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Sequence of TB infection in kidney.

Stenosis of calyceal neck or pelvic ureteric junction → Hydronephrosis and pyonephrosis → Perinephric abscess → Kidney replaced by caseous material (puty kidney) → Calcifcation → Autonephrectomy (a calcifed non-functioning kidney, representing end-stage disease).

Autonephrectomy is the fnal result of marked parenchymal fbrosis and obstructive uropathy.