Particle Size Reduction: High Shear Mixing vs. High-Pressure Homogenization
High shear mixing and high-pressure homogenization are both effective methods for particle size reduction, homogenization, and emulsification. Here’s a quick rundown:
Shear Force: It's a parallel force to a material's surface, creating friction in liquids and reducing particle size. High shear mixers use high-speed blades or a rotor-stator setup to generate this force. High-pressure homogenizers propel samples through a narrow tube or orifice, generating shear and additional forces like collision impact and cavitation.
Pros and Cons:
High Shear Mixing:
Handles larger volumes and more viscous samples.
Generally more affordable.
Better for larger beginning particle sizes.
High-Pressure Homogenization:
Achieves narrower distribution and smaller particle sizes.
More precise and faster processing.
Provides uniform results since all samples undergo the same process.
Some applications benefit from starting with high shear mixing to reduce initial particle size and then finishing with high-pressure homogenization for finer, uniform results.
Conclusion: Choose based on your needs—larger volumes and cost efficiency vs. precision and uniformity.
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NanoGenizer 고압균질기는 공급용 저장탱크, 고압 펌프, 변환기, PLC 제어 패널 및 마이크로플루이딕스 다이아몬드 상호작용 챔버로 구성되어 있습니다. NanoGenizer 고압균질기의 위생 펌프 시스템은 제품 스트림에 원하는 압력을 공급하고, 이를 마이크론 챔버(마이크로리액터)를 통해 푸시하여 스트림 내에서 고전압 전달과 강력한 충돌을 유도합니다. 이 과정은 균일한 입자 분포와 더 작은 입자 크기를 유발합니다.
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Comparing High-Pressure Homogenization (HPH) and Sonication for Liquid Formulations
Homogenization is a critical step in various industrial processes, including pharmaceuticals, food, and cosmetics. High-pressure homogenization (HPH) and sonication are two commonly used homogenization techniques. However, HPH offers several distinct advantages over sonication.
Smaller Particle SizesOne of the most significant advantages of HPH over sonication is its ability to produce smaller…