#peptides | Explore Tumblr Posts and Blogs

testoster0ne · 1 year

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connor

#testosterone #roid #male #gains #anabolic #aesthetic #shredded #jacked #fitness #video #zyzz #protein #peptides #muscular #alpha

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miss-biophys · 3 months

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New publication out!

We were curious what happens with the lipid membrane if proteins are inside. As a model of membrane proteins we use transmembrane peptides with neutral and positive charge. The charges turn out to be quite crucial in the peptides influence on the lipids.

publication link: https://doi.org/10.1016/j.colsurfb.2024.113765…

All transmembrane peptides hinder mobility of lipids around. The positive charges in the peptide make this hindering a long range influence.

The membrane with the positive peptides then has heterogeneities in the lipid mobility. This hampers free rearrangement of lipids and leads to lower ability to seal ruptures. You can see below how the membrane stays fragmented after indentations with AFM (atomic force microscope), which is basically a very tiny tip that scans the surface of the membrane for images and can also push through it to test mechanical stability.

For comparison this is how it looks like with a membrane without any peptides. The mebrane seals the ruptures induced by the AFM tip and recovers its round shape. The same happens if we have a neutral, non-charged, peptide.

With this work we highlight the importance of including charges of proteins and peptides in membrane model studies.

And last but not least...

This is the very first time I am the last corresponding author of a publication. I am immensely proud on myself!

#science #women in science #research #biophysics #afm #fluorescence #simulations #peptides #proteins #cell membranes #publication #collaboration #corresponding author #proud #original content

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mindblowingscience · 1 year

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In a study published in the peer-reviewed Science Advances journal, researchers from Rutgers University say a peptide containing nickel atoms may have sparked life on Earth.

A peptide is a molecule made up of short chains of amino acids, which are the molecules that form proteins. This particular peptide has two critical nickel atoms bonded with its nitrogen atoms, leading scientists nickname the molecule "Nickelback."

Members of the university's Evolution of Nanomachines in Geospheres and Microbial Ancestors (ENIGMA) team were researching how proteins might have been able to kickstart life on earth, specifically looking for a chemical that would be simple enough to have been around in the early stages of life yet chemically active enough to absorb energy from the environment to create life.

Scientists analyzed complex proteins that, while they were too advanced to have emerged so early on, have been linked to the metabolic process of transforming small molecules. By looking at the base of these proteins, they concluded Nickelback may be a "pioneer peptide."

#science #stem #biochemistry #life #peptides

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pinkrhode · 3 months

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The Rhode phone case ? Are you kidding 😫 a need !

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life-and-skincare2survive · 17 days

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A mix of moisturizers, toners and serums that your skin will LOVE! sometimes your skin can be dehydrated or dry and these will help combat that.

some ingredients that help are- 1. hyaluronic acid, 2. panthenol, 3. glycerin, 4. squalene 5. peptides etc.

the products listed have some to most of these ingredients can can help quench your dehydrated skin!

happy skincare!

#skincare #skincare routine #skincare tips #glowingskin #self improvement #skin treatment #self care #cosmetics #dry skin #dehydrated #peptides #hyaluronic acid #hydrated skin #glowy skin #face serum #moisturizer

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naileadevoras · 3 months

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#rhode skin #peptides #lip treatment #coquette #pink

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jesus-died-for-mycins · 10 months

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Back at it again with another funky way to make funky peptides, gotta admit I have a type. The authors didn't provide a scheme but I whipped one up anyways :)

This time the approach is to forgo the traditional cyclisation methods (chemical ligation or disulphide bridging) and instead cyclise the peptide via a click reaction. So, what is a click reaction and why bother? Well click chemistry is the nickname given to a series of biorthogonal (meaning it doesn’t interfere with biological systems) azide-alkyne coupling reactions developed by Bertozzi, Meldal and Sharpless, its kinda a big deal and those folks won the 2022 Nobel prize for their work. There are a few reasons it would be useful to cyclise a peptide with click chemistry, a) its an orthogonal reaction which means that previously inaccessible functional groups could be included in cyclic peptides, b) a lot of ink has been spilled optimising, developing and expanding click chemistry so there’s a massive array of options and flexibility for future development, c) the click reaction produces a far more stable product that disulphide bridging and d) its not confined to the N/C terminus like chemical ligation usually is.

So with the background out of the way, what did these folks actually do? Well the paper is describes a protocol for creating cyclic peptide probes; i.e. a cyclic peptide that will bind to a target and is functionalised with a reactive handle so it can be visualised via a fluorophore. The paper is detailing a quite specific protocol, and what I think likely happened is that these folks were trying to create probes for their other research, but they realised the method they came up with was so effective that they should really publish it as a protocol (this would not be unusual).

But anyways, onto the chemistry. To create cyclic probes the researchers incorporated 2 orthogonal click reactivities into the linear sequence, a thiol-ene reaction to generate the cycle and a classical azide-alkyne for the probe functionality. The scheme does all the talking really (and was a bitch to draw) but nonetheless I think that it’s a neat demonstration of the expanding tools available for synthesising tricky peptides and versatility of click chemistry.

References:

LeValley PJ , Ovadia EM , Bresette CA , Sawicki LA , Maverakis E , Bai S , Kloxin AM . Design of functionalized cyclic peptides through orthogonal click reactions for cell culture and targeting applications. Chem Commun (Camb). 2018 Jun 19;54(50):6923-6926. doi: 10.1039/c8cc03218a. PMID: 29863200; PMCID: PMC7433322.

#peptides #science #stem #chemistry #click chemistry #phd #stemblr

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youngpeptide · 1 month

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Peptides & HGH

Order contact: Whatsapp/Telegram/Signal:+86 17039595306 Email:[email protected]

Semaglutide CAS No.910463-68-2 Tirzepatide CAS:2023788-19-2 Retatrutide CAS No.:2381089-83-2 Liraglutide CAS No.:204656-20-2 Cagrilintide AOD9604/HGH Fragment 177-191 Selank Semax SS31/Elamipretide PT141 Epithalon Tesamorelin Thymosin alpha 1 MOTS-C Thymulin LL-37 Oxytocin PEG-MGF DSIP Hexarelin Sermorelin MGF Triptorelin CJC-1295 NO DAC (MOD GRF 1-29) CJC-1295 DAC GHRP-2 GHRP-6 MT2 (Melanotan II) MT1 (Melanotan 1) HGH IGF-1 LR3 HCG HMG BPC 157 TB500 Ipamorelin HGH Fragment 176-191 Dihexa PMK ethyl glycidate CAS No: 28578-16-7 1,4-Butanediol BDO CAS No.:110-63-4

#buildingbody #health & fitness #fitness #bodybuilding #weight loss #semaglutide #peptides #gym #gym body #tirzepatide #retatrutide weight loss #liraglutide #Cagrilintide

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thephixcare · 4 months

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How to Apply Peptide Serum on Your Face?

Peptide serums have become the talk of the town in skincare, promising a radiant and youthful complexion. You're in the right place if you've ever wondered about the magic behind peptide serums and how to integrate them into your daily routine. In this comprehensive guide, we'll explore the wonders of Peptides Serum and provide you with a user-friendly step-by-step guide on how to make the most out of these skincare essentials.

What are Peptides?

Imagine microscopic superheroes patrolling your skin, stimulating collagen production, and fighting off wrinkles. That's exactly what peptides do! These short chains of amino acids are the building blocks of protein, including collagen, elastin, and keratin – the holy trinity of youthful skin. As we age, our natural production of these proteins dwindles, leading to fine lines, wrinkles, and loss of elasticity. But fear not, peptide serums come to the rescue!

Discovering the Best Peptide Serum for Your Face

The market is flooded with various peptide serums, each claiming to be the best. To navigate this sea of options, look for a peptide serum that suits your skin type and addresses your specific skincare concerns. Best Peptide Serum For Your Face by The Phix understands the transformative power of peptides. This is a carefully crafted elixir that targets fine lines, wrinkles, and loss of elasticity, leaving your skin feeling like a dewy dream. Formulated with potent peptides serum like this, this innovative serum works at a cellular level to boost collagen production, plump your skin, and smooth away visible signs of aging.

How to Apply Peptide Serum on Your Face?

Here's how to incorporate the Peptides Serum into your skincare routine for maximum impact:

Step 1: Cleanse Your Face

Start with a clean canvas. Use a gentle cleanser to remove any impurities, makeup, or excess oil from your face. Pat your skin dry with a clean towel to enhance the drying process.

Step 2: Tone Your Skin

Apply a suitable toner to balance your skin's pH levels. This preps your skin to better absorb the peptides serum.

Step 3: Dispense the Peptide Serum

Carefully dispense the recommended amount of peptide serum onto your fingertips. A pea-sized amount typically covers the entire face adequately.

Step 4: Dot the Serum

Gently dot the peptide serum on different areas of your face – forehead, cheeks, nose, and chin. This ensures even distribution.

Step 5: Massage In Upward Motions

Using upward and outward motions, massage the serum into your skin. Handle with care, especially around the delicate eye area. Allow the serum to be absorbed fully before proceeding to the next step.

Step 6: Follow with Moisturizer

Seal in the goodness of the peptides serum by applying your favorite moisturizer. This step helps lock in hydration and enhances the overall effectiveness of your skincare routine.

Step 7: Apply Sunscreen

Always conclude your morning skincare routine by applying a broad-spectrum sunscreen with a minimum SPF of 30. This protects your skin from harmful UV rays and prevents photoaging.

Conclusion:

In the quest for timeless beauty, The Phix Peptides Serum emerges as a frontrunner. By following this comprehensive guide on how to use the Peptides Serum for the Face, you're on your way to unlocking radiant, youthful skin. Invest in the Best Peptide Serum, embrace a consistent skincare routine, and let the magic of peptides transform your complexion. Your journey to a more radiant you begins now!

More Resources

#peptideserum #peptides #skincare #benefits of peptides for skin #beauty #thephix

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testoster0ne · 2 years

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anthony

#strong #alpha #male #aesthetic #testosterone #anabolic #peptides #gains

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aasraw-mary · 9 months

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5 Best peptides for Weight Loss

1 Best Peptide for Weight Loss: Semaglutide

Semaglutide belongs to a class of medications known as glucagon-like peptide-1 receptor agonists, or GLP-1 RAs. It mimics the GLP-1 hormone, released in the gut in response to eating. The Semaglutide injection works by slowing down how quickly food leaves your stomach and allows you to feel full for a longer period of time. By reducing hunger, lowering your appetite and increasing feelings of fullness, it will reduce your calorie intake and allow you to lose weight, 1-2 pounds a week.

2 Peptide for Weight Loss: Tirzepatide

Tirzepatide is a novel medication that is FDA approved for the treatment of type 2 diabetes mellitus. Given its potent weight loss properties, tirzepatide be used off-label for obesity treatment. It works as a dual GLP-1 agonist and GIP agonist to maximize similar benefits that are seen with GLP-1 medications such as semaglutide. It is currently implemented as a second-line diabetes medication, similar to GLP-1 medications, and given as a once-a-week subcutaneous injectable.

3 Peptide for Weight Loss: Liraglutide

Liraglutide, is an anti-diabetic medication used to treat type 2 diabetes, and chronic obesity. It is a second line therapy for diabetes following first-line therapy with metformin. Its effects on long-term health outcomes like heart disease and life expectancy are unclear. It is given by injection under the skin.

5 Peptide for Weight Loss: Retatrutide

Retatrutide is an agonist of the glucose-dependent insulin otropic polypeptide, glucagon-like peptide 1, and glucagon receptors. As can be expected, such a significant reduction in body weight in overweight and obese people also resulted in an improvement in blood pressure, cholesterol, and glucose parameters.

How do Peptides for Weight loss Work?

Most of the peptides, if not all, work via a common mechanism of action. They increase the release of Growth Hormone from the anterior pituitary gland, which leads to systemic effects. This is primarily seen in peptides used explicitly for muscle growth and endurance.

As far as weight loss peptides are concerned, it gets pretty interesting!

Some of these peptides work by increasing growth hormone levels. The growth hormone, in turn, targets specific sites like adipocytes and hepatocytes, causing raised cellular metabolism and fat burning.

Besides this, most peptides also work by rapidly increasing the process of lipolysis and simultaneously inhibiting excess lipogenesis from occurring. This leads to a net loss of fat.

A few peptides also work by regulating hormones responsible for glycemic control, like insulin and glucagon. With more insulin, glucose is transported inside the cells for energy expenditure. This subsequently aids in further weight loss.

热推

#bodybuilding #peptides #loss weight #health #benefits #Semaglutide #Tizepatide #liraglutide #retatrutide #injection #growth #energy #fat

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deer1006 · 10 months

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What kind of side effects do you encounter when you use Tirzepatide?

Tirzepatide may cause side effects. If any of these symptoms are severe or do not go away, you should consult your doctor:

vomiting, nausea, diarrhea, decreased appetite, constipation, upset stomach.

Some side effects can be serious. Call your doctor right away and stop taking this medication if you have any of the following symptoms or any of those mentioned in the Important Information section:

1、stomach pain that will not go away (and may radiate to the back) with or without vomiting.

2、Tizepatide may result in hypoglycemia, or low blood sugar.

Low blood sugar symptoms and warning indications might include headache, jitteriness, perspiration, slurred speech, dizziness or lightheadedness, anxiety irritability, or mood swings, hunger disorientation or sleepiness, shakiness, weakness, and headache.

Other adverse effects from this medication are possible. If you have any odd issues while using this drug, see a medical practitioner right away.

#Tirzepatide #weight loss #peptide #polypeptide #side effects #weight management #diet #peptides

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polypeptide555 · 10 months

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Semaglutide for weight loss - What you need to know

①.What is Semaglutide?

Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist that helps to regulate appetite and insulin. It works by stimulating GLP-1 receptors in the brain, which causes the body to feel full after eating smaller portions of food. It also helps reduce fat levels in the body by increasing insulin sensitivity, helping to control blood sugar levels. It is the first FDA-approved drug since 2014 for chronic weight management in overweight adults or adults with general obesity.

②.Here are five reasons to consider semaglutide for weight loss.

1.Semaglutide helps you lose weight gradually and safely.

Semaglutide works by reducing your hunger and cravings by lowering your appetite and slowing down digestion, making it easier for you to stick to a low-calorie diet. It also helps reduce the amount of fat stored in your body, leading to gradual and safe weight loss.

2. Semaglutide can help you keep the weight off.

Unlike other weight loss medications, which only work while they’re in your system, semaglutide has been shown to promote lasting weight loss by helping you stick to a healthy diet and lifestyle even after discontinuing the medication.

3.Semaglutide helps improve metabolic health.

In addition to helping you lose weight, semaglutide also reduces your risk of developing type 2 diabetes by improving your body’s ability to use insulin, as well as reducing inflammation and cholesterol levels.

4.Semaglutide is generally well-tolerated.

Most people who take semaglutide experience minimal side effects, such as nausea, headache, and constipation. The most common side effects are usually mild and can often be managed with lifestyle modifications or over-the-counter medications.

Please click to learn more.https://www.polypeptide.ltd/

#weight loss #semaglutide #peptides #health #drug blog #injection #benefits #type 2 diabetes #exercise #healthcare #insulin

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davidcuniverse · 10 months

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Dr Tony Huge...Dumb Ass

I can’t believe I am allowing myself to get triggered by the internet… but here we are. The fitness industry has become such a shit show. There are so many shitfluencers pushing lies and a lot of impressionable folks falling for these lies. The biggest lie of them all is the narrative that these fit people are natural.I have always loved fitness.. Specifically body building and it all started…

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#aneurysm #Arnold Schwarzenegger #blood clot #Dr huge #fitness #gear #hearns #heart attack #hrt #hulk #jab #Jo Dinner #joesthetics #Lou Ferrigno #peptides #sarms #steroids #trt

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kbeautynotes · 10 months

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How to Remove Neck Lines: Effective Methods for a Youthful Neck

Aging and lifestyle changes are no strangers to our bodies, and it’s only natural that they bring about transformations.

But here’s the kicker: some of our habits can actually make matters worse for our skin. In this guide, we will explore various techniques and strategies on how to remove neck lines and prevent them effectively.

Full blog post: How to Remove Neck Lines Effectively

What are your tips on maintaining the neck area?

#skincare #skincare tips #neck care #neck lines #neck wrinkles #youthfulskin #wrinkle prevention #fine lines and wrinkles #wrinkle treatment #wrinkle free #beauty tips #moisturising #peptides #red light therapy #radiofrequency #beauty blogger

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elevenelevenskin · 1 year

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A post shared by Eleven Eleven Skin LLC (@elevenelevenskin)

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We are excited to be featured in the VOGUE UK MAY 2023 issue of "Reframing Fashion" with the inspirational @selmablair on the cover, also "The Coronation Special! - The feature is at "The Fresh Faced Beauty" section with our AMAZING CALMING REDNESS REDUCTION SERUM, a power-house when it comes to deep hydration, full of collagen and antioxidants by natural pomegranate!... Great for sensitive skin.

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