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dsqelitesingapore · 3 months
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caninelymphoma-blog · 5 years
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1. Heart in a woodchipper
 9th May 2019 
A quick word about Toby (before getting into his journey):
Toby is a fighter. He lived for 14 years, of which 1 year and 5 months was a battle with canine lymphoma. He went through various types of chemotherapy, a very strict diet with various boosters and supplements, hyperbaric oxygen therapy, and countless visits to the vet which he hates. Before lymphoma, Toby was the perfect picture of health. Everyone who met him thought he was at most 7 yrs old, when he was in fact 12. We had so many good laughs when children would call out to their mom or dad saying “Look at that puppy!” or “So cute… i want a puppy too”
He brought out the best in us through the 14 wonderful years he gave us. We love him so much and hope we’ll see him again someday in heaven.
Christmas 2017 – Toby is 12.5 yrs old and weighed ~8kg here and had the appetite and energy of a champion beardog!
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“Raaaarrrr... I hate taking photos.. but i love you guys so i will put up with this.”
Nov 2017: Took Toby to the vet close by our place at Barkway Medical, due to eye discharge. The vet gave some eyedrops but noticed that Toby’s lymph nodes were swollen in both the submandibular (below the jaw, neck region) and popliteal (hind legs, behind the knees). Antibiotics prescribed. perhaps it was an infection. After a week, Toby’s lymph nodes continued to swell. Took him back for a blood test where lympocytes and neutrophils were off the charts. Doctor suggested that we check for canine lymphoma either by biopsy which means extracting an entire lymph node, or fine needle aspirate which is less invasive. We opted for FNA and hoped for the best. The test results confirmed that Toby was dealing with canine lymphoma.
At this point, it hit us really hard. Like our hearts were thrown into a woodchipper, shredded and spat out unceremoniously. Toby is a huge cornerstone of the life Junie and I built together and we love him like our own child. We reeled from the news and started googling the shit out of canine lymphoma. The prognosis for multicentric lymphoma (B-cell or T-cell) is very poor: 1~2 months if left untreated, ~6 months on average if prednisone (a type of inexpensive steroid with little side effects) is used, and on average 1 year ~14 months (for B-cell) using chemotherapy e.g. CHOP protocol (cyclophosphamide, doxorubicin, vincristine, prednisone). We were instantly thrown into a world of anguish, but wanted to believe that Toby, with help from his family, could fight this.
The doctor at Barkway tried to refer us elsewhere as they were not equipped to deal with dogs with cancer. He also mentioned that one of his staff was pregnant and for her safety would prefer if they did not have to handle cancer medication as some of it can be highly toxic. We started looking around for a vet who can help us. Natalie Prakash was mentioned by Barkway as the only certified canine oncologist in Singapore (Mt Pleasant) but the notoriety of that animal hospital made us look elsewhere. And so we began with Gentle Oak @Ghim Moh. Our friend had a good experience there for some other issue. We read the reviews and liked what we saw: holistic treatment of chemotherapy and alternative medicine. Dr.Lee in particular was more conservative on chemo dosage and advocated using other remedies. Having seen how cancer’s side effects had ravaged close friends and family and robbed them of quality of life, we decided to start with Dr. Lee.
Gentle Oak is extremely popular. Our first appointment there She started Toby on prednisone right away and scheduled Toby to come back a week later for his first dose of vincristine. We decided not to pursue finding out whether Toby’s lymphoma was B-cell or T-cell, and treated it as if it was B-cell. The reasoning behind this is, according to Dr.Lee, was that it wouldn’t make much difference in terms of the treatment. T-cell is the worst: the treatment barely works, and it’s very difficult to push it into remission; so just pray and hope that it’s B-cell which responds better to treatment and has longer remissions periods.
I will pause here .. this is the end of Chapter 1: how it first happened and how we reacted / steps we took. But… i’ve had a lot of time to reflect, and if i could turn back time I would do things differently. So, here goes.
WHAT WOULD WE HAVE DONE DIFFERENTLY?
Do not start with prednisone BEFORE Chemotherapy. Listen to this: http://www.radiopetlady.com/shows/podcast-pcv/lymphoma-importance-delaying-prednisone-chemo/   Basically the efficacy of the chemo in killing cancer cells is lowered due to prednisone. Prednisone (or prednisolone) should be given after chemotherapy begins. 
Realize that for fast spreading cancers like lymphoma it’s best that chemo is started rightaway alongside a change in diet. Dogs tolerate chemotherapy much better than human beings so fret not. Especially if your doggo is already in good shape to start off. I felt that we ought to have been aggressive with it instead of relying on alternative / holistic / natural remedies. This is not a drill. Get your act quickly and do not fear chemotherapy. In fact it’s the only thing that really beat cancer back. You will see in later chapters that we threw everything at it.
Go see Dr. Tham at Jireh Vet, Balestier. He has heaps of experience treating cancer patients, and has a much wider repertoire of treatment and a much more dynamic approach. You see, the thing about cancer is that it is constantly evolving and your dog’s immunity can be compromised in many ways that typical studies do not cover off, while undergoing chemotherapy. This causes lots of complications. Dr. Tham’s approach works because he spends a lot more time understanding each case – as opposed to super popular vets like Gentle Oak where your pet is one of the 50 patients they see therefore the likelihood of the vet fine-tuning the treatment to factor in what worked better and what didn’t for your doggo, is a lot lower. Dr. Tham isn’t running his vet to maximize profit. He’s truly interested in the better outcome.
Put your dog on a 24 hour fast with water from time to time. There’s excellent research and data around how fasting helps improve cell health and promote autophagy. it basically helps to starve off cancer cells (sensitizing cancer cells to death). The re-feeding after fasting helps activate stem cells and the regrowth of healthy cells.
Additional information on intermittent fasting and caloric restriction https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783752/
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ireviewuread · 3 years
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Using Human Stem Cells in my Skincare feat. Guna x Hitoyurai Skincare Line + Exclusive Discount
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Renew Your look with Human Stem Cells
Like the falling sakura petals, the urban lifestyle has caused us ladies to lose our youthful look faster than usual. With the stress from living in the city, we ended up ageing quickly. That’s why we need to take care of our skin and use the correct skincare products for our age group. Since I am in my mid-20s, that means it is time for me to introduce anti-ageing products to my skin. This is where Guna x Hitoyurai collaboration skin care line comes into my life. I previously raved about plant stem cells and how they are the best option for skin cell renewal for those with sensitive skin. Guna x Hitoyurai skincare line is better for they use human stem cells. 
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Guna x Hitoyurai
Guna is a renown skincare brand in Japan that have the philosophy of “Beauty, not moved by time.” This philosophy leads them to the scientific skincare concept of "skin time management" where they aim to relieve the anxiety caused by age with soft and healthy skin. Guna found out that the two major causes of skin ageing problems are saccharification and oxidation. To battle these problems, they’ve created an Anti- Oxidant & Glycation dual-antibody formula in their skincare products. To add to the greatness of their skincare formula, Guna collaborated with Hitoyurai, a Japanese Skincare company that uses human stem cells in their skincare products to renew one’s skin.
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Human Stem Cell in Guna x Hitoyurai Skincare products
Hitoyurai’s Human Stem Cell Culture Fluid Cosmetics combine fatty stem cell culture fluid and neural stem cell culture fluid creates tissue on the surface and in your skin. Unlike conventual skincare that merely ‘supplement’ your skin components, Guna x Hitoyurai Skincare products provide a fundamental solution, renewing and replenishing your skin.
Guna x Hitoyurai Skincare set helps with whitening, pigment reduction and hydration and more. Each product has its unique purposes that help with the restoration or maintenance of your skin. When you use all the products together, it’ll help you improve every aspect of your skin from dullness reduction to hydration of the skin. These products are all imported and made in Japan.
There are 6 products in the Guna x Hitoyurai Skincare Set: 
Guna x Hitoyurai Moisture Face Wash 
Guna x Hitoyurai Moisture Lotion
Guna x Hitoyurai Moisture Milk 
Guna x Hitoyurai Eye Cream 
Guna x Hitoyurai Moisture Essence 
Guna x Hitoyurai Moisture Cream
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Guna x Hitoyurai Moisture Face Wash (100ml)
Guna x Hitoyurai Moisture Face Wash helps with smooth skin and prevention of acne thorough cleansing of the skin. Its 3 main extracts help with antibacterial effect, reducing the appearance of pores and anti-inflammatory effect. 
Owlberg extract - Anti-inflammatory effect
Hydrangea extract - High Antibacterial effect
Artichoke extract - Cleanses blackheads and dirt from pores. Tightens and reduces the appearance of pores.
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Guna x Hitoyurai Moisture Face Wash Review
Upon squeezing out the face wash, it had fragrant soap scent mixed with a hint of powder. It’s a thick and velvety cream that spreads easily. You can use it with and without a foaming net. When used with a foaming net, the face wash turns into a soft and bubbly pillow that makes me feel like I’m in a cloud. When used without the foaming cleanser, the face wash feels silky when mixed with water. It glides on the skin without any resistance.
After usage, my face felt cleaner and it even looked fairer. The Owlberg extract did a good job in calming my slightly sensitive cheeks down. It is no longer as inflamed as before. I was still able to see my pores but they are insanely clean. It felt like I scrubbed these tiny holes individually. Since my blackheads have been in its original position is the dawn of time, there’s no way to remove them aside from extremely painful extraction. On the other hand, the face wash did help with the removal of artificial dirt and whiteheads on my nose.
All in all, the Guna x Hitoyurai Moisture Face Wash surprised me when it transformed my red-sensitive cheeks back to my skin’s original colour. Additionally, it does a great job in cleansing my large open pores thoroughly.
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Guna x Hitoyurai Moisture Lotion (120ml)
Made of Nature’s Hyaluronic acid, Guna x Hitoyurai Moisture Lotion moisturize the skin deeply, giving your skin a bouncy texture. It is made of two kinds of queen roses and snow fungus, a natural solution for the skin’s hydration. These nutritious ingredients improve your skin’s conditions as the lotion gets absorbed into the outermost layer of your skin easily. It also functions as a booster, allowing your makeup to last longer than before. 
How to use Guna x Hitoyurai Moisture Lotion?
Use the Guna x Hitoyurai Moisture Lotion after cleansing. 
Apply the lotion to your entire face by patting gently. 
Repeat the process and gently wrap your face within your palms.
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Guna x Hitoyurai Moisture Lotion Review
The first step after cleansing your face is to apply the moisture lotion. The Guna x Hitoyurai Moisture Lotion acts as a toner that helps hydrate and prepares your face for your multiple skincare steps. It feels like a light-weighted serum and smells like hyaluronic acid. I believe the scent is due to the higher amount of hyaluronic acid in the formula. 
Upon contact with my skin, my skin felt frosty and hydrated. The moisture lotion also starts absorbing into my skin instantaneously. During absorption, my face felt slight sticky however after the product was fully sucked into my skin, my face became matte, allowing my makeup to last longer.
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Guna X Hitoyurai Moisture Essence (30ml)
Guna x Hitoyurai Moisture Essence is a hybrid skincare product that contains human stem cell in it. It has a high concentration of both human adipose stem cell culture medium and human neural stem cell culture medium. This miracle product allows you to turn back the time on your skin in one night. The next morning,you will wake up to youthful, bouncy and smooth skin, as if you took a time machine in your dreams. 
How to use Guna X Hitoyurai Moisture Essence?
Use after applying Guna Hitoyurai Moisture Lotion.
Take a take an appropriate amount on the palm of your hand - the average is 2 pumps).
Apply the essence over the entire face gently by massaging from the centre towards the sides.
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Guna X Hitoyurai Moisture Essence Review
The Guna X Hitoyurai Moisture Essence perked my interest the most. It has a high concentration of human stem cell that helps with turning back the time on your skin. I previously raved about how much I love plant stem cells for they are rich in antioxidant and helps renew and regrowth one’s skin. Additionally, stem cells products are suitable for sensitive skin as well, thus I do not need to worry if my skin will flare up suddenly. 
When pumped out, the Guna X Hitoyurai Moisture Essence have a distinct stem cell scent that is similar to plant stem cells products. It has a consistency between a serum and a gel but leaning more towards the serum lane. The essence has a high absorption rate, seeping in my skin swiftly. The most mind-blowing thing is my face started to feel bouncier after it was fully absorbed. Of my 8 years of trying skincare products, this is the fastest I’ve ever felt a skincare product work on me. A god-like discovery.
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Guna x Hitoyurai Moisture Milk (100ml)
Guna x Hitoyurai Moisture Milk is a luxurious blend of jojoba oil, rare Argan oil and evening primrose oil, the Guna Hitoyurai Moisture Milk help create a glossy skin that is deeply hydrated and high in antioxidant. Aside from being high anti-oxidant, it also has features like sterilization and UV protection.
How to use Guna x Hitoyurai Moisture Milk?
Apply it to your skin after Guna x Hitoyurai Moisture Essence, before Guna x Hitoyurai Moisture Cream.
Take an appropriate amount and apply with lifting strokes.
Apply more to the areas of concern.
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Guna x Hitoyurai Moisture Milk Review
Guna x Hitoyurai Moisture Milk is a blend of different oils to help moisturise the skin. When I pump it out, it has a cloudy-milky look to it. It spreads across the skin easily and cools your skin at the same time. The moisture milk has a scentless cream scent to it. During absorption, it was a little sticky. After it was fully absorbed, my face not only felt back to normal but it still had the cooling sensation as well.
I did another test where I applied the Guna x Hitoyurai Moisture Milk alone to another part of my face for the whole day and I have to say, I was surprised at how moisturized I still felt at the end of the day. I was surprised that the moisture milk alone can keep my face protected from Singapore’s humidity. On top of that, despite the blend of oils in its formula, the moisture milk does not feel oily at all, perfect for those with combination skin like me.
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Guna x Hitoyurai Moisture Cream (50g)
Guna x Hitoyurai Moisture Cream is the cream you must-have if you want to battle age with grace. It helps generate lamella - a thin layer of tissue - that aids in improving skin barrier functions. Guna x Hitoyurai Moisture Cream also acts as a barrier that protects the skin from harmful air pollution such as PM2.5.    
How to use Guna x Hitoyurai Moisture Cream?
Take an appropriate amount and apply onto the entire face - 2 pearl-sized drops
Apply more to areas of concern.
Use both morning and evening.
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Guna x Hitoyurai Moisture Cream Pumps
The Guna x Hitoyurai Moisture Cream and Eye Cream have a pump design for their products. This pump design helps keep the products fresh and clean from external pollutants. . I like how you only pump out the amount you need although sometimes you accidentally press out more than expected - this happens more with the eye cream. In those cases, I take what I need for my skin and leave the rest there, gently covering the pump with the cover. If not, I would use it for the other areas of my face eg. using eye cream for smile lines.
I find that 1 full pump from the moisture cream is enough for my face and neck. If that is too little for you, you can add half a pump more. I find the design fascinating for it reminds me of jack in the box when you first use it. Like the kid that love pressing buttons, it makes me want to pump more when I see the cream come out but I have to control the child in me to prevent wastage of product.
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Guna x Hitoyurai  Moisture Cream Review
I love the design of the moisture cream for it has an interactive component of pushing the pump. It was very satisfying to be able to press the pump down fully. Since the moisture cream was suitable for both day and night usage, the cream was not as thick as other anti-ageing creams that have ceramide in it, making it suitable for oily skin victims as well. However, it was thicker than normal day cream thus suitable for dry skin sufferers. Looking at the ingredients list, it contains humectants, occlusives and emollients. That meant it was suitable for all skin types. 
Like the moisture milk, the moisture cream smell like a scentless cream. It spreads smoothly on the skin and it absorbs into the epidermis easily. The moisture cream also makes a good night massage cream for it is silky and glides on your face like an ice skater on ice. This is a great quality to have since we are to massage our face daily to promote blood circulation and look younger. 
Ever since I found out about the miraculous skincare ingredient called ceramide, I have been actively searching for skincare products with ceramides in it. If you do not know, ceramides replace skin lipids by filling in the gaps between the skin cells. That means, it helps you renew your face and maintain your youth. It is especially important to find skincare with ceramides when you’re older for your skin loses ceramides when you age thus, such products are there to help replenish your lost ceramides and can even make your skin less sensitive than before. Guna x Hitoyurai Moisture Cream is one of the esteemed products that have ceramides in it, automatically pushing its ranking to the top of my skincare list. All the products in the Guna x Hitoyurai skincare range have ceramide and other good ingredients you should look out for in it. I’ll be touching more on this part at the bottom of this post.
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Guna x Hitoyurai  Eye Cream (20g)
The skin around your eyes is the thinnest skin on your face, thus you need a special eye cream to hydrate the area. Guna x Hitoyurai Eye Cream contains plant ingredients specialised for the eye area. It is highly moisturizing, anti-glycation and provides a barrier around your eye area too. It has a unique function of resembling botox, preventing wrinkles and repair the skin around the eye.
How to use Guna x Hitoyurai  Eye Cream?
After your moisture cream application, take an appropriate amount on your ring or little finger
Gently tap the product around your eyes.
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Guna x Hitoyurai  Eye Cream Review
For me, 1/3 to 1/2 a pump is enough for my small eye area. When I over pump, I’ll tend to cover the excess with the cover so that next time I can use the cream without having to press the top. 
Guna x Hitoyurai eye cream had a very thick consistency to it, almost resembling a balm-like texture. This made it felt like a literal protective layer for my eye area. It does not have any distinctive smell to it. My eyes felt very refreshed after application. Due to its thickness, it may take longer than the other products to absorb into the skin. Additionally, it may feel a little greasy if you apply it too generously. 
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Before
Before my usage, my skin felt tight and it looked dull and dirty. The constant staying up late have taken a toll on my skin over a short period.
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2 Weeks Later
Trying out the Guna x Hitoyurai Skincare for 2 weeks has transformed my previously dull skin to a dewy porcelain skin texture. My skin looked and felt super moisturized after my skincare routine. That made me feel like I’m taking care of myself properly - you know how there seemed to be an emphasize of loving yourself correctly these days? I feel like by doing my skincare routine daily and watching my face turn bright and hydrated, makes me feel like I’m giving myself enough self-love among the hustle and bustle of one’s everyday life.
Even with the slight lightning difference, my skin did look a lot more dewier than before. So much so that it looks like its reflecting light off it. Additionally, I do look fairer than before, something I would never thought I would experience since I thought I've peaked in my skin’s paleness. 
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Guna x Hitoyurai Skincare Line Review
All in all, I love the Guna x Hitoyurai Skincare Line. My favourite product is the Guna X Hitoyurai Moisture Essence. It instantaneously transformed my skin into a trampoline. The one drawback about it would be the size of it. Why does it have to be so small?! According to the good ingredients, the Guna x Hitoyurai Skincare is perfect for people of all kinds of skin type. I am very relieved that the most sensitive area of my face - around my eye - did not get irritated by the eye cream for I previously had a bad allergic with another eye cream that I have now banned from my life. 
With that, I can safely say that Guna x Hitoyurai Skincare Line is suitable for sensitive skin. Plus, with the abundance of good ingredients in their ingredient list, you will regret not getting them. Allow me to give you a short tutorial on how to spot good ingredients in a skincare product.
Good Ingredients you should look out for in your skincare products featuring Guna x Hitoyurai Skincare Line
I’m sure you’ve heard many others advising you to look at the ingredients before you purchase a skincare product. However, most of us who are not that into skincare would not understand what the ingredients do or meant. Thus, here’s a quick lesson on what are the good ingredients you should look out for in your skincare products featuring Guna x Hitoyurai Skincare Line.
I decided to have this mini-lesson on this post because all of Guna x Hitoyurai Skincare products have these good ingredients in their list. From Ceramides to Butylene Glycol, the products have them all. People of different skin types need to take note of different ingredients so that you can get the right products that cater to your skin type. Since this post is getting lengthy, I’ll list the good ingredients found in Guna x Hitoyurai Skincare Line in point form.
Ceramide - Replace skin lipids by filling in the gaps or between the skin cells. A must-have if you are looking for effective anti-ageing products. Additionally, look for skincare products that have air-tight dispensers design so that the product would not be exposed to air or sunlight every time you open it. With air-tight dispenser designed products like the ones in the Guna x Hitoyurai Skincare Line, skincare products will work more effectively. 
Butylene Glycol - Maintains skin hydration and can temporarily plump up the skin and improve fine lines. This ingredient is popular in skincare products sold in summer countries like Singapore. Since this ingredient is very light, it helps those with oily skin type and acne-prone.
Dimethicone - Creates a barrier to prevent water loss. It is suitable for people that have dry to very dry skin. The downside of this is it will cause shiny skin but that was never a problem for me for dewy skin is in trend lately.
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Thank you for reading my lengthy but informative skincare review with a short lesson at the end. You can purchase Guna x Hitoyurai products from Btega. Every purchase through my affiliate links helps support IreviewUread and keep IreviewUread Youtube channel running.
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Get 20% off your orders on Btega
I have good news for all of you IreviewUreaders! Get 20% off you order by quoting ‘IRUR20′ on Btega. This voucher quote could be used for any products you can purchased in the store, there’s no minimum purchase needed and it lasts forever! Do note that the voucher is capped at $10 and cannot be used with other promotions/ codes. Happy Shopping!
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thrivous · 4 years
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Blood transfusions are normally used to treat severe forms of beta thalassaemia and sickle cell disease. However, three people with these inherited diseases no longer require transfusions. Their bone marrow stem cells were gene-edited with CRISPR, New Scientist reports.
A recent trial was the first to use CRISPR to treat inherited genetic disorders. And results were announced at a virtual meeting of the European Hematology Association.
“I am encouraged by the preliminary results, which demonstrate, in essence, a functional cure for patients with beta thalassemia and sickle cell disease,” said senior researcher Haydar Frangoul. The statement was in a press release issued by CRISPR Therapeutics and Vertex Pharmaceuticals Incorporated.
Artificial Eyes May Provide Superhuman Vision
Scientists led by Hong Kong University of Science and Technology have developed the world's first 3D artificial eye. It has capabilities better than existing bionic eyes. And, in some cases, it even exceeds those of natural human eyes. This brings vision to humanoid robots and new hope to patients with visual impairment.
The Electrochemical Eye (EC-Eye) is described in a research paper published in Nature. It replicates the structure of a natural eye. And it could offer sharper vision than a human eye in the future, with extra functions such as the ability to detect infrared radiation in darkness.
The key feature allowing such breakthroughs is a 3D artificial retina. It's made of an array of nanowire light sensors that mimic the photoreceptors in human retinas.
The Importance of a Strategic Mindset
Psychologists at National University of Singapore have suggested that one important psychological factor behind the achievements of successful people may be a "strategic mindset." This is the attitude of those who, in the face of challenges or setbacks, ask themselves: "How else can I do this? Is there a better way of doing this?"
A study published in PNAS suggests that a strategic mindset can be taught.
Light-Activated Molecules Kill Tumors
Chemists at Rice University have turned fluorescent tags into cancer killers. Switching one atom in the tag does the trick.
A research paper published in Chemical Science reports that replacing a single oxygen atom with a sulfur atom in a common fluorophore turns it into a photosensitizing molecule. When exposed to light, the molecule generated reactive oxygen species (ROS) that destroyed breast cancer cells in the lab.
Cheaper Compounds with Anti-Cancer Effects
Researchers at Tokyo University of Science have developed a method through which a fungal compound, capable of activating the self-destruct gene in certain cancer cells, can be artificially produced in marketable quantities. This provides a potential cancer therapeutic strategy.
In a paper published in European Journal of Organic Chemistry, the researchers describe a method to produce a compound with known anti-cancer properties. It is called "FE399." And it is naturally found in Ascochyta, a species of filamentous fungus.
According to the researchers, the newly produced compound could provide an unprecedented treatment option for patients with colorectal cancer.
Vitamin D Can Protect Against Certain Cancers
Scientists at University of Eastern Finland and Autonomous University of Madrid have found that vitamin D is beneficial both in cancer prevention and in the prognosis of several cancers.
A research paper published in Seminars in Cancer Biology indicates that the anti-cancer effects of vitamin D are especially pronounced in the prevention and treatment of colon cancer and blood cancers.
In addition, high vitamin D responsiveness can be linked to a smaller cancer risk. Vitamin D responsiveness varies between individuals, affecting their need for vitamin D supplementation.
Wireless Neural Stimulation for Neural Conditions
Rice University neuroengineers have created a tiny surgical implant that can electrically stimulate the brain and nervous system without using a battery or wired power supply.
The new neural stimulator is described in a study published in Neuron. It is based on a thin film of "magnetoelectric" material that converts magnetic energy directly into an electrical voltage.
The device worked in laboratory mice that were fully awake and free to roam. It could be used to treat epilepsy, Parkinson's disease, chronic pain, and other conditions.
Originally published at thrivous.com on June 15, 2020 at 07:04PM.
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globalteam · 4 years
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What leads to an oily scalp?
There are multiple reasons as to why a scalp can turn oily. Be it the overly reactive sebaceous glands and their increased oil secretions that lead to easier dandruff production, flakes all over, the attraction of more dirt or even giving the hair a sticky look that is all stuck up. If left untreated and uncared for, the sebum glands may clog the hair roots and cause excessive hair loss and also dandruff. The underlying causes of an oily scalp can be many.
From pollution to lack of hair care, genetic and hormonal imbalance, humidity, diet, many other factors can trigger a relatively oily scalp. In severely neglected cases of an oily scalp, dandruff keeps on increasing which may later give rise to Seborrheic Dermatitis or Scalp Eczema. So to keep an oily scalp at bay becomes one of the most important hair care routines for a person with an oily scalp.
Your fight against the oily scalp
The pioneers of the groundbreaking and revolutionary regenerative program, PHS HAIRSCIENCE® are masters in providing treatments, supplements, and hair care solutions all over the world. So say one last goodbye to all of your hair care problems with the revolutionary and the best-known PHS HAIRSCIENCE® shampoo for oily scalp in Singapore. Here’s our take at the products crafted keeping your hair type in mind.
PHS HAIRSCIENCE® – ADV PURIFY (FOR OILY SCALP AND DANDRUFF)
With no harmful ingredients, carefully chosen and balanced Korean botanical essences and stem cell technology, this PHS crafted ADV PurifyShampoo not only deep cleanses the scalp and helps remove excess oil while safeguarding the essential limit but also removes flakes and excess sebum for a fresh, healthy and inflammation free scalp.  Whatever be your scalp problems, from oily to itchy to dandruff, this shampoo helps you combat it all. For a healthier scalp and oil-free and grease-free hair that helps you boost up your confidence.
PHS HAIRSCIENCE® – ADV Purify Tonic.
For an oily scalp often only, a shampoo may not turn out to be as effective alone as when teamed up with a tonic. The ADV Purify Tonic from PHS HAIRSCIENCE® regulates the production and skin cell turnover with anti-microbial properties that not just leave your scalp healthy but also help you to fight away inflammation and unwanted hair fall. It also enhances the scalp’s ability to fight bacteria, excess oil, dandruff, and inflammation.
What are the ailments of a sensitive scalp?
Sensitive scalps can turn into dangerous painful bouts of inflammation, itching, dandruff, burning or profiling sensations. The problem with sensitive scalp is they often turn itchy and painful giving away a burning sensation.  Even seasonal changes can bring about more sensitivity. Though the underlying reasons may be varied the end result often leaves the individual in pain with quite a good amount of unwanted hair fall.
How to effectively combat a sensitive scalp?
From avoiding blow dryers to adding a tinge of extra moisture and choosing all your hair care products wisely, combating a sensitive scalp is now easily attainable.
PHS HAIRSCIENCE® – ADV Soothe Shampoo
This shampoo is apt for the sensitive scalp that goes on to make it one of the best shampoos for sensitive scalp in Singapore. It not only calms inflammation but also relieves itching and discomfort while warding off bacteria and enhancing the natural immunity of the scalp. Bottled to perfection with botanical extracts and stem cells, this shampoo helps you to get over the pangs of a sensitive scalp.
Also in the queue, you could add certain more products like:
ADV Soothe Shampoo
ADV Calming Gel
So get a special hair care regime to enhance your scalp health and boost hair growth.
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serinakemp · 5 years
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$100 Million Longevity Vision Fund Launches
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A new fund to invest in companies working on aging recently launched, the $100 millions Longevity Vision Fund. From what has been said, and what was presented at the Longevity Leaders conference, it sounds very much as though the Longevity Vision Fund principals wish to follow in the footsteps of Juvenescence, with an initial focus on small molecule drug discovery infrastructure. Unlike Juvenescence, it will probably continue to focus on established infrastructure technologies related to age-related disease, such as diagnostics, and fairly safe work with modest benefits, such as stem cell therapies, rather than invest in any of the current attempts to produce rejuvenation therapies. Whether the strategy changes later, to shift to be more in line with the rhetoric on the fund website, remains to be seen. Such a shift looks somewhat unlikely based on what is said in the article here, though the details given at the conference were more nuanced.
Inspired by British billionaire Jim Mellon, chairman of anti-aging upstart biotech venture Juvenescence, Sergey Young unveiled a $100 million fund on Monday to catalyze the development of a comprehensive solution to counteract the damaging consequences of aging. The 47-year-old considers himself a product of Peter Diamandis - the man behind the non-profit XPRIZE and venture capital fund BOLD Capital Partners - and is in charge of all things longevity at both organizations. Like Mellon, who penned Juvenescence: Investing in the Age of Longevity prior to the launch of the company Juvenescence, Young is in the embryonic stage of writing his own book designed to decode the science of aging for the masses. Meanwhile, his $100 million Longevity Vision Fund will back organizations who are working on technology to reverse the aging process and prolong healthy human life.
"We are currently working on 6 deals ... and are looking at all the usual suspects in terms of themes." These areas include early detection of serious diseases using ultrasound technology; early diagnostics for heart, cancer, and neurodegenerative diseases; stem-cell and microbiome-based therapeutics; and big data as well as AI-based applications. Unsurprisingly, Young is in dialogue with Alex Zhavoronkov's AI shop at Insilico Medicine. Zhavoronkov has deep connections in the R&D space - last year he raised funds at the behest of Shanghai high-flyer WuXi AppTec, Singapore's Temasek, Peter Diamandis, and Juvenescence.
For...
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mlmcompanies · 6 years
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The slogan, “We are the trend makers,” sets the stage for this cutting edge MLM.
And being one of the first MLMs to tackle stem cells for health and skin care products, there may be some truth to their claim.
PhytoScience is a nutritional supplements network marketing company from Malaysia that offers products based on plant stem cell technology.
They launched in Kuala Lumpur, Malaysia, in 2012, and since then they’ve actually done pretty well expanding globally.
FAQ
1. What does PhytoScience sell? PhytoScience sells stem cell products that nourish the skin from inside out and deep within—the goal being younger, healthier body cells that help you lose weight, enjoy brighter skin and a youthful appearance. The major ingredients are PhytoCellTec Malus Domestica (apple stem cells) and PhytoCellTec Solar Vitis (grape stem cells), enriched with acai berry and blueberry.
2. What are PhytoScience’s most popular products? Crystal Cell gives you phytoene and phytofluene from tomatoes that protect you from harmful free radicals from UV rays and has an anti-inflammatory effect internally. Double Stemcell is a blend of stem cell extracts found in Swiss green apples and Burgundy grapes—feeding your body from the inside out with stem cells. Triple Stem Cell H20 Moisturizer takes an outside-in approach. This moisturizer gel acts like a water network that keeps your skin radiant and youthful.
3. How much does it cost to join PhytoScience? The website says there’s no membership or expensive investment to get started. Just select the package you prefer. You can choose among the Silver Package ($93), the Gold Package ($557), a Junior Mobile Package ($1,840), and the Mobile Package ($1,854). Looks like an expensive investment to me! But conveniently, you can pay through PayPal.
4. Is PhytoScience a scam? It’s unlikely. The company has been awarded “The Largest Stemcell User” in South East Asia in 2013 and 2014, and the 14 Asia Pacific Top Excellence Brand in 2014 and 2015. It’s also very community focused, making donations to charities, associations, mosques, hospitals, orphanages, and more.
5. What is PhytoScience’s BBB rating? PhytoScience doesn’t have a BBB rating.
6. How long has PhytoScience been in business? Since 2012
7. What is PhytoScience’s revenue? RM40 million, or US $9 million, in monthly sales, as of 2015
8. How many PhytoScience distributors are there? These numbers haven’t been published anywhere.
9. What lawsuits have been filed? We didn’t see any lawsuits listed online.
10. Comparable companies: Kannaway, Total Life Changes
Competition is tough in the nutritional MLM space (see: Vida Divina) so is this one worth joining?
Product-wise this company isn’t bad, but there are better opportunities out there to make money, if that’s what you’re after.
Click here for my #1 recommendation
Either way, here’s the full review on PhytoScience.
Overview
PhytoScience sells plant stem cell products that fight aging, although their particular products are not backed by scientific studies. Their website still has goals listed from 2015 as their vision statement. [1]
Did they ever hit those goals? No one knows, because apparently, they haven’t updated their website in over a year.
However, we do know that by 2015 their monthly sales had already hit RM40 million, or little over $9 million in USD. Pretty big numbers for a company that just opened shop a few years ago. [2]
You’d think a multi-million dollar company could afford a better website. If you go to the PhytoScience website, it’s littered with all kinds of cheesy catchphrases and buzzwords.
For example, they call themselves the “TrendMaker,” claim “We’re in the business of life transformation!” and their website welcomes you with all kinds of annoying pop-ups and unwarranted music.
They even use 4 words that all start with the same letter to explain their mission. Of course they do. Their “4 Ps” are…
Produces, Plan, Platform, and People.
Not exactly revolutionary.
They were founded by a husband and wife team, Puan Sri Datin Sri Ela Tan and Tan Sri Dato Sri Lai Teck Peng. Dato Sri Lai, the company’s founder and President, has over 26 years of experience in network marketing, mostly in leadership and operational management positions.
Dude has even been bestowed an honorary title by his Royal Highness, the Sultan of Pahang. Bucket list – check. [3]
The couple recently just founded another company called Trendmaker in Singapore to take PhytoScience international. Trendmaker owns a 100% share in PhytoScience. [4]
Trendmaker was already named a prestige winner of the SME100 Awards, which is an annual award program held be Entrepreneur Magazine that identifies the fastest growing small and medium enterprises in Asia. [5]
The awards look at things like growth, turnover, profit, and market share, as well as “resilience”, which is measured by sustainability, best practices, and a company’s vision. Altogether, winning the award is a good indicator of how well your company is doing.
Products
PhytoScience sells health and wellness products reverse aging using stem cells extracted from a rare apple tree by Swiss scientists. [6]
Weird science? Check.
Rare plant or fruit? Check.
The inclusion of a European country for added legitimacy? Check.
A pill that makes you look and feel hotter? Check.
Sounds like a wellness MLM if I’ve ever seen one.
Their products come in two forms: nutrition and skincare.
Double Stemcell is their signature product, a 100% natural nutritional supplement made from the apple plant extract. They also throw in some stem cells from grapes (not just any grapes, grapes from Burgundy), acai berries, and blueberries.
Aside from nutritional products, they also sell stemcell-based skincare products called Triple Stem Cells Age Defying Solutions. These use the apple stem cells and grape stem cells, along with stem cells from the argan tree, chrysanthus flowers, and sunflowers.
They do have some credentials to back their products, at least.
Studies done by Credence Research show that plant-based stem cells can help with skin rejuvenation, weight loss, wrinkles, and skin hydration. Other than lilac and Edelweiss, the studies show that the “magic apple” (presumably the one used by PhytoScience) is one of the most popular and effective plants for stem cell nutritional products. [7]
The report also shows that sales in the plant stem cell market are expected to quadruple by 2022, so the demand is definitely there.
However, the “Swiss scientists” researching and developing PhytoScience products aren’t exactly unbiased researchers. Mibelle BioChemistry, the company that locates and extracts the stem cells for PhytoScience products, is actually a cosmetics ingredients company, so they stand to profit from selling these plant stem cells whether or not they’re scientifically proven. [8]
Compensation Plan
The opportunity and compensation as explained on their website are vague, to say the least, but that’s to be expected.
There are four ways to earn with PhytoScience:
Sponsor Bonus
Pairing Bonus
Unilevel Bonus
Matching Unilevel Bonus
However, with no description of what commission might be or how exactly these bonuses are structured, this basically means nothing. [9]
They also state that you don’t need anything to start – no membership or expensive investment. But you do need to select your preferred starter package, which implies a cost. No more details are given.
Recap
The compensation plan is virtually non-existent on the internet, which usually means it’s not great. The products aren’t bad though.
Even though the science behind their products is questionable, there is some evidence backing stem cells from this “magical” apple tree.
More importantly, for you money chasers, there’s evidence that the market for these products is going to skyrocket in the next few years regardless of the scientific claims.
That being said, who’s going to be profiting off this growing market when it comes to MLM?
You know the answer, and it’s likely not you. It’s the CEOs and the top .001% of distributors.
Look, as I’ve shown throughout this review I’m far from a PhytoScience hater. But they’re still an MLM and those have a nasty history of dropping off just a few years after being the next hottest thing.
I’m not saying it would be impossible to make money, but statistics would indicate the odds aren’t in your favor.
I’ve been involved with network marketing for over ten years so I know what to look for when you consider a new opportunity.
After reviewing 200+ business opportunities and systems out there, here is the one I would recommend:
Click here for my #1 recommendation
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kesiratb-blog · 7 years
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STEM CELL CULTURE: A MODERN MEDICINE
Stem cell is the unique sell of our body that undergoes nuclear division to produce offspring cells. These offspring cells can continue as stem cells while some become specialized cells. These stem cells have a great potential to heal a variety of disorders and injuries. These cells are present in the umbilical cord. Therefore, to combat future contingencies, cord blood is collected and stored.
In south eastern countries like India, Singapore, China, etc. cord blood banking services are provided by several organisations.
Importance of stem cells uses Stem cells have unique regenerative characteristics. They have the ability to renew themselves by cell division despite having long periods of indolence. Under specific conditions, they can become tissues and even organ-specific cells. They continuously undergo cell division to repair and replace damaged tissues. Stem cells also have the potential to help treatment of diseases like diabetes, heart diseases and various types of cancer.
Types of stem cells Embryonic stem cells, derived from the inner cell matter of a mammalian embryo. Such tissues can be developed with tissue culture.
Mouse embryonic cells are pluripotent and thus, can give rise to any type of cell in an adult organism. It is a key factor in genetic modifications.
Human embryonic stem cells are similar to mouse embryonic stem cells. They can potentially replace the patient’s defective cells.
Embryonic germ cells are derived from primordial germ cell that generates the reproductive gametes or sperms and eggs in an adult.
There are several other types of stem cells, each with their unique characteristics and usefulness.
Stem cell culture Stem cell culture would mean artificially creating an environment for the cells to survive. It would mean to ensure their validity. Several technologies and products are used to ensure their survival- Serums, supplements, filtration units, lab wares and culture wares.  These collectively help the researcher or the concerned to prepare the cell, ensure its healthy growth and thus, help in medial arenas.
Organisations step in this aspect. They provide facilities like cord blood banking wherein they collect the samples at birth, process them, conduct series of tests and preserve the cells. Therefore, it is suggested to the parents to register themselves or submit the cord blood of their offspring right after their blood, voluntarily. This would ensure a healthy and disease free life of their children in the future.
Stem Cell uses are far too many. So take time before you choose your pick.
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trigafy · 7 years
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erectiledysfunc · 4 years
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new treatment for erectile dysfunction 2016
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The goal of treatment is to restore normal sexual function whenever possible. The treatment and management of erectile dysfunction involves medications, psychological counseling, lifestyle changes, and attention to other medical conditions that may be causing dysfunction or affecting sexual function. Surgery may be an option for some men.
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ireviewuread · 4 years
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Stay Hydrated with Dione The Ideal Lab, L56 Blanche Anti-Age | Sponsored
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Our skin is the largest of the human’s body. It’s the first defence against harm's way. Therefore, we have to treat it with the utmost care to keep our defence system strong and looking youthful. However, as we age, our skin cells will generate slower. An example of decreased generation in our bodies would be Hyaluronic acid.
Hyaluronic acid is a sugar that is found in our skin. It helps us holds water and keep the skin hydrated. Like collagen and elastin, the hyaluronic acid produce by our bodies decreases the older we get. Thus, we need to replenish it with external hyaluronic acid. This external hyaluronic acid comes in the form of skincare serums or as ingredients of various skincare products. An example would be L56 Blanche Anti-age from Dione The Ideal Lab. 
Dione The Ideal Lab
Dione The Ideal Lab is an aesthetics skincare distributor that mainly distribute their products to dermatologists, skin doctors and plastic surgeons in Singapore. Their high-quality products could be purchased directly from their shop or on Shopee, Lazada and Qoo10.
Previously, I introduced Dione the Ideal Lab Series skincare bundle that includes a Hyaluron Serum, Apple Stem Cell Serum, Blanche Anti-Age Cream, Guérir la Peau Supplements and Blanche Anti-Age Bio Cellulose Stem Cell Masque. This is a no-fuss skincare set that provides you with the basics of what you need to get your skincare routine started. 
For those who are looking for a more concentrated serum for your severely dry skin, the L56 Blanche Anti-age is for you. 
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L56 Blanche Anti-Age
The L56 Blanche Anti-Age is a serum that has 56 active ingredients in it. It helps reinvigorate the skin, protects against UV-damage and reduces fine lines and wrinkles. It is good for balancing the moisture level of your skin while regenerating new skin cells. Additionally, it helps hydrate dry skin too. It is clinically tested, 100% natural and does not have any parabens, alcohol or fragrance. It’s also derived from plants. 
Each box contains 10 glass vials. Each vial is 6ml and can last for almost 2 weeks with 4 to 5 drops per usage, 2 times a day.
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The L56 Blanche Anti Age is sealed in an internally sterile glass vial. That means that this is the cleanest and freshest skincare product that you will be using in your life. Since the product comes in small doses, the vials that were not used remains new and sanitary, unexposed to any of the elements in the world.
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How to open L56 Blanche Anti-Age sealed glass vials
Pull off the plastic cover at the top, revealing the metal part. The plastic cover should also pull off a bit of the metal cover at the side.
For safety reasons, I would recommend you to use a plier at this stage. Use a plier and remove the metal part from the glass vial.
You’ll see a rubber cover left. Pluck out the rubber cover. 
Take the rubber nozzle from the box and fit it over the open glass vial. It will take some wiggling but it will fit like a glove. 
It should look like this when the rubber nozzle is tightly fitted. Remove the white cap on the nozzle when using. 
To get the product out, you have to squeeze the sides of the rubber nozzle. Replace the white cap on the rubber nozzle when not in use.
Of the 10 vials, you’ll get 2 rubber nozzles so you are to reuse them. You could also reuse these glass vials for DIYs and display purposes once you check out my quick tutorial on how to remove the silk screen printing from the glass.
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Dione The Ideal Lab, L56 Blanche Anti-Age Review
The L56 Blanche Anti-Age is a handy travel-sized serum that is easy to use and keep. It is light weighted and cool upon touch. The serum is not sticky after absorption and it makes the area feel smooth and refreshing. It smells like hyaluronic acid. When in contact with dry skin, one instantly feels moisturized once absorbed. 
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Before using Dione The Ideal Lab, L56 Blanche Anti-Age
As I had gone through the 14 days with Dione the Ideal Lab skincare routine before I tried the L56 Blanch Anti-Age, my skin was in good shape when I started trying out the L56 Blanche Anti-Age. Aside from the hormonal acne on the side of my face, I did not have much to complain about.
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After using Dione The Ideal Lab, L56 Blanche Anti-Age 
It took almost 2 weeks to finish 1 glass vial. I was using the serum twice a day, every single day without fail. Upon further inspection, my face did look slightly fairer. This was a surprising discovery to me for I’ve always thought that the main focus of this serum is to increase the hydration level of my skin. In an extension of that, my previously dry U-zone felt much more hydrated and lively. In the past, areas of my cheeks will feel tight by the end of the day. However, using the L56 Blanche Anti-age have maintained the hydration level of my skin throughout the day.
I am currently on my fourth vial of L56 Blanche Anti-Age and my skin has never felt so plump. It’s soft, it’s healthy and it almost feels like I have a water park underneath my skin.  
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You can get the L56 Blanche Anti-age from Dione International’s online shop. You can also check out more about Dione International Singapore on their Facebook and Instagram. 
Quote "ireviewureadsh#03" on Dione International’s shop to help support my platforms while you take care of your skin.
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erectiledysfunc · 4 years
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Erectile dysfunction (ED) is a highly prevalent problem that affects the. to interval aerobic exercise on a treadmill, in a high-intensity protocol,
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The treatment protocol consisted of one treatment sessions per week for 6 weeks, a 6 -weeks no-treatment. erectile dysfunction, ESWT, E.D. medical treatment.
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A host of reporters argued on Twitter that Navarro’s decision to bypass White House protocol and publish an op-ed attacking the federal government’s top infectious disease expert would have gotten.
Two former LSU students claim they were raped by former Tigers star running back Derrius Guice when he was a freshman at the.
The Enforcement Directorate (ED) on Wednesday conducted multi-city searches in connection with a money laundering case filed.
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 · Erectile dysfunction is an umbrella term for any disorder that makes it difficult to develop or maintain an erection during normal sexual activity. Frequently, ED is caused by other disorders, such as diabetes or cardiovascular disease.
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Cast in the context of the coronavirus pandemic, the clustering and close-fought commotion of the NHL playoffs might seem.
There is lack of evidence-based protocol for Low -intensity Shockwave Therapy (LiST) for erectile dysfunction (ED). Furthermore, safety and efficacy of repeating shockwave therapy has not been explored. This 2-phase study a) compares the efficacy and.
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is vitamin e good for erectile dysfunction erectile dysfunction bands ginseng tablets for erectile dysfunction Mission Statement: Evidence-based Complementary and Alternative Medicine (eCAM) is an international, peer-reviewed journal that seeks to understand the sources and to encourage rigorous research.Erectile Dysfunction (ED) (or according to the new classification, DSM-5, erectile dysfunction) is a disorder in which a man can not achieve or maintain erection until the end of sexual activity for six months in most sexual activities in which he participated.Some of the signs that indicate the possibility of low sperm count are pain in the testicles, erectile dysfunction and low.
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erectiledysfunc · 4 years
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Surgery often cuts these; radiation frequently damages them. A special surgical approach called nerve-sparing prostatectomy can push your ED risk below that of .
Stem cells help some men with erectile dysfunction after prostate surgery. This article is more than 3 years old. In clinical trials, eight out of.
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June is Men’s Health Month, a time for us to consider what we’re doing to stay healthy. In addition to eating right and.
Radical prostatectomy (RP) is the gold standard approach to cure and. Patients with pre-existing ED, type 1 diabetes, prior prostate surgery,
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The true incidence of erectile dysfunction (ED) after prostate cancer therapy is unknown, and the rates of ED in radical prostatectomy (RP) and.
Prostate cancer surgery may cause weakness in the pelvic floor muscles and the. erectile dysfunction (ed) following major pelvic surgery is not uncommon.
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Surgery to remove the prostate gland (radical prostatectomy) can cause. Ask them to refer you to your local Erectile Dysfunction Clinic if they are not able to.
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Erectile dysfunction following radical prostatectomy for clinically localized prostate cancer is a known potential complication of the surgery.
Side effects from having surgery for prostate cancer are common. They don't happen in all men, but some men can experience complications such as erectile.
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June is Men’s Health Month, a time for us to consider what we’re doing to stay healthy. In addition to eating right and.
When a man ejaculates before, during or within three minutes of penetration during sex, it is termed premature ejaculation.
While some health benefits of intercourse-like better mood and sleep-may seem like a given, there are some additional.
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erectiledysfunc · 4 years
Text
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Contents
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Erectile Dysfunction (ED) is a medical condition that prevents a man from getting or keeping an erection.
natural things for erectile dysfunction Arousal starts in the brain, but it also involves the nerves, muscles and blood vessels, and can be impacted by hormones and emotions. If a problem develops with any of these things, erectile dysfunction could be the consequence. generally speaking, causes for erectile dysfunction can be divided into two categories: physical and psychological.
In fact, more than half of men over 70 years old experience some symptoms of ED. 2) Sedentary lifestyle. I know. You probably already know that.
SINGAPORE – The Health Sciences Authority (HSA) has warned the public to avoid buying or consuming two products as they contain potent medicinal ingredients that should not be used without medical.
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Common pelvic pain conditions include: erectile dysfunction. experiencing the symptoms described here, reach out to one of these experts to help determine the true cause of your symptoms.
DR ELLIE CANNON offers her guide to dealing with the male ailments you might be shy to talk about – but really needn’t be,
Your friend has seen tons of pop culture references about erectile dysfunction and. ejaculation in order to get to the root cause so the dysfunction can be addressed. Your friend should.
Considering taking medication to treat erectile dysfunction? Below is a list of common medications used to treat or reduce the symptoms of erectile dysfunction. Follow the links to read common.
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Erectile dysfunction (impotence) is the inability to get and keep an erection firm enough for sex. Having erection trouble from time to time isn't.
Sexual symptoms could be an early warning sign of worsening health status. Erectile dysfunction, also known as impotence, is characterized by the inability to develop or maintain an erection of.
Testosterone is responsible for the improvement of male sexual characteristics and this hormone formed by the testicles. It is also important to maintain various functions such as sexual function,
Certain psychological or emotional issues. Psychological or emotional factors may make ED worse. You may develop ED if you have one or more of the following:.
Other Conditions that Can Cause Impotence Many things can lead to ED. Stress, depression, anxiety, and alcohol use often trigger it. In other cases, physical.
source https://www.erectiledysfunction-pills.com/erectile-dysfunction-symptoms-and-causes/
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