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grimestimes · 4 years

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Return the shopping cart?

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grimestimes · 4 years

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grimestimes · 4 years

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“no more after me”, a mini comic about the now-extinct golden toad. featuring lyrics from deuteronomy 2:10 by the mountain goats

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grimestimes · 4 years

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grimestimes · 4 years

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Have you ever come across Blue Carpenter Bees (Xylocopa caerulea)? I’ve just seen a post about them on Facebook and they’re so adorable and such a pretty colour!!

I’ve never seen one in person since they’re not native to where I live. But here’s one for everyone to admire:

This one was photographed in Malaysia by gancw1 on iNaturalist. That is a nice bee.

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grimestimes · 4 years

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The terms “pseudo-merle" or “merle effect” are only used here because there is no current term for this phenomenon in cats. I’ve used the terms descriptively, not genetically. I’ve used these terms to refer to non-dilute patches on a dilute colour, or to non-silver patches on a smoke, tipped/chinchilla or shaded silver cat.

In cats, there is no clearly identified gene and the effect it appears to be cosmetic only. Observation finds it to occur in smoke, tipped and shaded silver cats where some patches lack the silver undercoat. It appears to be most common on red-silver (chinchilla or shaded silver) cats that have non-silvered patches. It can occur in any breed…

A pseudo-merle is found in the Topaz breed bred by Iryna Merzlenko (Cattery Nikita'l, Ukraine). These blue/black merle-pattern cats all have the silver gene and cannot all be chimeras due to their frequency. Although they look like a mix of smoke and solid colour, the different colours are due to the silver (inhibitor) gene working unequally in different parts of the coat giving darker and paler areas, but all with silver close to the skin. It appears to be linked to the blue-eye mutation and has occurred in a number of cats (and these are genetically related to the famous blue-eyed "Narnia” with his blue-and-black face, albeit not having the silver gene). Merle colour has been found in every litter with smoke kittens, and is often located on the belly or legs.

The underlying genetics are not yet known. No single mutation has been identified so genetic explanations are based on observation and on “what hasn’t been found.”

Many silvers seem to have some unsilvered patches, or patches where there is only a small amount of silver at the base of the hair-shaft. On those cats the expression of silver is variable, with a patchwork of light smoke and dark smoke areas. This could be due to polygene influences or even an unstable mutation that reverts during cell division i.e. a somatic mutation. For example, in e/e yellow/white dogs, these should have no black at all but often have scattered black hairs or small black patches.

Could white spotting increase the likelihood of merle effect, for example could it cause the coloured patches to clump and scatter as it does in calico cats? Or is it an optical illusion because the silver undercoat and white patches are hard for the human eye to easily distinguish? In tortie smokes, the red seems to be more affected that the black by the merle effect and this suggests that phaeomelanin deposition is more affected than eumelanin deposition (in the same way that the non-agouti gene does not completely eradicate striping in “self red” cats). Where some red appears lighter and some is darker, perhaps the theorised “chaos” and “confusion” polygenes are involved and disharmonize uniformity of hair ticking and clarity of tabby markings.

Leslie Lyons has theorized that “silver” (white undercoat) may not be an exome mutation and that the visual effect is due to clonal differences in the regulation of pigment production or pigment transport. Others suggest that silver is a bit unstable and tends to revert to wild-type. Clonal differences means a change occurs in a skin cell and when this cell divides and multiplies as the embryo or kitten grows, the daughter cells all inherit the change (the change might be subtle or might be dramatic). A single skin cell that somehow suppresses the silver gene could give rise to a distinct patch on non-silver fur. A single patch may break up and move apart as the skin surface increases, resulting in several coloured patches with the gaps filled in by the base colour.

If silver was an exome mutation, it would already have been found as the feline genome is well studied. The exome is the part of the genome formed by exons. Exons are DNA sequences which, when transcribed, remain within the mature RNA in cells of any type and not just transcribed in specific cells as part of cell specialization. Exomes account for a very small percentage of the genome, but exome mutations can have dramatic effects.

The red-silver dapple pattern also seems more common in combination with white spotting, which suggests a link. Unlike true merle [in dogs], this pattern in cats is not linked to recessive white. Because pedigree cats with this pattern don’t meet exhibition standards, there hasn’t been selective breeding for the trait so data is limited.

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grimestimes · 4 years

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