i am never ever taking any medical product that has had no human trial and neither should any of you unless you are at high and immediate risk of death or disability

pfizer's own press release from sept. 11th, 2023

'pre-clinical' means non-human studies. and believe me, if they had any halfway decent clinical human trial data to include in their application, they would definitely not even mention these preclinical studies (in rats or mice most likely) to begin with.

'previous clinical and real-world evidence' refers to the original vaccine (rushed human trials), and the previous bivalent booster (no human trials before market release) formulated for a different strain. just because regulatory agencies have agreed to accept the little trick of the updated vaccine not being 'different enough' to warrant new trials, does not mean it is not. remember this difference is significant enough for the new strain to evade any existing immunity.