on soft tissue, but could only be tested on the brain in patients like Hager who were missing a part of their skull. When the time came for implanting the prosthesis, Hager again volunteered to team up with Liu and his colleagues, who designed a custom skull implant to study the utility of fUSI—which cannot be done through the skull or a traditional implant—while repairing Hager’s injury.
Before the reconstructive surgery, the research team tested and optimized fUSI parameters for brain imaging, using both a phantom (a scientific device designed to test medical imaging equipment) and animal models. They then collected fUSI data from Hager while he completed several tasks, both before his surgery and after the clear implant was installed, finding that the window offered an effective way to measure brain activity. The research, funded in part by the National Institutes of Health, was just published in the journal Science Translational Medicine.
Functional brain imaging, which collects data on brain activity by measuring changes in blood flow or electrical impulses, can offer key insights about how the brain works, both in healthy people and those with neurological conditions. But current methods, such as functional magnetic resonance imaging (fMRI) and intracranial electroencephalography (EEG) leave many questions unanswered. Challenges include low resolution, a lack of portability or the need for invasive brain surgery. fUSI may eventually offer a sensitive and precise alternative.
“If we can extract functional information through a patient’s skull implant, that could allow us to provide treatment more safely and proactively,” including to TBI patients who suffer from epilepsy, dementia, or psychiatric problems, Liu said.
A New Frontier For Brain Imaging
As a foundation for the present study, Liu has collaborated for years with Mikhail Shapiro, PhD and Richard Andersen, PhD, of Caltech, to develop specialized ultrasound sequences that can measure brain function, as well as to optimize brain-computer interface technology, which transcribes signals from the brain to operate an external device.
With these pieces in place, Liu and his colleagues tested several transparent skull implants on rats, finding that a thin window made from polymethyl methacrylate (PMMA)—which resembles plexiglass—yielded the clearest imaging results. They then collaborated with a neurotechnology company, Longeviti Neuro Solutions, to build a custom implant for Hager.
Before surgery, the researchers collected fUSI data while Hager did two activities: solving a “connect-the-dots” puzzle on a computer monitor and playing melodies on his guitar. After the implant was installed, they collected data on the same tasks, then compared the results to determine whether fUSI could provide accurate and useful imaging data.
“The fidelity of course decreased, but importantly, our research showed that it’s still high enough to be useful,” Liu said. “And unlike other brain-computer interface platforms, which require electrodes to be implanted in the brain, this has far less barriers to adoption.”
fUSI may offer finer resolution than fMRI and unlike intracranial EEG, it does not require electrodes to be implanted inside the brain. It is also less expensive than those methods and could provide some clinical advantages for patients over non-transparent skull implants, said Russin, who is also an associate professor of neurological surgery at the Keck School of Medicine and director of cerebrovascular surgery at Keck Hospital of USC.
“One of the big problems when we do these surgeries is that a blood clot can form underneath the implant, but having a clear window gives us an easy way to monitor that,” he said.
Refining Functional Ultrasound Technology
In addition to better monitoring of patients, the new technique could offer population-level insights about TBI and other neurological conditions. It could also allow scientists to collect data on the healthy brain and learn more about how it controls cognitive, sensory, motor and autonomic functions.
“What our findings shows is that we can extract useful functional information with this method,” Liu said. “The next step is: What specific functional information do we want, and what can we use it for?”
Until the new technologies undergo clinical trials, fUSI and the clear implant are experimental. In the meantime, the research team is working to improve their fUSI protocols to further enhance image resolution. Future research should also build on this early proof-of-concept study by testing more participants to better establish the link between fUSI data and specific brain functions, the researchers said.
“Jared is an amazing guy,” said Liu, who is continuing to collaborate with the study participant on refining new technologies, including laser spectroscopy, which measures blood flow in the brain. “His contributions have really helped us explore new frontiers that we hope can ultimately help many other patients.”
About This Research
In addition to Liu, Russin, Shapiro and Andersen, the study’s other authors are Kay Jann, PhD, from the Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of USC; Claire Rabut, Sumner Norman and Whitney Griggs from the California Institute of Technology; and Vasileios Christopoulos from the University of California Riverside.
This work was supported by the National Institutes of Health [R01NS123663]; the T&C Chen Brain-Machine Interface Center; the Boswell Foundation; the National Eye Institute [F30 EY032799]; the Josephine de Karman Fellowship; the UCLA-Caltech Medical Scientist Training Program [NIGMS T32 GM008042]; the Della Martin Postdoctoral Fellowship; the Human Frontier Science Program Cross-Disciplinary Fellowship [LT000217/2020-C]; the USC Neurorestoration Center; and the Howard Hughes Medical Institute.
— Disclosure: Claire Rabut, Whitney S. Griggs, Sumner L. Norman, Richard A. Andersen, Charles Liu and Mikhail G. Shapiro have filed a provisional patent application based on this research.
#Press Release#Department of Neurologic Surgery#Homepage#Promoted#Research#USC Neurorestoration Center#Brain 🧠 | Imaging | Technique#Clear “Window”#Patient’s Skull 💀#Keck School of Medicine of USC#Functional | Ultrasound | Imaging#Skull 💀 | Implant
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Final Fantasy VII Rebirth's Director Has Been Promoted To Square Enix's Executive Staff
New Post has been published on https://thedigitalinsider.com/final-fantasy-vii-rebirths-director-has-been-promoted-to-square-enixs-executive-staff/
Final Fantasy VII Rebirth's Director Has Been Promoted To Square Enix's Executive Staff
Final Fantasy VII Rebirth, the massive sequel to 2020’s Final Fantasy VII Remake, hit PlayStation 5 back in February to acclaim from both critics and fans alike. We gave the game an 8.5 out of 10 and you can read about why in Game Informer’s Final Fantasy VII Rebirth review. Now, a little over a month since the game’s release, Square Enix has promoted Rebirth’s director, Naoki Hamaguchi, to its executive staff alongside four others joining the ranks.
The other promotions include that of Octopath Traveler series producer Tomoya Asano, Foamstars general manager Takeshi Nozue, Takayuki Hamada, and The DioField Chronicle producer Takamasa Shiba, as reported by Game Developer. These five Square Enix developers join others in the company’s executive staff, like Final Fantasy XVI director and Final Fantasy XIV producer/director Naoki Yoshida and Final Fantasy series producer Yoshinori Kitase.
[embedded content]
Here’s the full list of Square Enix executives after these recent additions:
Takashi Kiryu
Tomoya Asano
Tomoyoshi Osaki
Tsuneto Okuno
Yoshinori Kitase
Yosuke Saito
Ryutaro Sasaki
Hideaki Sato
Takamasa Shiba
Hajime Seki
Takeshi Nozue
Naoki Hamaguchi
Takayuki Hamada
Kei Hirono
Katsuyoshi Matsuura
Atsushi Matsuda
Yuu Miyake
Naoki Yoshida
For more about Hamaguchi and his latest directorial effort, read Game Informer’s Final Fantasy VII Rebirth review and then read Game Informer’s Final Fantasy VII Rebirth cover story for behind-the-scenes details and more. Be sure to visit Game Informer’s Final Fantasy VII Rebirth coverage hub for exclusive information about the game, interviews, videos, and more.
[Source: Game Developer]
Have you played Final Fantasy VII Rebirth? Let us know what you think of it in the comments below!
#Chronicle#details#Developer#developers#executives#Full#game#Interviews#it#list#Other#PlayStation#PlayStation 5#Promoted#Read#review#square#Staff#Videos
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hey! for todays protest, i made this little zine about palestine (holding just simple and basic information).
you can download the zine here, fold it yourself, and distribute it around.
no credit is needed. feel free to leave it around bars, protests, or wherever. simply print it (borderless) and fold it. here is a tutorial on how to do it.
dont stay silent. there is a genocide of horrendous, atrocious proportions going on. also if you are a zionist here to argue with me, i dont plan to entertain you at all, not on my art blog. fuck off, you'll be swiftly blocked. i see enough of you clowns on my main and i have no energy for you. you can skip the death threats too bc i dont give a shit.
(i'm off to get ready for a surgery now, i just wanted to post it before this. if you need anything, i might take a bit to reply)
#free palestine#from the river to the sea palestine will be free#anti zionisim#israel is a terrorist state#israel is an apartheid state#palestine resources#gaza#palestine#art#comics art#art zine#p.s. i usually put my socials on the end of my zines#i didnt do it here not bc i dont stand behind my words#but bc im not interested in self-promotion over palestinian dead bodies!#srsly you dont have to credit me i just hope this zine gets distributed#and as always do *not* sell this.#its a free resource based in what ive learnt from palestinians themselves#its not made for monetary or followers gain
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ohhhhhh I truly cannot get over the EVIL GENIUS of having crowley make a point of immediately taking his sunglasses off every time he's in the bookshop or alone with aziraphale this season, showing just how comfortable he's become showing his emotions and his vulnerability to aziraphale since season 1, opening himself up completely at every opportunity, showing us a side of him that's remained almost entirely hidden for millennia, only for him to silently and purposefully put his sunglasses back on immediately once aziraphale rejects his love confession. like, bravo gaiman, I saw what you did there and I'm never going to fucking recover from it. well done
#THE WAY IT WAS HIGHLIGHTED IN PROMOTIONAL MATERIAL AS WELL. WE WERE ALL SO EXCITED FOR A SEASON WITH MORE CROWLEY EYES#WE ALL NOTICED IT. WE SHOULD HAVE KNOWN.#good omens#good omens spoilers#ineffable husbands
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if genital selection becomes the next big thing in RPGs we need to push beyond a binary application of “penis” and “vulva” (even if there are additional options past that binary gate) and make a single slider. x and y axis type of thing like chusing the depth and width of your chin.
#I’m only half kidding lol I do think it’s odd that whoever made this decision is promoting it on the basis of its being#inclusive or whatever
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