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#cdc now says
mildmayfoxe · 3 months
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sealed my bedroom door extremely haphazardly but to the best of my current ability with several different foam weather stripping tapes & a draft snake & a towel & armed with my new bigger air purifier that is way overpowered for my room that will change out the air in here approx every six minutes i am about to sleep without a mask on for the first time since JANUARY SECOND
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one-true-houselight · 2 years
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What is the point of requiring masks to walk into a building, only to leave it up for personal choice once people sit down for a performance? Do you understand how masks work?
#look. obviously the most relevant reason to be distressed about waning COVID precautions is the death and eugenics#but the personal things are hitting hard as well#there’s a show coming to DC that me my sibling and my mom all really want to go to#but a. saw people saying that was how enforcement was working which renders it unsafe#as well as b. the venue does food/drink anyway which annoys me in its own way#remember when we were all making fun of some conservative asshole for acting like taking off your mask ‘just to eat’ was good enough?#bc we realized viruses don’t care why we’re taking off our mask#but now suddenly it’s al masks are required unless eating or drinking#basically cancelling a large portion of any protection you might have gained.#and for what? so people could eat some popcorn or have a beer inside#(obviously it’s different for people with blood sugar/etc medical needs#but it’s not like anyone cares about disabled people any other time vis a vis masks so I don’t fully believe they actually care about#finding an equitable solution ya know?)#fuck the government and cdc for sacrificing people on the altar of capitalism#but also fuck people who can’t wear a mask/quarantine/not go out/etc to keep disabled people alive and even slightly welcome in public#yeah my mental health would be better if I went out more!#except! it would be balanced out by the negative impact of all the people I’m condemning to isolation and death#we have solutions we know solutions#but people were left to the mercies of a government that didn’t care and were bombarded by individualistic bullies in its place#so now a show that is literally synthesized to be my jam#is a biohazard.
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elastica1995 · 2 years
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pulled a tick off my scalp i’m gonna kill myself
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awkward-teabag · 2 years
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Forgot to post it here but behold BC's greatest minds advocating for infecting/killing infants.
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I have nothing but bad news for y'all
We were supposed to have until April to leave comments, but the cdc has officially ended the 5 day isolation period as of today, March 1st, 2024.
They're saying as long as it's been 24hrs and your symptoms are improving, you're good.
Nothing about covid has changed. Medical professionals are obviously slamming this decision. All this does is make it even more difficult to avoid long covid, because now workers will have to fight for sick days and time off they already barely have just to fucking heal from an organ damaging virus.
Idk what to say for this one.
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thistlecrimes · 4 months
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Things I've learned from getting covid for the first time in 2023
I wear an N95 in public spaces and I've managed to dodge it for a long time, but I finally got covid for the first time (to my knowledge) in mid-late November 2023. It was a weird experience especially because I feel like it used to be something everyone was talking about and sharing info on, so getting it for the first time now (when people generally seem averse to talking about covid) I found I needed to seek out a lot of info because I wasn't sure what to do. I put so much effort into prevention, I knew less about what to do when you have it. I'm experiencing a rebound right now so I'm currently isolating. So, I'm making a post in the hopes that if you get covid (it's pretty goddamn hard to avoid right now) this info will be helpful for you. It's a couple things I already knew and several things I learned. One part of it is based on my experience in Minnesota but some other states may have similar programs.
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The World Health Organization states you should isolate for 10 days from first having symptoms plus 3 days after the end of symptoms.
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At the time of my writing this post, in Minnesota, we have a test to treat program where you can call, report the result of your rapid test (no photo necessary) and be prescribed paxlovid over the phone to pick up from your pharmacy or have delivered to you. It is free and you do not need to have insurance. I found it by googling "Minnesota Test to Treat Covid"
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Paxlovid decreases the risk of hospitalization and death, but it's also been shown to decrease the risk of Long Covid. Long Covid can occur even from mild or asymptomatic infections.
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Covid rebound commonly occurs 2-8 days after apparent recovery. While many people associate Paxlovid with covid rebound, researchers say there is no strong evidence that Paxlovid causes covid rebound, and rebounds occur in infections that were not treated with Paxlovid as well. I knew rebounds could happen but did not know it could take 8 days. I had mine on day 7 and was completely surprised by it.
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If you start experiencing new symptoms or test positive again, the CDC states that you should start your isolation period again at day zero. Covid rebound is still contagious. Personally I'd suggest wearing a high quality respirator around folks for an additional 8-9 days after you start to test negative in case of a rebound.
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Positive results on a rapid test can be very faint, but even a very faint line is positive result. Make sure to look at your rapid test result under strong lighting. Also, false negatives are not uncommon. If you have symptoms but test negative taking multiple tests and trying different brands if you have them are not bad ideas. My ihealth tests picked up my covid, my binax now tests did not.
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EDIT: I'd highly suggest spending time with friends online if you can, I previously had a link to the NAMI warmline directory in this post but I've since been informed that NAMI is very much funded by pharmaceutical companies and lobbies for policies that take autonomy away from disabled folks, so I've taken that off of here! Sorry, I had no idea, the People's CDC listed them as a resource so I just assumed they were legit! Feel free to reply/reblog this with other warmlines/support resources if you know of them! And please reblog this version!
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I know that there is so much we can't control as individuals right now, and that's frightening. All we can do is try our best to reduce harm and to care for each other. I hope this info will be able to help folks.
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fiercynn · 2 months
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okay, if you have ever made or reblogged a “hold your nose and vote for biden” post, this is for you.
here’s the fucking thing about these kinds of posts. i've been seeing them since i first returned to tumblr in, I think, late 2022? they've certainly increased in frequency since october 7, but they were there before too, ready to counter any kind of opposition to biden that has cropped up. many of them are not just trying to educate people about what positive things biden has done, which, like, at least I can understand the motivation behind those ones? but so many of them are directly in response to people criticizing biden, and their only real point is “sure you’re upset at this thing biden did, but have you considered the election?” starting YEARS before the next presidential election, mind you.
and october 7 only made that clearer. i don’t think it had been a week before i saw these posts cropping up. can you not see how fucking ghoulish that is? to look at the rightful pain and anger of those whose relatives and communities are being slaughtered with active american support, to respond to one of the few pieces of agency most americans have in influencing what their governments do – their vote – by saying “yes but trump would be worse.” as if the primary people you’re lecturing – palestinians, muslims, arabs, black people, indigenous people, disabled people, other marginalized people – don’t remember exactly how bad it was under trump!
and even if you think not voting is an empty gesture – something i, who studied political science at a mainstream american lib college, who has worked as a field organizer on a previous democratic presidential campaign and for several policy campaigns, who currently works in public policy in america, used to believe, but have absolutely changed my mind on – what is in no way an empty gesture is saying publicly that you will not vote for someone. the arguments people usually have about why simply not voting is bad are that you can’t tell why someone is not voting, so it is as likely to be apathy or disenfranchisement as it is a political statement. but saying publicly that you will not vote for someone, and why you will not vote for them, absolutely is a political statement, and potentially a powerful one! but you choose to negate and/or ignore that by trotting out the “lesser of two evils” bullshit.
and then there’s the whole “yes but people will DIE under trump”. PEOPLE ARE DYING NOW. even if you’re fucking racist and have decided that palestinian lives don’t count, have you forgotten biden’s ongoing covid minimalism and dismantling of the CDC’s covid research and prevention infrastructure? have you forgotten his increase in spending for law enforcement scant years after the murder of george floyd and his administration's surveillance of protesters, including cop city protesters? have you forgotten his recent ramp-up in deportations of undocumented immigrants, including the active continuation of many trump-era policies?
maybe you have forgotten all those things and do purport to care about palestinians, but you just think that biden is doing his best to influence netanyahu and is getting nowhere! but then you must have forgotten all of the things that biden and his administration themselves have done to further this fucking genocide, including:
continuing to send arms to israel
putting together a military task force within days of yemen’s red sea blockade and attacking yemeni ships
bombing yemen
bombing syria
bombing iraq
vetoing three ceasefire resolutions at the united nations
testifying to defend israel and its genocide and occupation at the international court of justice
refusing to rescue palestinian-americans stuck in gaza
halting funding to the united nations relief and works agency for palestinian refugees (UNRWA) based on israeli claims that 12 of UNRWA’s over 30,000 staff were hamas agents, even though u.s. intelligence has not been able to independently verify this
lying that he’s personally seen photos of babies beheaded by hamas when he hadn’t because they didn’t exist (and even when his own staff cautioned him that reports of beheaded babies may not be credible)
questioning the number of palestinian deaths reported by the gaza ministry of health (when even israel has not questioned them, since they are in fact proud of those numbers)
perpetuating lies about hamas having committed the attack on al-aqsa hospital
questioning united nations reports of adults and children raped by israeli soldiers while claiming to have proof (that no one else has seen) of hamas doing the same
honestly so many more things that i can’t remember them all but others feel free to add
or maybe you haven’t forgotten any of that, and think that you’re still justified in lecturing people about why they should vote for biden, because you genuinely believe trump would still be worse. if that is the case, you have still failed to see that by saying you will vote for biden no matter what, you are part of the problem of biden continuing to act like this. because biden is counting on fear of trump to win him this next election no matter what else he does. despite his appalling polling numbers, despite the knowledge that he is losing the palestinian-american vote, the arab-american vote, the muslim-american vote, the black american vote, the youth vote – despite all of that, he is secure in the idea that he will still win because he is better than trump. can you not see how that allows him to act without impunity? how it becomes increasingly impossible for his base to influence what he’s doing if he thinks that they will be with him no matter what? this is how you make yourself complicit to biden’s actions, by not affording anyone even the slightest power to hold him accountable for anything.
and in most cases, the “hold your nose and vote for biden” thing is the response of people who aren’t even being instructed by others not to vote for biden. it is their response to people saying they themselves are choosing not to vote for biden. fucking ghoulish.
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reasoningdaily · 10 months
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My former U.S. Track and Field teammate Tori Bowie, who was found dead in her home in Florida on May 2, of complications related to childbirth at 8 months pregnant, was a beautiful runner. She was effortless. At the Rio Olympics, I ran the second leg of the 4 x 100 relay. Tori was the anchor. When she got the baton, I remember thinking, “it’s over.” She just accelerated. When she crossed the finish line, I couldn’t wait to run over to her to celebrate. It was her first, and only, Olympic gold medal.
She also picked up a silver (in the 100-m) and bronze (200-m) in Brazil. The next year, at the 2017 World Championships in London, Tori won the 100-m title, earning the title of “world’s fastest woman.” Tori started out as a long jumper. So seeing her thrive as a sprinter was a huge deal. She was just such a bright light, and people were getting to see that.
Tori grew up in Mississippi and had this huge Southern accent. She didn’t take herself too seriously. You felt this sense of ease when you were around her. I last saw her in early 2021, in San Diego, where she was training. She gave me the biggest hug; something about her spirit was just very, very sweet. I felt her sweetness come over me that day.
Tori was 32 when she died. According to the autopsy, possible complications contributing to Bowie’s death included respiratory distress and eclampsia—seizures brought on by preeclampsia, a high blood pressure disorder that can occur during pregnancy. I developed preeclampsia during my pregnancy with my daughter Camryn, who was born in November 2018. The doctors sent me to the hospital, where I would deliver Camryn during an emergency C-section, at 32 weeks. I was unsure if I was going to make it. If I was ever going to hold my precious daughter.
Like so many Black women, I was unaware of the risks I faced while pregnant. According to the CDC, in 2021 the maternal mortality rate for Black women was 2.6 times the rate for white women. About five days before I gave birth to Camryn, I was having Thanksgiving dinner with my family. I mentioned that my feet were swollen. As we went around the table, the women shared their experiences during pregnancy. My cousin said she also had swollen feet. My mom didn’t. Not once did someone say, ‘oh, well, that’s one of the indicators of preeclampsia.’ None of us knew. When I became pregnant, my doctor didn’t sit me down and tell me, ‘these are things that you should look for in your pregnancy, because you are at a greater risk to experience these complications.’
That needs to change, now, especially in light of Tori’s tragic passing. Awareness is huge. Serena Williams had near-death complications during her pregnancy. Beyoncé developed preeclampsia. I hate that it takes Tori’s situation to put this back on the map and to get people to pay attention to it. But oftentimes, we need that wake-up call.
The medical community must do its part. There are so many stories of women dying who haven’t been heard. Doctors really need to hear the pain of Black women.
Luckily, there’s hope on several fronts. Congress has introduced the Momnibus Act, a package of 13 bills crafted to eliminate racial disparities in maternal health and improve outcomes across the board. California passed Momnibus legislation back in 2021. These laws make critical investments in areas like housing, nutrition, and transportation for underserved communities. Further, several pharmaceutical companies are making advances on early detection and treatment of preeclampsia.
Three gold medalists from that 4 x 100 relay team in Rio set out to become mothers. All three of us—all Black women—had serious complications. Tianna Madison has shared that she went into labor at 26 weeks and entered the hospital “with my medical advance directive AND my will.” Tori passed away. We’re dealing with a Black Maternal Health crisis. Here you have three Olympic champions, and we’re still at risk.
I would love to have another child. That’s something that I know for sure. But will I be here to raise that child? That’s a very real concern. And that’s a terrifying thing. This is America, in 2023, and Black women are dying while giving birth. It’s absurd.
I’m hopeful that things can get better. I’m hopeful that Tori, who stood on the podium at Rio, gold around her neck and sweetness in her soul, won’t die in vain.
—as told to Sean Gregory
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fairuzfan · 24 days
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Would you rather have a president that enables a genocide? Or would you rather have a president that vilifies immigrants, promotes facism, dismantles the rights of women and minorities, emboldens white nationalists, worsens the wage gap, defunds vital services, AND enables a genocide?
It's an unfair and unreasonable question to ask. I know. Unfortunately those are our choices for president. It sucks, but it's a 2 party system. And until any change is made where a 3rd party vote is no longer equivalent to not voting at all, it's better to just vote blue for the presidential election. Not because Democrats are the "lesser evil", but because NOT having a Republican president will prevent further suffering of Americans and will lessen the risks of minorities' rights being threatened and revoked.
The president chooses the members of the supreme court who hold lifelong positions and whose legal decisions have decades-long ramifications. Trump picked 3 of the 11 current members who currently hold a Republican majority. It was that supreme court that overturned Roe V Wade and that decision is harming thousands of people today in multiple states.
Biden already nominated one SCOTUS, and in his next term he could appoint 1-2 more Democratic members who would work to protect rather than erode American rights.
The Trump administration was lethal for thousands of Americans for a multitude of reasons, including his failure to properly respond to and then proceeded to politicize the COVID-19 pandemic.
As awful as it sounds, as hard as it is to believe in the moment, ESPECIALLY with the atrocities Biden is perpetuating in Palestine right now, don't believe for a moment that this genocide would be even slightly less cruel under Trump. The difference is Trump's cruelties would extend to Americans as well— especially immigrants.
The point I'm making is the only ethical choice for this election is to vote for Biden, but at the same time that vote is not the same as condoning his actions. Don't let voting be the end all for political action, and I hope you understand why this choice is necessary in an unfair voting system. Please participate in your local elections, Call your representatives. Continue demanding a permanent ceasefire and an end of Israel's occupation over Palestine. And please keep helping Palestinians.
I think it's quite wild to say people domestically haven't been dying under Biden. Hundreds of thousands disabled people have died during the Biden presidency due to covid. I myself only got covid because people around my family stopped masking. Even some of my family members stopped masking because of the CDC thing. There have been countless other things that I'm too tired to list as well that directly contributed to the death of people.
I'm sorry I don't know why you sent this I'm not going to change my mind. I'm not voting for the man that killed people I know and lied to our faces about it.
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reiderwriter · 2 months
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Okay but, flirty reader majority pointed at Reid, and the scene where he has to get hosed down and says "I'mma bout to get naked, I don't think you wanna see that" and reader's just like raising her hand and says "don't worry I'll stay". And after she walks out to go to the hospital and sees everyone and with an open mouth and wide eyes just goes " woah" cause big dick energy
A/N: Hi, thank you so much for your request! I've been a bit sick lately, so I haven't had a chance to write much, but this was fun and quick to write! I might do a part 2 with the actual smut in the future, so if that's something people would want let me know in the comments!!
Warnings: suggestive content, public dirty talk?
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“I really want to see that.” 
You heard the words but weren't sure where they'd come from for the longest time. It had been a confusing morning, with a high alert for anthrax and your coworker trapping himself inside a contaminated lab to save you from dying a presumably very painful death, you couldn't be blamed for not realizing that you'd said the words in question. 
He'd meant the words sarcastically, of course, and they'd warned Morgan off immediately with a chuckle and a “You better survive this, kid,” but you'd stood rooted to the earth until he'd repeated them again. 
“Y/N, they're going to strip me down. You don't want to see that.” 
“I really do, though.” Your eyes unabashedly trailed down the contours of his body, soaked from the hoses currently decontaminating him. You could've sworn that he was moving in slow motion as his hand pushed back his hair and cleared his face of water. 
If there weren't this many CDC agents around, you'd have likely joined him in his impromptu shower to feel your way along the lines of his clothing, checking to see what was outline and what was the thick layers of shirt and pants that unfortunately still obstructed your view. 
Another minute of you ogling him went by before your eyes finally returned to anywhere near his, and you realized that your desire for the man could no longer pass for camaraderie. 
“You better not die, Spencer. Not before I can enjoy the meal I'm about to sample.” 
His doctors were either ignoring the conversation completely or were busy focusing on other things, and luckily, they didn't react to your words. Other than to take Spencer's temperature one more time when he flushed bright red, and stared at you slack-jawed. 
“We're going to have to speed this along, Doctor Reid. Please start unbuttoning your shirt,” one of the hazmatted men said to him, but his eyes were fixed on you. 
“Yes, please do, Spencer. It's for your own good. And mine.” 
You expected him to blush and fawn again, but his day had been as long and confusing as your own, so you were unsurprised when he looked you directly in the eye and began unbuttoning his shirt. You watched his descent, and your breath faltered, seeing the water drip down his bare skin now. 
“I'm not sure which of us is wetter right now,” you tried to joke in earnest, but you felt a sharp jolt of lust in your gut as soon as his hands reached his belt. 
“Y/N, you need to leave now. Before you make this any harder for everyone here.” The innuendo in his words were clear, but you were thankful again for the considerate and/or oblivious doctors either side of him bagging up his discarded shirt and jacket. 
“Only if you promise I can make your life as hard as I want to when you're in the clear.” You smiled again, hoping the full force of your lust would reach him. Spencer was always oblivious to genuine flirtation, you'd observed enough women throwing themselves on him (had discouraged a few too many with a hand on his arm and a finger playing with the abandoned curls at the back of his neck, too) to know that for sure. 
You needed to make your need for him explicit. 
“I mean it, Spencer. I really mean it.” 
His eyes locked with yours for the last time ad you made to turn around, doing your best to convince him without becoming distractedly horny. 
“I know. I'll see you at the hospital.” 
“At the hospital? Risky, I like it.” You winked and turned away, leaving him calling back after you as you walked over to the car Derek had pulled around the front of the property. 
“Wait, not the hospital! Those beds aren’t comfortable. Y/N! Y/N, really!” 
You giggled as you sat down in the car, but you bubbled with anticipation still. 
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fortunesrevolver · 1 year
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Hello everyone! I am a doodler and maker of things sometimes. Most of the items I currently sell are vinyl decals and resin coasters, but I wanted to make a post exclusively showing off the more traditional stickers I've made, as I don't think they get very much attention at all and they're probably a few of the items I'm most proud of.
I'm still newer to the small business and Etsy game, but I hope seeing these help brighten someone's day -- or maybe you just know someone who loves slapping stickers on stuff. (Like me. I love stickers.)
Also! Currently all resin coasters in my shop are on sale until November 24th, 2022!
✯ My Shop ✯ My KoFi ✯ Twitter ✯ Instagram ✯
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feminist-space · 5 months
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"Seminario cited the recent report, “Employer-Reported Workplace Injuries and Illnesses,” that shows that the number of respiratory illnesses in the private health care and social assistance sector increased from 145,300 in 2021 to 199,700 cases in 2022, an increase of 37.5 percent.
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As an industrial hygienist, Seminario was extremely critical that there were no experts in respiratory protection on the committee nor did it include engineers who developed ventilation guidelines. She believes that the HICPAC committee members are likely so opposed to respirators “because once you are into recommending respiratory protection, with that comes a full respiratory protection program from OSHA,” with penalties for violations.
An epidemiologist and consultant, Michael Olesen, echoed this, believing the changes reflect “pressure to remove liability from hospitals.” He added, “I take a very clear position that we should be having respiratory protection mandates in all healthcare settings right now.”
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Many patients who spoke at the HICPAC meetings said they had gotten Covid-19 when they went to the hospital and that the new policies were keeping them from getting care.
Given that, Dr. Art Caplan, professor of medical ethics at New York University’s Grossman School of Medicine, previously told me that dropping masking requirements in hospitals is “utterly, completely, irresponsible.” Similarly, staff refusing to mask, even when a patient requests it, is a moral failure. “The first principle is, you must do what is in the best interest of your patient,” he said.
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Several people were asked why they believe HICPAC is determined to water down protections. Consistently, respondents say, “to reduce liability.” Earlier in the pandemic, hospitals regularly tested patients and staff for Covid-19, and you could often tell where and how you became infected. Since staff are no longer masking and continue working when ill, and patients are not being tested on admission, you can no longer prove who infected you. Hospitals are the only ones who win in this scenario, absolving themselves of responsibility and liability."
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optimist-pine · 2 months
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Returns
Pairing: Daryl Dixon x Reader
Warnings: None
Summary: Daryl finds something in his pack that doesn't belong to him... (ps. it's yours)
Era: Season 2, the farm
A/n: This is a silly little thank you for everyone who's been supporting my writing! If you've liked/commented/reblogged any of my works recently, this is for you. :)
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Daryl digs around in his backpack, shoving aside arrow bits and extra clothes in the search for a clean(ish) rag he knows is buried in here somewhere. Ah, there, the glimpse of a red hue must be what he's looking for. He tugs it free, but as he brings it into the daylight it comes to his attention that this piece of cloth doesn't belong to him.
He drops it immediately, head swiveling to make sure nobody saw. But no, he's tucked far away from the rest of the group, not a soul in sight. He gingerly picks up the garment before realizing how ridiculous he's being and shoves it in his pocket. He'll slip into your tent, return it, and get the hell out of there and get on with the rest of his day.
Everyone's either dispersed to other parts of the farm or busy enough completing whatever chores they've taken on to notice him. Even if he didn't already know which tent was yours, it'd be obvious from the plethora of herbs and flowers hanging to dry by the entrance, and the dog-eared foraging guidebook waiting on a lawn chair for your return.
He peers through the screen window to assure himself that you're not around before unzipping the door and stepping inside. A moment too late, he realizes the amount of dirt he's just tracked into your otherwise pristine living space, and curses. Nothing to do about it now he supposes. He squats down, opening your pack and pulling the wayward item out of his pocket.
"Daryl? What're you doing in my-" Your voice makes him jump before your words falter.
His head snaps to you; you're bent down a bit, hands on your hips with sweat dripping down your temple. Your mouth is stuck in a cute little "o" of pure confusion. He's frozen, hand halfway between him and your belongings, lungs stuck mid-breath. He really should say something in his own defense.
"Is that my underwear?" You ask a little more quietly.
"I - uh..." He gapes. He's invading your privacy in so many ways, you're going to think he's a total ass if not a complete creep. And he actually doesn't mind you too much so he doesn't want you to think of him in that way. Not that you think of him at all. But now when you do you're going to hate his guts. "They - uh..." He tries.
"Ohh. I get it." You say, nodding, like this all makes total sense. "I've got something of yours I've been meaning to return, just wasn't sure how to make it not-awkward..." You kneel down beside him, fishing around in a side compartment on your bag. "Buuuut no matter. I believe these belong to you." You hold out a pair of faded boxers that've been rolled up neatly.
"Hey, Rick wants to know if-" Glenn appears in the tent opening and Daryl can practically see the gears struggling to turn in his head as he takes in the two of you so close together, each obviously holding the other's intimates. "Y'know what? Nevermind. Just go talk to Rick when you're done or whatever, okay?" He sighs, walking away.
Daryl wastes no time grabbing his boxers, shoving them in his pocket. You do the same but with more grace, standing to brush off your pants.
You let out a small chuckle, biting down a bit on your lip. "It was so hectic when we left the CDC; must've grabbed each other's stuff then." You step outside and he follows. "Thanks for returning them." You say, stooping to re-zip the tent.
The CDC is such a blur that it takes effort to remember. There weren't enough rooms for everyone and so you'd asked to bunk with him. Even though he was sufficiently intoxicated that night, he'd been lucid enough to appreciate not being alone, your steady breaths in the unsettling darkness had quieted his nerves.
He can't seem to make his eyes stay on you for long, though that doesn't stop your gaze from lingering - he can practically feel every place your eyes land as you study him. "S'no problem." He shrugs.
"Well, I guess I'd better go see what Rick wants..." you sigh, making no noticeable effort to go anywhere.
You're leaving a space for him to say something but he doesn't really have anything to add to that. "Yeah." He replies dumbly.
A soft smile grows upon your lips. "Don't be a stranger, okay? Some of us actually enjoy your company." You nudge his shoulder good-naturedly as you walk away.
He mulls over your words, trying dissect what that last little bit means. You were just being kind, right? He's pretty sure people have barely put up with his company, let alone enjoyed it. Realizing you've already been gone for multiple minutes he pushes those thoughts to the back of his mind and trudges off, noting that there's at least a few hours of good daylight left to make use of. But those thoughts are still there, nagging, toying with him.
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A couple of days later, when Daryl returns to his camp after a successful enough trip into the woods, there sits your well-loved guidebook. It's laying on the ground where you must've set it when you stopped by earlier and forgotten it when the two of you headed out. He picks it up, flipping through the bent pages and your frequent notes when he passes one that makes him stop and turn back. Next to chanterelle mushrooms you've scribbled 'Daryl - pair w/ venison' . He hadn't caught game that big since back at the quarry, and even then the geeks got to it first. A small swell of pride rises within him at the thought of you planning ahead in this way, of you counting on him to provide.
The feeling follows him as he settles down for the night. Pulling out a flashlight he figures he might as well see if there's anything he can learn from your book... Or maybe that's just an excuse to search for more of your annotations. He'll have another return to make in the morning, but he can't quite bring himself to mind all that much.
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mariacallous · 7 months
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Updated vaccines against Covid-19 are coming, just as hospitalizations and deaths due to the virus are steadily ticking up again.
Today, the US Food and Drug Administration authorized new mRNA booster shots from Moderna and Pfizer, and a panel of outside experts that advises the Centers for Disease Control and Prevention voted to recommend the shots to everyone in the United States ages 6 months and older. Once Centers for Disease Control and Prevention director Mandy Cohen signs off on the recommendations and the vaccines are shipped, people can start getting the boosters.
The recommendation is projected to prevent about 400,000 hospitalizations and 40,000 deaths over the next two years, according to data presented at the meeting by CDC epidemiologist Megan Wallace.
This year’s mRNA vaccines are different from the 2022 booster in a key way. Last year’s shot was a bivalent vaccine, meaning it covered two variants: the original one that emerged in China in 2019, plus the Omicron subvariant BA.5, which was circulating during much of 2022. This fall’s booster drops the original variant, which is no longer circulating and is unlikely to return. It targets just the Omicron subvariant XBB.1.5, which was dominant throughout much of 2023.
Pfizer and Moderna’s vaccines work by introducing a tiny piece of genetic material called messenger RNA, or mRNA, that carries instructions for making SARS-CoV-2’s characteristic spike protein. Once it is injected, cells in the body use those instructions to temporarily make the spike protein. The immune system recognizes the protein as foreign and generates antibodies against it. Those antibodies stick around so that if they encounter that foreign invader again, they will mount a response against it.
Since the start of the Covid-19 pandemic, the virus has acquired new mutations in its spike protein and elsewhere. These mutations result in new variants and subvariants that diverge from the original virus. When enough mutations accumulate, these new versions can more easily evade the antibodies created by previous vaccine doses or infections.
The constantly evolving nature of the virus is the reason health regulators decided last year to update the original mRNA vaccines, which were designed against the version of the virus that first appeared in 2019. This year, once again, the virus has changed enough to warrant an updated booster.
In June, an advisory committee to the FDA recommended that this fall’s booster be a monovalent vaccine—targeting only the then-dominant XBB.1.5 subvariant.
At that meeting, committee members reviewed evidence suggesting that the inclusion of the original variant may hamper the booster’s effectiveness against newer offshoots. “The previous bivalent vaccine contained the ancestral spike and thus skewed immune responses to the old spike,” says David Ho, a professor of microbiology at Columbia University whose research, which is not yet peer-reviewed, was among the evidence the FDA panel reviewed. “This is what we call immunological imprinting, and it results in lack of immune responses to the new spike.” He thinks taking out the old variant should optimize the immune response.
But over the past few months, even newer Omicron offshoots have arrived. Currently, EG.5.1, or Eris, is the dominant one in the United States, United Kingdom, and China. Meanwhile, a variant called BA.2.86, or Pirola, has been detected in several countries. Pirola has raised alarm bells because it has more than 30 new mutations compared to XBB.1.5.
Even though the new boosters were formulated against XBB.1.5, they’re still expected to provide protection against these new variants. “The reason is, while antibodies are important in protection against mild disease, the critical part of the immune response that’s important for protecting against severe disease is T cells,” says Paul Offit, a professor of vaccinology at the University of Pennsylvania and member of the FDA’s vaccine advisory committee.
These cells are a different part of the immune response. Unlike antibodies, which neutralize a pathogen by preventing it from infecting cells, T cells work by eliminating the cells that have already been invaded and boosting creation of more antibodies. Both the Moderna and Pfizer-BioNTech Covid vaccines produce long-lasting T cells in addition to antibodies.
It’s why, Offit says, when the Omicron wave hit in late 2021 and peaked in January 2022, the US didn’t see a dramatic increase in hospitalizations and deaths even as cases rose significantly: People’s T cells kicked into gear, even when their antibodies didn’t recognize the Omicron variant.
“In some ways,” says Offit, when it comes to vaccine booster development, “it almost doesn’t matter what we pick to target” because the coronavirus has yet to evolve away from T cell recognition. “Everything works.”
Scientists think T cells are able to protect against severe Covid because they’re recognizing parts of the virus that have remained unchanged throughout the pandemic. “I suspect that as we continue to vaccinate, there are some conserved regions [of the virus],” says Jacqueline Miller, Moderna’s head of infectious diseases. “So even with the accumulation of mutations, we’re still building on previous immunity.”
People who have hybrid immunity—that is, have had a Covid infection and have also been vaccinated—seem to have the best immune responses to new variants, she says, which suggests that previous exposure shapes and improves immune responses to new variants. Preliminary studies show that antibodies generated by previous infections and vaccinations should be capable of neutralizing Pirola.
Earlier this month, Moderna issued a press release saying that clinical trial data showed that its updated booster generated a strong immune response against Pirola, as well as the more prevalent Eris variant.
In a statement to WIRED, Pfizer spokesperson Jerica Pitts said the company continues to closely monitor emerging variants and conduct tests of its updated monovalent booster against them. Data presented at Tuesday’s CDC meeting showed that Pfizer-BioNTech’s updated booster elicited a strong neutralizing antibody response against both Eris and Pirola.
The FDA expects that Covid-19 vaccines will continue to be updated on an annual basis, unless a completely new variant emerges that requires a different approach. “We will always be a little behind the virus,” says Ho. “In this instance, we won’t suffer too much, but that might not be the case going forward. Surveillance is imperative.”
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nominalnebula · 2 years
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so my coworker’s (who I share an office with) 13 yr old son came down with covid last week. she’s hoping she has enough immunity from when she had it early this year that she’ll be fine. and no, no one in her family is vaccinated.
happy monday, I would like to be removed from this narrative please.
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