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Basal cells: Location: Basal layer of all epithelia. Characteristics and function: Stem cell regenerative compartment for epithelial structures. Shape and size: Small round cells with a high N:C ratio. Nucleus: Round (a) to ovoid (b) centrally placed with compact chromatin. Cytoplasm: Scant with mild basophilia (c). Cytoarchitecture: Pavement (d) or columnar. Ddx: Matured lymphocytes. #vetpath #vetpathology #vetpathologist #vetcytology #vetcyto #veterinaryclinicalpathology #vetclinpath #veterinarycytology #veterinarycytopathology #veterinarymedicine #vetlabdiagnostic #vetcases #vetlife #normalcaninecell #basalcell #vetlablife #veterinary_medicine #vetmed https://www.instagram.com/drdashvetpath/p/BweUHo2Bi7J/?utm_source=ig_tumblr_share&igshid=1hu6g0s917um0
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Melanocytes Location: Pigmented areas of body. Characteristics and function: Melanin producing cells of the body. Associated with epidermis, mucosae and serosal surfaces. Shape and size: Medium sized with pleomorphic morphology and no defined cellular limits (a) Cytoplasm: Abundant, faint Basophilic (c), large numbers of dark fine melanin granules (d). Nucleus: Large, round, central with fine stippled chromatin (b). Background: Free melanin pigment. Differential: Melanophage. #vetpath #vetpath #veterinaryclinpath #veterinarypathology #veterinarycytopathology #veterinarycytology #vetcytology #cytology #cytologyvet #cytologystuff #normalcaninecell #normalcell #melanocytes #melaningranules https://www.instagram.com/drdashvetpath/p/BwRCJnNhCkM/?utm_source=ig_tumblr_share&igshid=v1hiuv0kzaws
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Ciliated epithelial cells: Location: Respiratory mucosa, conjunctiva Function: Lining of mucous membrane. Sweeping action of cilia helps in clearing out dust particles and debris. Shape: Elongated, columnar and wavy (a). Size: Medium sized cells seen sometimes with nucleus protuding out (b). Cytoplasm: Moderately Basophilic (g), apical ciliary apparatus (k), focal hyper basophilic area (h), superficial eosinophilic zone (i) and cilia (j). Nucleus: Round (e), oval (f), subterminal with fine stippled chromatin. Cytoarchitecture: Exfoliate as individual cells. Background: Mucinous matrix #vetpath #veterinarypathology #veterinarycytopathology #vetcytology #veterinarycytology #normalcell #cytopathology #normalcaninecell #respiratoryepithelialcells #ciliatedepithelium #ciliated #ciliatedcolumnarepithilium #hairycells https://www.instagram.com/drdashvetpath/p/BwHM6l0hvmM/?utm_source=ig_tumblr_share&igshid=1xzqjs1fbr0mv
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Conjunctival squamous: Location: Bulbar conjunctiva. Shape and size: Intermediate to superficial cells. Polygonal with a low N:C ratio. Characteristics: Epithelial cells of the bulbar conjunctiva. Nucleus: Centrally placed with compact fine chromatin (a) Cytoplasm: Clear, amphophilic with melanin pigments in perinuclear area (b). Cytoarchitecture: Single or in clusters. #vetclinicalpathology #vetpath #vetpathology #vetcytology #veterinarypathology #vetopthalmology #veterinaryclinicalpathology #veterinarycytology #veterinarycytopathology #normalcaninecell #normalcell #normalcytology #conjunctivalsquamouscell #eyecell https://www.instagram.com/drdashvetpath/p/BwB1X7OBjRi/?utm_source=ig_tumblr_share&igshid=lohfxwr2i8cg
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Luteal cell: Location- Female genital tract, #ovary #corpusluteum Characteristic and function - Production of #progesterone and formation of #corpusluteum Shape - Pear shaped Size - Vert large to large Cytoplasm - Basophilic (c) and abundant with empty vacuoles (d). Nucleus - Large (a), oval round, central to paracentral with finely stippled chromatin and prominent nucleolus (b). Cytoarchitecture - Pavement clusters or single cells. #vetpath #veterinarypathology #cytology #vetcytology #veterinarycytology #veterinarycytopathology #cytopathology #cytopath #normalcell #vetdiagnosis #impressionsmear #diffquick #diffquikstain #ovariancell https://www.instagram.com/drdashvetpath/p/Bv3Da3fhMdM/?utm_source=ig_tumblr_share&igshid=1pugr3qr10uxs
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Granulosa cells: Location: Female genital tract, ovaries. Function: Oocyte maturation and support. Nucleus: Eccentric, polygonal with reticular chromatin (a) Cytoplasm: Scant and basophilic (b), sometimes seen with empty vacuoles (c) Cytoarchitecture: Small pavement clusters (d) Ddx: Lymphoblasts #vetpath #veterinarypathology #vetcytology #veterinarycytology #cytology #cytologyvet #cellcytology #cellsundermicroscope #ovariancells #granulosa #granulosacell #cytodiagnostic #normalcell #cytologicalexamination #impressionsmear https://www.instagram.com/drdashvetpath/p/BvbzxP_hfQb/?utm_source=ig_tumblr_share&igshid=j6zcavgyj9ew
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Smooth muscle cell: Location: Involuntary muscle tissue if many organs Function: Mesenchymal cells for involuntary muscle contraction. Shape: Elongated and thin Cytoplasm: Eosinophilic (c) Nucleus: Cigar shaped (b), elongated and thin (a) Ddx: Fibrocytes #vetpath #veterinarypathology #cellcytology #vetcytology #veterinarycytopathology #veterinarycytology #fna #fnac #fineneedleaspirationcytology #fineneedleaspiration #fineneedleaspirate #smoothmuscle #smoothmusclecells #mesenchymalcell https://www.instagram.com/drdashvetpath/p/BvZ-a3xBMYo/?utm_source=ig_tumblr_share&igshid=1codzb9tdhe3s
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Canine adipocyte: Characteristic: Fat storing mesenchymal cells. Shape and size: Large Signet ring shaped cells with a low N:C ratio. Cytoplasm: Large optically empty cytoplasm (b) with occasional cracking and folding (c). Nucleus: Peripherally located with compact and condensed chromatin (a). Cytoarchitecture: Solid cytoarchitecture intertwined with fibrotic material and blood vessels. Ddx: Sq. epithelial cells, adipophage, large macrophage. #cellcytology #vetdiagnostics #vetcytology #cytology #cytodiagnostic #vetpath #veterinarypathology #fna #fnac #adipocytes #adiposetissue #subcutaneousfat #fattytissue #fatstoringcell #fatdepots #fattydeposit https://www.instagram.com/drdashvetpath/p/BvV-a2NhNgH/?utm_source=ig_tumblr_share&igshid=khi2lb0bqif3
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Epidermal cyst with pyogranulomatous inflammation in a dog: As seen in the images many polymorphonuclear cells are seen surrounding the irregular dark basophilic material. Multinucleated foreign body giant cells along with variable number of macrophages can also be observed in aspirates. The dark basophilic material seen are aggregates of keratinized materials which have been ruptured from the cyst into the surrounding tissue. A inflammatory response is set by the host to clear out the debris along with keratinized materials out of the involved tissue. #vetpath #vetpathology #veterinarypathology #veterinarypath #vetclinpath #veterinaryclinpath #veterinaryclinicalpathology #vetclinicalpathology #cytology #vetcytology #veterinarycytology #aspirate #aspirationcytology #aspirate #vetlabdiagnostic #veterinarylabdiagnosis #cytologicalexamination #cytologylab #cytologyvet #fnac #fna #caninetissue #epidermalcyst #dermatology #vetdermatology #veterinarydermatology https://www.instagram.com/drdashvetpath/p/BvGNW39h3R-/?utm_source=ig_tumblr_share&igshid=16c5bpw8m5clt
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